{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Palonosetron&page=2", "query": { "intervention": "Palonosetron", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Palonosetron&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-28T13:23:43.762Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03367572", "title": "Treatment of Refractory Nausea and Vomiting in Patients With Breast Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Breast Carcinoma" ], "interventions": [ { "name": "Dexamethasone", "type": "DRUG" }, { "name": "Laboratory Biomarker Analysis", "type": "OTHER" }, { "name": "Netupitant/Palonosetron Hydrochloride", "type": "DRUG" }, { "name": "Olanzapine", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" }, { "name": "Prochlorperazine", "type": "DRUG" }, { "name": "Quality-of-Life Assessment", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of Rochester NCORP Research Base", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 1363, "start_date": "2018-04-19", "completion_date": "2024-04-13", "has_results": true, "last_update_posted_date": "2025-09-25", "last_synced_at": "2026-09-28T13:23:43.762Z", "location_count": 18, "location_summary": "Honolulu, Hawaii • Decatur, Illinois • New Orleans, Louisiana + 15 more", "locations": [ { "city": "Honolulu", "state": "Hawaii" }, { "city": "Decatur", "state": "Illinois" }, { "city": "New Orleans", "state": "Louisiana" }, { "city": "Ann Arbor", "state": "Michigan" }, { "city": "Grand Rapids", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT03367572" }, { "nct_id": "NCT02517021", "title": "A Safety Study of Intravenous Pro-Netupitant and Palonosetron Combination for the Prevention of Nausea and Vomiting", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chemotherapy-Induced Nausea and Vomiting" ], "interventions": [ { "name": "Pro-netupitant/Palonosetron", "type": "DRUG" }, { "name": "Netupitant/Palonosetron", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Helsinn Healthcare SA", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 405, "start_date": "2015-11", "completion_date": "2016-08", "has_results": true, "last_update_posted_date": "2018-06-20", "last_synced_at": "2026-09-28T13:23:43.762Z", "location_count": 11, "location_summary": "Santa Monica, California • Whittier, California • Grand Junction, Colorado + 8 more", "locations": [ { "city": "Santa Monica", "state": "California" }, { "city": "Whittier", "state": "California" }, { "city": "Grand Junction", "state": "Colorado" }, { "city": "Miami", "state": "Florida" }, { "city": "Peoria", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT02517021" }, { "nct_id": "NCT01339260", "title": "An Efficacy and Safety Study of Oral Netupitant and Palonosetron for the Prevention of Nausea and Vomiting", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chemotherapy-Induced Nausea and Vomiting" ], "interventions": [ { "name": "Netupitant and Palonosetron", "type": "DRUG" }, { "name": "Palonosetron", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Helsinn Healthcare SA", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1455, "start_date": "2011-04", "completion_date": null, "has_results": true, "last_update_posted_date": "2014-11-26", "last_synced_at": "2026-09-28T13:23:43.762Z", "location_count": 28, "location_summary": "Anniston, Alabama • Muscle Shoals, Alabama • Hot Springs, Arkansas + 24 more", "locations": [ { "city": "Anniston", "state": "Alabama" }, { "city": "Muscle Shoals", "state": "Alabama" }, { "city": "Hot Springs", "state": "Arkansas" }, { "city": "Corona", "state": "California" }, { "city": "Fountain Valley", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01339260" }, { "nct_id": "NCT01395901", "title": "Safety and Efficacy of Palonosetron IV to Prevent Postoperative Nausea and Vomiting in Pediatric Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Postoperative Nausea and Vomiting" ], "interventions": [ { "name": "Palonosetron", "type": "DRUG" }, { "name": "Ondansetron", "type": "DRUG" }, { "name": "Placebo to Ondansetron", "type": "DRUG" }, { "name": "Placebo to Palonosetron", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Helsinn Healthcare SA", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "16 Years", "sex": "ALL", "summary": "Up to 16 Years" }, "enrollment_count": 