{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pain+Processing+Education",
    "query": {
      "intervention": "Pain Processing Education"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 14,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pain+Processing+Education&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-05T20:14:03.140Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02695498",
      "title": "Mindfulness and Mechanisms of Pain Processing in Adults With Migraines",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Migraine"
      ],
      "interventions": [
        {
          "name": "Mindfulness Based Stress Reduction",
          "type": "OTHER"
        },
        {
          "name": "Migraine/stress Education",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 89,
      "start_date": "2016-08-26",
      "completion_date": "2019-07-17",
      "has_results": true,
      "last_update_posted_date": "2023-11-27",
      "last_synced_at": "2026-09-05T20:14:03.140Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02695498"
    },
    {
      "nct_id": "NCT07071350",
      "title": "Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Autonomic Nervous System Disease",
        "Concussive Injury",
        "Mild Traumatic Brain Injury",
        "Post Traumatic Stress Disorder",
        "Persistent Post Concussion Syndrome"
      ],
      "interventions": [
        {
          "name": "HRV Coherence Ratio",
          "type": "OTHER"
        },
        {
          "name": "NSI",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pittsburgh Sleep Quality Index (PSQI)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Quantitative Sleep Measures",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Global Impression of Change (PGIC)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitive Performance/NIH Toolbox Cognitive Battery",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pain Interference/TBI-QoL Pain Interference Short-Form",
          "type": "OTHER"
        },
        {
          "name": "Patient Health Questionnaire-9 (PHQ-9)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "PTSD Checklist for DSM-5 (PCL-5)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "HRV Biofeedback (HRV-B)",
          "type": "OTHER"
        },
        {
          "name": "Psychoeducational (Edu) Comparator Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 148,
      "start_date": "2025-09-02",
      "completion_date": "2028-09",
      "has_results": false,
      "last_update_posted_date": "2025-09-17",
      "last_synced_at": "2026-09-05T20:14:03.140Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07071350"
    },
    {
      "nct_id": "NCT01794988",
      "title": "Can Therapy Alter CNS Processing of Chronic Pain: A Longitudinal Study",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Pain"
      ],
      "interventions": [
        {
          "name": "Group Cognitive Behavioral Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pain Education",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Therapeutic Interactive Voice Response",
          "type": "BEHAVIORAL"
        },
        {
          "name": "NO TIVR",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Vermont",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 120,
      "start_date": "2010-07",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2013-02-20",
      "last_synced_at": "2026-09-05T20:14:03.140Z",
      "location_count": 1,
      "location_summary": "Burlington, Vermont",
      "locations": [
        {
          "city": "Burlington",
          "state": "Vermont"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01794988"
    },
    {
      "nct_id": "NCT02620579",
      "title": "Biopsychosocial Influence on Shoulder Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Shoulder Pain"
      ],
      "interventions": [
        {
          "name": "Propranolol LA (60 mg)",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Shoulder Anatomy Education",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pain Processing Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 264,
      "start_date": "2016-01",
      "completion_date": "2021-11-05",
      "has_results": true,
      "last_update_posted_date": "2023-01-13",
      "last_synced_at": "2026-09-05T20:14:03.140Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02620579"
    },
    {
      "nct_id": "NCT07290361",
      "title": "Stratified Targeted Engagement From Primary Care to Physical Therapy (STEPPT)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain",
        "Neck Pain"
      ],
      "interventions": [
        {
          "name": "Engagement of clinic leadership (System Intervention - Usual Care)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Engagement of clinic leadership (System Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Registry (System Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Delivery of Patient Education Materials (System Intervention - Usual Care)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Delivery of Patient Education Materials (System Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Referral Specialist Training (System Intervention - Usual Care)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Health Navigator Training (System Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Care Navigation (System Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Care navigation audit and feedback (System Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Primary Care Provider training (Provider Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nurse/Medical Assistant Training (Provider Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Provider feedback on PT referral and adherence (Provider Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient education on spine pain condition (Patient Intervention - Usual Care)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient education on spine pain condition (Patient Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Education on Physical Referral by Providers (Patient Intervention - Usual Care)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Education on Physical Referral by Providers (Patient Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Electronic Patient Education on Physical Therapy Referral (Patient Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient education on physical therapy referral by Referral Specialist (Patient Intervention - Usual Care)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient education on physical therapy referral by Patient Health Navigator (Patient Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Care Navigation (System Intervention - Usual Care)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Monitoring of PT referral and adherence rates (System Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Monitoring of PT referral and adherence rates (System intervention - Usual Care)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "San Diego State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 17587,
