{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Paired+Vagus+Nerve+Stimulation",
    "query": {
      "intervention": "Paired Vagus Nerve Stimulation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 41,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Paired+Vagus+Nerve+Stimulation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-22T14:26:03.034Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06543277",
      "title": "Safety and Feasibility of Paired Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) With Upper Limb Rehabilitation in Incomplete Spinal Cord Injury",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Incomplete Cervical Spinal Cord Injury (SCI)"
      ],
      "interventions": [
        {
          "name": "Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2025-08-15",
      "completion_date": "2027-12-30",
      "has_results": false,
      "last_update_posted_date": "2025-09-19",
      "last_synced_at": "2026-09-22T14:26:03.034Z",
      "location_count": 2,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06543277"
    },
    {
      "nct_id": "NCT04256837",
      "title": "Effect of Transcutaneous Electrical Auricular Stimulation of the Vagus Nerve in Kidney Transplant Recipients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vagus Nerve Stimulation"
      ],
      "interventions": [
        {
          "name": "Transcutaneous electrical auricular vagus nerve stimulation (VNS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Northwell Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 47,
      "start_date": "2020-01-13",
      "completion_date": "2021-01-07",
      "has_results": false,
      "last_update_posted_date": "2022-12-14",
      "last_synced_at": "2026-09-22T14:26:03.034Z",
      "location_count": 1,
      "location_summary": "Manhasset, New York",
      "locations": [
        {
          "city": "Manhasset",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04256837"
    },
    {
      "nct_id": "NCT03131960",
      "title": "Pivotal Study of VNS During Rehab After Stroke (VNS-REHAB)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cerebrovascular Stroke",
        "Upper Extremity Paresis"
      ],
      "interventions": [
        {
          "name": "Paired Vagus Nerve Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Rehabilitation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "MicroTransponder Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "22 Years to 80 Years"
      },
      "enrollment_count": 108,
      "start_date": "2017-07-01",
      "completion_date": "2022-06-30",
      "has_results": true,
      "last_update_posted_date": "2022-07-20",
      "last_synced_at": "2026-09-22T14:26:03.034Z",
      "location_count": 15,
      "location_summary": "Scottsdale, Arizona • Downey, California • Santa Monica, California + 12 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Downey",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03131960"
    },
    {
      "nct_id": "NCT06512194",
      "title": "Investigation to Understand and Optimize Psilocybin",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Depression"
      ],
      "interventions": [
        {
          "name": "Psilocybin",
          "type": "DRUG"
        },
        {
          "name": "Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)",
          "type": "DEVICE"
        },
        {
          "name": "Sham taVNS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Charles Raison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 141,
      "start_date": "2025-05-13",
      "completion_date": "2029-05",
      "has_results": false,
      "last_update_posted_date": "2026-08-10",
      "last_synced_at": "2026-09-22T14:26:03.034Z",
      "location_count": 1,
      "location_summary": "Edwards, Colorado",
      "locations": [
        {
          "city": "Edwards",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06512194"
    },
    {
      "nct_id": "NCT05301140",
      "title": "Vivistim Registry for Paired VNS Therapy (GRASP)",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Upper Extremity Problem"
      ],
      "interventions": [
        {
          "name": "Vivistim System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "MicroTransponder Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2023-03-15",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-29",
      "last_synced_at": "2026-09-22T14:26:03.034Z",
      "location_count": 15,
      "location_summary": "Orlando, Florida • Elk Grove Village, Illinois • Evanston, Illinois + 11 more",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Elk Grove Village",
          "state": "Illinois"
        },
        {
          "city": "Evanston",
          "state": "Illinois"
        },
        {
          "city": "Kansas City",
          "state": "Kansas"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05301140"
    },
    {
      "nct_id": "NCT06930716",
      "title": "Paired Vagus Nerve Stimulation in Mobilization of Patients With Prolonged Disorders of Consciousness",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Consciousness Disorders",
        "Brain Injury",
        "Altered Level of Consciousness"
      ],
      "interventions": [
        {
          "name": "Transcutaneous vagus nerve stimulation (taVNS)",
          "type": "DEVICE"
        },
        {
          "name": "Physical therapy using Hocoma",
          "type": "DEVICE"
        },
        {
          "name": "Standard of Care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2025-08-12",
      "completion_date": "2027-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-18",
      "last_synced_at": "2026-09-22T14:26:03.034Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06930716"
    },
    {
      "nct_id": "NCT06417385",
      "title": "taVNS-Paired Breastfeeding to Improve Breastfeeding at Discharge",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premature Birth",
        "Breastfeeding, Exclusive",
        "Feeding; Difficult, Newborn"
      ],
      "interventions": [
        {
          "name": "taVNS soterix device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Weeks",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "35 Weeks and older"
      },
      "enrollment_count": 10,
      "start_date": "2024-02-01",
      "completion_date": "2027-06-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-06",
      "last_synced_at": "2026-09-22T14:26:03.034Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06417385"
    },
    {
      "nct_id": "NCT06616831",
      "title": "At-Home taVNS - Stroke Rehab",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stroke",
        "Stroke, Ischemic",
        "Stroke Hemorrhagic"
      ],
      "interventions": [
        {
          "name": "Remote Transcutaneous Auricular Vagal Nerve Stimulation Paired with Task-Specific Training",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 5,
      "start_date": "2024-10-28",
      "completion_date": "2025-03-26",
      "has_results": true,
      "last_update_posted_date": "2026-08-13",
      "last_synced_at": "2026-09-22T14:26:03.034Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06616831"
    },
    {
      "nct_id": "NCT04064762",
      "title": "Targeted Plasticity Therapy for Posttraumatic Stress Disorder",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post Traumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Paired Vagus Nerve Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Baylor Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 9,
      "start_date": "2020-12-16",
      "completion_date": "2024-04",
      "has_results": false,
      "last_update_posted_date": "2023-01-05",
      "last_synced_at": "2026-09-22T14:26:03.034Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04064762"
    },
    {
      "nct_id": "NCT06288217",
      "title": "Non-invasive Trigeminal and Vagus Nerve Stimulation for Stroke Subjects With Chronic Upper Extremity Deficits",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Upper Extremity Paresis",
        "Stroke, Chronic"
      ],
      "interventions": [
        {
          "name": "NeuraStasis Stimulator System (Non-Invasive Trigeminal and Vagus Nerve Stimulation)",
          "type": "DEVICE"
        },
        {
          "name": "Upper Limb Rehabilitation",
          "type": "OTHER"
        },
        {
          "name": "Sham Stimulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "NeuraStasis, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "30 Years to 85 Years"
      },
      "enrollment_count": 16,
      "start_date": "2024-03-05",
      "completion_date": "2025-11-13",
      "has_results": false,
      "last_update_posted_date": "2026-06-02",
      "last_synced_at": "2026-09-22T14:26:03.034Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06288217"
    }
  ]
}