{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pancreatic+Clamp+Study", "query": { "intervention": "Pancreatic Clamp Study" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 35, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pancreatic+Clamp+Study&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-06T14:16:25.636Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT07778524", "title": "Alpelisib Challenge Test (ACT)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Insulin Resistance", "Type 2 Diabetes", "Obesity & Overweight", "Healthy Adult Participants" ], "interventions": [ { "name": "Alpelisib 300 mg", "type": "DRUG" }, { "name": "Alpelisib Challenge Test (ACT): Mixed Meal Tolerance Test (MMTT) after taking alpelisib", "type": "DIAGNOSTIC_TEST" }, { "name": "Hyperglycemic clamp", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DRUG", "DIAGNOSTIC_TEST" ], "sponsor": "Columbia University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 15, "start_date": "2026-09-02", "completion_date": "2028-08-31", "has_results": false, "last_update_posted_date": "2026-09-03", "last_synced_at": "2026-09-06T14:16:25.636Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT07778524" }, { "nct_id": "NCT03540758", "title": "Regulation of Endogenous Glucose Production by Central KATP Channels", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Diabetes Mellitus", "Glucose Metabolism Disorders" ], "interventions": [ { "name": "Diazoxide", "type": "DRUG" }, { "name": "Nicotinic acid", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Albert Einstein College of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "21 Years to 70 Years" }, "enrollment_count": 100, "start_date": "2018-08-01", "completion_date": "2027-04", "has_results": false, "last_update_posted_date": "2026-04-28", "last_synced_at": "2026-09-06T14:16:25.636Z", "location_count": 1, "location_summary": "The Bronx, New York", "locations": [ { "city": "The Bronx", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT03540758" }, { "nct_id": "NCT06126354", "title": "Dexamethasone/Pancreatic Clamp P&F", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Insulin Resistance", "Prediabetic State", "Non-Alcoholic Fatty Liver Disease", "Overweight and Obesity" ], "interventions": [ { "name": "Insulin human", "type": "DRUG" }, { "name": "Octreotide Acetate", "type": "DRUG" }, { "name": "Glucagon", "type": "DRUG" }, { "name": "Human Growth Hormone", "type": "DRUG" }, { "name": "Dexamethasone Oral", "type": "DRUG" }, { "name": "[6,6-2H2] D-glucose", "type": "OTHER" }, { "name": "20% D-glucose (aq)", "type": "DRUG" }, { "name": "BOOST Plus", "type": "DIETARY_SUPPLEMENT" }, { "name": "Harvard Apparatus PHD ULTRA CP syringe pump", "type": "DEVICE" }, { "name": "Yellow Springs Instruments (YSI) 2500 Biochemistry Glucose/Lactate Analyzer", "type": "DEVICE" }, { "name": "Normal saline", "type": "OTHER" }, { "name": "Human albumin", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER", "DIETARY_SUPPLEMENT", "DEVICE" ], "sponsor": "Columbia University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 0, "start_date": "2024-07-01", "completion_date": "2026-03-31", "has_results": false, "last_update_posted_date": "2024-07-10", "last_synced_at": "2026-09-06T14:16:25.636Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT06126354" }, { "nct_id": "NCT05724134", "title": "Pancreatic Clamp in NAFLD", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Insulin Resistance", "Prediabetic State", "Hyperinsulinemia", "Non-Alcoholic Fatty Liver Disease", "Obesity" ], "interventions": [ { "name": "Insulin human", "type": "DRUG" }, { "name": "Octreotide Acetate", "type": "DRUG" }, { "name": "Glucagon", "type": "DRUG" }, { "name": "Growth Hormone, Human", "type": "DRUG" }, { "name": "[6,6-2H2] D-glucose", "type": "OTHER" }, { "name": "20% D-glucose (aq)", "type": "DRUG" }, { "name": "BOOST Plus", "type": "DIETARY_SUPPLEMENT" }, { "name": "CORE Bar", "type": "DIETARY_SUPPLEMENT" }, { "name": "Harvard Apparatus PHD ULTRA CP syringe pump", "type": "DEVICE" }, { "name": "Yellow Springs Instruments (YSI) 2500 Biochemistry Glucose/Lactate Analyzer", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "OTHER", "DIETARY_SUPPLEMENT", "DEVICE" ], "sponsor": "Columbia University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 18, "start_date": "2023-08-29", "completion_date": "2025-09-24", "has_results": false, "last_update_posted_date": "2026-01-12", "last_synced_at": "2026-09-06T14:16:25.636Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT05724134" }, { "nct_id": "NCT05184868", "title": "AT247, NovoLog® and