      "start_date": "2025-12-01",
      "completion_date": "2029-02-28",
      "has_results": false,
      "last_update_posted_date": "2026-08-14",
      "last_synced_at": "2026-09-05T20:14:03.140Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07290361"
    },
    {
      "nct_id": "NCT01860950",
      "title": "Effects of Transcranial Direct Current Stimulation on Pain Perception",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "anodal tDCS",
          "type": "DEVICE"
        },
        {
          "name": "cathodal tDCS",
          "type": "DEVICE"
        },
        {
          "name": "sham tDCS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 79,
      "start_date": "2012-10",
      "completion_date": "2016-06",
      "has_results": true,
      "last_update_posted_date": "2018-12-04",
      "last_synced_at": "2026-09-05T20:14:03.140Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01860950"
    },
    {
      "nct_id": "NCT04275830",
      "title": "The Effects of Heart Rate Variability Biofeedback Training on Hematopoietic Cell Transplantation Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hematopoietic Stem Cell Transplantation",
        "Bone Marrow Transplant",
        "Heart Rate Variability",
        "Autonomic Nervous System",
        "Stress",
        "Mood",
        "Psychological Distress",
        "Emotion Regulation",
        "Communication Research",
        "Narrative"
      ],
      "interventions": [
        {
          "name": "Baseline Surveys",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Heart rate variability biofeedback",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Heart rate variability waitlist and Digital storytelling Control intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Arizona State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2020-02-04",
      "completion_date": "2022-02-04",
      "has_results": false,
      "last_update_posted_date": "2022-05-23",
      "last_synced_at": "2026-09-05T20:14:03.140Z",
      "location_count": 1,
      "location_summary": "Scottsdale, Arizona",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04275830"
    },
    {
      "nct_id": "NCT05127616",
      "title": "EPPIC: Easing Pelvic Pain Interventions Clinical Research Program",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Urologic Chronic Pelvic Pain Syndrome (UCPPS)",
        "Interstitial Cystitis",
        "Bladder Pain Syndrome",
        "Chronic Prostatitis",
        "Chronic Pain",
        "Chronic Pelvic Pain Syndrome",
        "Chronic Overlapping Pain Disorders"
      ],
      "interventions": [
        {
          "name": "Minimal Contact-Cognitive Behavior Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Education/Support",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "State University of New York at Buffalo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 240,
      "start_date": "2022-08-10",
      "completion_date": "2028-07-31",
      "has_results": false,
      "last_update_posted_date": "2026-01-26",
      "last_synced_at": "2026-09-05T20:14:03.140Z",
      "location_count": 3,
      "location_summary": "Los Angeles, California • Ann Arbor, Michigan • Buffalo, New York",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05127616"
    },
    {
      "nct_id": "NCT05050409",
      "title": "SMART Embedded Intervention for Military Postsurgical Engagement Readiness",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Pain Chronic"
      ],
      "interventions": [
        {
          "name": "Brief mindfulness",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mindfulness-Oriented Recovery Enhancement (MORE)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2022-05-01",
      "completion_date": "2027-10",
      "has_results": false,
      "last_update_posted_date": "2025-03-27",
      "last_synced_at": "2026-09-05T20:14:03.140Z",
      "location_count": 1,
      "location_summary": "Fort Sam Houston, Texas",
      "locations": [
        {
          "city": "Fort Sam Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05050409"
    },
    {
      "nct_id": "NCT05480904",
      "title": "Characterizing Sleep Among Long-term Survivors of Childhood Cancer",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "ALL, Adult",
        "CNS Tumor",
        "Solid Tumor"
      ],
      "interventions": [
        {
          "name": "Neurocognitive (Thinking) Testing",
          "type": "OTHER"
        },
        {
          "name": "CNS Vital Signs (Thinking) Testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Health Questionnaires, Sleep Surveys & Sleep Diary",
          "type": "OTHER"
        },
        {
          "name": "Echocardiography/EKG",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Pulmonary Function",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Remote Polysomnography",
          "type": "DEVICE"
        },
        {
          "name": "Physical Function",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIAGNOSTIC_TEST",
        "DEVICE"
      ],
      "sponsor": "St. Jude Children's Research Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 199,
      "start_date": "2023-04-17",
      "completion_date": "2027-01",
      "has_results": false,
      "last_update_posted_date": "2026-08-19",
      "last_synced_at": "2026-09-05T20:14:03.140Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05480904"
    }
  ]
}