670, "start_date": "2011-06", "completion_date": "2012-04", "has_results": true, "last_update_posted_date": "2014-07-30", "last_synced_at": "2026-09-28T13:23:43.762Z", "location_count": 12, "location_summary": "Florence, Alabama • Sheffield, Alabama • Washington D.C., District of Columbia + 9 more", "locations": [ { "city": "Florence", "state": "Alabama" }, { "city": "Sheffield", "state": "Alabama" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Miami", "state": "Florida" }, { "city": "Shreveport", "state": "Louisiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT01395901" }, { "nct_id": "NCT03578081", "title": "Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic Chemotherapy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Malignant Neoplasm" ], "interventions": [ { "name": "Palonosetron Hydrochloride", "type": "DRUG" }, { "name": "Ondansetron Hydrochloride", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" }, { "name": "Fosaprepitant Dimeglumine", "type": "DRUG" }, { "name": "Olanzapine", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Alliance for Clinical Trials in Oncology", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 690, "start_date": "2018-11-20", "completion_date": "2023-05-01", "has_results": true, "last_update_posted_date": "2025-04-06", "last_synced_at": "2026-09-28T13:23:43.762Z", "location_count": 565, "location_summary": "Birmingham, Alabama • Fairbanks, Alaska • Kingman, Arizona + 372 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Fairbanks", "state": "Alaska" }, { "city": "Kingman", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT03578081" }, { "nct_id": "NCT00381862", "title": "Phase II Trial of Aprepitant & Palonosetron for CINV Prevention w FOLFOX", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Colorectal Cancer", "Nausea and Vomiting" ], "interventions": [ { "name": "aprepitant", "type": "DRUG" }, { "name": "dexamethasone", "type": "DRUG" }, { "name": "fluorouracil", "type": "DRUG" }, { "name": "irinotecan hydrochloride", "type": "DRUG" }, { "name": "leucovorin calcium", "type": "DRUG" }, { "name": "oxaliplatin", "type": "DRUG" }, { "name": "palonosetron hydrochloride", "type": "DRUG" }, { "name": "quality-of-life assessment", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "OHSU Knight Cancer Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "120 Years", "sex": "ALL", "summary": "18 Years to 120 Years" }, "enrollment_count": 54, "start_date": "2006-06", "completion_date": "2008-07", "has_results": true, "last_update_posted_date": "2017-06-12", "last_synced_at": "2026-09-28T13:23:43.762Z", "location_count": 6, "location_summary": "Savannah, Georgia • Hilo, Hawaii • Harvey, Illinois + 3 more", "locations": [ { "city": "Savannah", "state": "Georgia" }, { "city": "Hilo", "state": "Hawaii" }, { "city": "Harvey", "state": "Illinois" }, { "city": "Kansas City", "state": "Missouri" }, { "city": "Portland", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT00381862" }, { "nct_id": "NCT05199818", "title": "Buccal Film vs IV Palonosetron for Prevention of CINV in Cancer Patients Receiving MEC", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chemotherapy-induced Nausea and Vomiting" ], "interventions": [ { "name": "Palonosetron HCl Buccal Film 0.5 mg", "type": "DRUG" }, { "name": "IV Palonosetron 0.25 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Xiamen LP Pharmaceutical Co., Ltd", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 328, "start_date": "2022-03-01", "completion_date": "2023-11", "has_results": false, "last_update_posted_date": "2023-01-20", "last_synced_at": "2026-09-28T13:23:43.762Z", "location_count": 13, "location_summary": "Chandler, Arizona • Anaheim, California • Lakeland, Florida + 9 more", "locations": [ { "city": "Chandler", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Lakeland", "state": "Florida" }, { "city": "Miami Lakes", "state": "Florida" }, { "city": "Ocala", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05199818" }, { "nct_id": "NCT01376297", "title": "A Safety Study of Oral Netupitant and Palonosetron for the Prevention of Nausea and Vomiting", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chemotherapy-Induced Nausea and Vomiting" ], "interventions": [ { "name": "Netupitant and