{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pancreatic+Clamp+Study&page=2", "query": { "intervention": "Pancreatic Clamp Study", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pancreatic+Clamp+Study&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-27T23:04:44.207Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03170544", "title": "Single Ascending Dose Study of MK-1092 in Healthy Participants and in Participants With Type 1 and Type 2 Diabetes Mellitus (MK-1092-001)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Type 1 Diabetes Mellitus", "Type 2 Diabetes Mellitus" ], "interventions": [ { "name": "MK-1092, 4.0 nmol/kg", "type": "DRUG" }, { "name": "MK-1092, 8.0 nmol/kg", "type": "DRUG" }, { "name": "MK-1092, 16 nmol/kg", "type": "DRUG" }, { "name": "MK-1092, 32 nmol/kg", "type": "DRUG" }, { "name": "MK-1092, 64 nmol/kg", "type": "DRUG" }, { "name": "Glargine 3.0 nmol/kg", "type": "DRUG" }, { "name": "Lispro 1.2 nmol/kg", "type": "DRUG" }, { "name": "Placebo to glargine", "type": "DRUG" }, { "name": "Placebo to MK-1092", "type": "DRUG" }, { "name": "Dextrose", "type": "OTHER" }, { "name": "Insulin", "type": "BIOLOGICAL" } ], "intervention_types": [ "DRUG", "OTHER", "BIOLOGICAL" ], "sponsor": "Merck Sharp & Dohme LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 69, "start_date": "2017-08-16", "completion_date": "2018-11-08", "has_results": true, "last_update_posted_date": "2019-11-15", "last_synced_at": "2026-09-27T23:04:44.207Z", "location_count": 1, "location_summary": "Chula Vista, California", "locations": [ { "city": "Chula Vista", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03170544" }, { "nct_id": "NCT01311076", "title": "TAK-329 Glucose Clamp Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Type 1 Diabetes Mellitus" ], "interventions": [ { "name": "TAK-329", "type": "DRUG" }, { "name": "Insulin", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 37, "start_date": "2011-03", "completion_date": "2012-01", "has_results": false, "last_update_posted_date": "2012-02-13", "last_synced_at": "2026-09-27T23:04:44.207Z", "location_count": 1, "location_summary": "Chula Vista, California", "locations": [ { "city": "Chula Vista", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01311076" }, { "nct_id": "NCT00719108", "title": "Comparative Glucose Clamp Study of Wockhardt's Insulin Human Regular for Injection and Actrapid, in Healthy Subjects.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Diabetes" ], "interventions": [ { "name": "Wosulin R", "type": "BIOLOGICAL" }, { "name": "Actrapid", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Wockhardt", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "18 Years to 45 Years" }, "enrollment_count": 42, "start_date": "2008-07", "completion_date": "2008-09", "has_results": false, "last_update_posted_date": "2012-12-27", "last_synced_at": "2026-09-27T23:04:44.207Z", "location_count": 1, "location_summary": "Chula Vista, California", "locations": [ { "city": "Chula Vista", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00719108" }, { "nct_id": "NCT05500586", "title": "The Effects of Glucagon on Hepatic Metabolism", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Obesity", "Type2diabetes", "NAFLD" ], "interventions": [ { "name": "Glucagon response study", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Adrian Vella", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "25 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "25 Years to 65 Years" }, "enrollment_count": 21, "start_date": "2022-10-20", "completion_date": "2026-03-31", "has_results": false, "last_update_posted_date": "2026-04-29", "last_synced_at": "2026-09-27T23:04:44.207Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT05500586" }, { "nct_id": "NCT03998709", "title": "Effect of Fasting Free Fatty Acids and Fasting Glucose on 1st and 2nd Phase Insulin Secretion", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Somatostatin", "type": "DRUG" }, { "name": "Dextrose", "type": "OTHER" }, { "name": "Insulin", "type": "DRUG" }, { "name": "Intralipid", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "25 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "25 Years to 65 Years" }, "enrollment_count": 0, "start_date": "2020-02-01", "completion_date": "2022-07-31", "has_results": false, "last_update_posted_date": "2022-09-09", "last_synced_at": "2026-09-27T23:04:44.207Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT03998709" }, { "nct_id": "NCT00524472", "title": "Outcomes Study