Fiasp® Administered Via Continuous Subcutaneous Infusion in Glucose Clamp Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Diabetes Mellitus, Type 1" ], "interventions": [ { "name": "AT247", "type": "DRUG" }, { "name": "NovoLog", "type": "DRUG" }, { "name": "Fiasp", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Arecor Limited", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 24, "start_date": "2022-01-03", "completion_date": "2022-09-09", "has_results": false, "last_update_posted_date": "2022-09-13", "last_synced_at": "2026-09-06T14:16:25.636Z", "location_count": 1, "location_summary": "Chula Vista, California", "locations": [ { "city": "Chula Vista", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05184868" }, { "nct_id": "NCT05500586", "title": "The Effects of Glucagon on Hepatic Metabolism", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Obesity", "Type2diabetes", "NAFLD" ], "interventions": [ { "name": "Glucagon response study", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Adrian Vella", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "25 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "25 Years to 65 Years" }, "enrollment_count": 21, "start_date": "2022-10-20", "completion_date": "2026-03-31", "has_results": false, "last_update_posted_date": "2026-04-29", "last_synced_at": "2026-09-06T14:16:25.636Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT05500586" }, { "nct_id": "NCT07212868", "title": "The Role of Glucagon in Glucose Metabolism in Humans With and Without Bariatric Surgery", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Non-Diabetic" ], "interventions": [ { "name": "REMD-477 versus Placebo", "type": "DRUG" }, { "name": "Exogenous glucagon versus saline infusion", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "The University of Texas Health Science Center at San Antonio", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 150, "start_date": "2026-02-25", "completion_date": "2030-06-30", "has_results": false, "last_update_posted_date": "2026-05-11", "last_synced_at": "2026-09-06T14:16:25.636Z", "location_count": 2, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT07212868" }, { "nct_id": "NCT02971202", "title": "Contribution of Hyperinsulinemia vs. Hyperglycemia to Insulin Resistance in Type 1 Diabetes and Maturity Onset Diabetes of the Young, Type 2 (MODY2)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Type 1 Diabetes Mellitus", "Maturity-Onset Diabetes of the Young, Type 2", "MODY2", "Insulin Resistance" ], "interventions": [ { "name": "Hyperinsulinemic, euglycemic clamp", "type": "DRUG" }, { "name": "20% dextrose", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vanderbilt University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "13 Years", "maximum_age": "51 Years", "sex": "ALL", "summary": "13 Years to 51 Years" }, "enrollment_count": 33, "start_date": "2016-12", "completion_date": "2019-02", "has_results": true, "last_update_posted_date": "2019-08-01", "last_synced_at": "2026-09-06T14:16:25.636Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT02971202" }, { "nct_id": "NCT00719108", "title": "Comparative Glucose Clamp Study of Wockhardt's Insulin Human Regular for Injection and Actrapid, in Healthy Subjects.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Diabetes" ], "interventions": [ { "name": "Wosulin R", "type": "BIOLOGICAL" }, { "name": "Actrapid", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Wockhardt", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "18 Years to 45 Years" }, "enrollment_count": 42, "start_date": "2008-07", "completion_date": "2008-09", "has_results": false, "last_update_posted_date": "2012-12-27", "last_synced_at": "2026-09-06T14:16:25.636Z", "location_count": 1, "location_summary": "Chula Vista, California", "locations": [ { "city": "Chula Vista", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00719108" }, { "nct_id": "NCT03998709", "title": "Effect of Fasting Free Fatty Acids and Fasting Glucose on 1st and 2nd Phase Insulin Secretion", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Somatostatin", "type": "DRUG" }, { "name": "Dextrose", "type": "OTHER" }, { "name": "Insulin", "type": "DRUG" }, { "name": "Intralipid", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "25 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "25 Years to 65 Years" }, "enrollment_count": 0, "start_date": "2020-02-01", "completion_date": "2022-07-31", "has_results": false, "last_update_posted_date": "2022-09-09", "last_synced_at": "2026-09-06T14:16:25.636Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT03998709" } ] }