Palonosetron", "type": "DRUG" }, { "name": "Aprepitant", "type": "DRUG" }, { "name": "Palonosetron", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Helsinn Healthcare SA", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 413, "start_date": "2011-07", "completion_date": null, "has_results": true, "last_update_posted_date": "2014-11-17", "last_synced_at": "2026-09-28T13:23:43.762Z", "location_count": 11, "location_summary": "Muscle Shoals, Alabama • Burbank, California • Los Angeles, California + 8 more", "locations": [ { "city": "Muscle Shoals", "state": "Alabama" }, { "city": "Burbank", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "East Orange", "state": "New Jersey" }, { "city": "Nyack", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01376297" }, { "nct_id": "NCT02625181", "title": "Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Postoperative Nausea and Vomiting" ], "interventions": [ { "name": "Automated recommendation at the start of the case", "type": "PROCEDURE" }, { "name": "Automated notification at the start of surgery", "type": "PROCEDURE" }, { "name": "Preoperative recommendations: by email", "type": "PROCEDURE" }, { "name": "Automated notification at the end of surgery", "type": "PROCEDURE" }, { "name": "Anesthesia Information Management System (AIMS)", "type": "DEVICE" }, { "name": "Perioperative Data Warehouse (PDW)", "type": "DEVICE" }, { "name": "General anesthesia", "type": "PROCEDURE" }, { "name": "Elective surgery", "type": "PROCEDURE" }, { "name": "Propofol", "type": "DRUG" }, { "name": "Sevoflurane", "type": "DRUG" }, { "name": "Isoflurane", "type": "DRUG" }, { "name": "Desflurane", "type": "DRUG" }, { "name": "Scopolamine", "type": "DRUG" }, { "name": "Droperidol", "type": "DRUG" }, { "name": "Haloperidol", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" }, { "name": "Promethazine", "type": "DRUG" }, { "name": "Meclizine", "type": "DRUG" }, { "name": "Aprepitant", "type": "DRUG" }, { "name": "Metoclopramide", "type": "DRUG" }, { "name": "Fentanyl", "type": "DRUG" }, { "name": "Sufentanil", "type": "DRUG" }, { "name": "Alfentanil", "type": "DRUG" }, { "name": "Remifentanil", "type": "DRUG" }, { "name": "Morphine", "type": "DRUG" }, { "name": "Meperidine", "type": "DRUG" }, { "name": "Hydromorphone", "type": "DRUG" }, { "name": "Methadone", "type": "DRUG" }, { "name": "Oxycodone", "type": "DRUG" }, { "name": "Oxymorphone", "type": "DRUG" }, { "name": "Hydrocodone", "type": "DRUG" }, { "name": "Ketamine", "type": "DRUG" }, { "name": "Ondansetron", "type": "DRUG" }, { "name": "Granisetron", "type": "DRUG" }, { "name": "Dolasetron mesylate", "type": "DRUG" }, { "name": "Palonosetron", "type": "DRUG" }, { "name": "Tropisetron", "type": "DRUG" }, { "name": "Ramosetron", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "DEVICE", "DRUG" ], "sponsor": "Vanderbilt University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 27034, "start_date": "2016-07", "completion_date": "2017-11-30", "has_results": true, "last_update_posted_date": "2019-03-07", "last_synced_at": "2026-09-28T13:23:43.762Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT02625181" }, { "nct_id": "NCT00903396", "title": "Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy in Patients With Primary Abdominal Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Anal Cancer", "Carcinoma of the Appendix", "Colorectal Cancer", "Extrahepatic Bile Duct Cancer", "Gallbladder Cancer", "Gastric Cancer", "Gastrointestinal Carcinoid Tumor", "Liver Cancer", "Nausea and Vomiting", "Pancreatic Cancer", "Primary Peritoneal Cavity Cancer", "Small Intestine Cancer" ], "interventions": [ { "name": "palonosetron hydrochloride", "type": "DRUG" }, { "name": "placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Alliance for Clinical Trials in Oncology", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 7, "start_date": "2009-09", "completion_date": "2013-05", "has_results": true, "last_update_posted_date": "2017-11-24", "last_synced_at": "2026-09-28T13:23:43.762Z", "location_count": 69, "location_summary": "Scottsdale, Arizona • Jacksonville, Florida • Moline, Illinois + 37 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Moline", "state": "Illinois" }, { "city": "Moline", "state": "Illinois" }, { "city": "Elkhart", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT00903396" } ] }