of Hyperinsulinemic Glucose Control in Cardiac Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cardiac Surgery" ], "interventions": [ { "name": "Hyperinsulinemic-normoglycemic clamp", "type": "OTHER" }, { "name": "insulin at the standard of care levels", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "The Cleveland Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 1439, "start_date": "2007-07", "completion_date": "2015-04", "has_results": true, "last_update_posted_date": "2018-10-26", "last_synced_at": "2026-09-27T23:04:44.207Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00524472" }, { "nct_id": "NCT06558422", "title": "Human Models of Selective Insulin Resistance: Pancreatic Clamp", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Insulin Resistance", "Hyperinsulinemia", "Metabolic Dysfunction Associated Steatotic Liver Disease", "Non-Alcoholic Fatty Liver Disease", "Prediabetic State", "Obesity" ], "interventions": [ { "name": "Insulin human", "type": "DRUG" }, { "name": "Octreotide Acetate", "type": "DRUG" }, { "name": "Glucagon", "type": "DRUG" }, { "name": "Growth Hormone, Human", "type": "DRUG" }, { "name": "20% D-glucose (aq)", "type": "DRUG" }, { "name": "[6,6-2H2] D-glucose", "type": "DIAGNOSTIC_TEST" }, { "name": "[1-13C1] sodium acetate", "type": "DIAGNOSTIC_TEST" }, { "name": "Nestle BOOST Plus", "type": "DIETARY_SUPPLEMENT" }, { "name": "KIND Bar", "type": "DIETARY_SUPPLEMENT" }, { "name": "Harvard Apparatus PHD ULTRA CP syringe pump", "type": "DEVICE" }, { "name": "Yellow Springs Instruments (YSI) 2500 Biochemistry Glucose/Lactate Analyzer", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DIAGNOSTIC_TEST", "DIETARY_SUPPLEMENT", "DEVICE" ], "sponsor": "Columbia University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 36, "start_date": "2027-01-01", "completion_date": "2029-02-28", "has_results": false, "last_update_posted_date": "2026-02-06", "last_synced_at": "2026-09-27T23:04:44.207Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT06558422" }, { "nct_id": "NCT02535715", "title": "A Euglycemic Insulin Clamp Study in Type 1 Diabetic Patients With Oral Insulin (ORAMED)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Type 1 Diabetes" ], "interventions": [ { "name": "ORMD-0801 capsules- 2x8mg", "type": "DRUG" }, { "name": "ORMD-0801 capsules- 3x8mg", "type": "DRUG" }, { "name": "ORMD-0801 capsules- 1x16mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The University of Texas Health Science Center at San Antonio", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 11, "start_date": "2015-01", "completion_date": "2017-04", "has_results": true, "last_update_posted_date": "2019-03-21", "last_synced_at": "2026-09-27T23:04:44.207Z", "location_count": 1, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02535715" }, { "nct_id": "NCT07778524", "title": "Alpelisib Challenge Test (ACT)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Insulin Resistance", "Type 2 Diabetes", "Obesity & Overweight", "Healthy Adult Participants" ], "interventions": [ { "name": "Alpelisib 300 mg", "type": "DRUG" }, { "name": "Alpelisib Challenge Test (ACT): Mixed Meal Tolerance Test (MMTT) after taking alpelisib", "type": "DIAGNOSTIC_TEST" }, { "name": "Hyperglycemic clamp", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DRUG", "DIAGNOSTIC_TEST" ], "sponsor": "Columbia University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 15, "start_date": "2026-09-02", "completion_date": "2028-08-31", "has_results": false, "last_update_posted_date": "2026-09-03", "last_synced_at": "2026-09-27T23:04:44.207Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT07778524" }, { "nct_id": "NCT00596063", "title": "Comparative Glucose Clamp Study of Wockhardt's Insulin Human Regular for Injection and Novolin R, in Healthy Subjects.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Diabetes Mellitus" ], "interventions": [ { "name": "Wosulin R", "type": "BIOLOGICAL" }, { "name": "Novolin R", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Wockhardt", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "18 Years to 45 Years" }, "enrollment_count": 25, "start_date": "2008-01", "completion_date": "2008-02", "has_results": false, "last_update_posted_date": "2012-12-27", "last_synced_at": "2026-09-27T23:04:44.207Z", "location_count": 2, "location_summary": "Chula Vista, California", "locations": [ { "city": "Chula Vista", "state": "California" }, { "city": "Chula Vista", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00596063" } ] }