{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Para-aminohippuric+Acid", "query": { "intervention": "Para-aminohippuric Acid" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 18, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Para-aminohippuric+Acid&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-30T11:00:18.298Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03618420", "title": "Copeptin in Adolescent Participants With Type 1 Diabetes and Early Renal Hemodynamic Function", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Diabetes Mellitus, Type 1", "Nephropathy", "Diabetic Nephropathies", "Juvenile Diabetes", "Diabetes Mellitus Complication", "Autoimmune Diabetes", "Type 1 Diabetes Mellitus" ], "interventions": [ { "name": "Aminohippurate Sodium Inj 20%", "type": "DRUG" }, { "name": "Iohexol Inj 300 mg/mL", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "21 Years", "sex": "ALL", "summary": "12 Years to 21 Years" }, "enrollment_count": 50, "start_date": "2018-10-01", "completion_date": "2021-08-01", "has_results": true, "last_update_posted_date": "2022-04-20", "last_synced_at": "2026-09-30T11:00:18.298Z", "location_count": 1, "location_summary": "Aurora, Colorado", "locations": [ { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT03618420" }, { "nct_id": "NCT05507892", "title": "Renal Mechanism of SGLT2 Inhibition", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Type 2 Diabetes", "Diabetic Kidney Disease" ], "interventions": [ { "name": "canagliflozin", "type": "DRUG" }, { "name": "Aminohippurate Sodium Inj 20%", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 45, "start_date": "2022-10-10", "completion_date": "2026-12-15", "has_results": false, "last_update_posted_date": "2026-06-02", "last_synced_at": "2026-09-30T11:00:18.298Z", "location_count": 2, "location_summary": "Aurora, Colorado • Ann Arbor, Michigan", "locations": [ { "city": "Aurora", "state": "Colorado" }, { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT05507892" }, { "nct_id": "NCT01456208", "title": "Genetic Mechanisms in Human Hypertension", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Para-aminohippuric Acid", "type": "DRUG" }, { "name": "Angiotensin II", "type": "DRUG" }, { "name": "Norepinephrine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 150, "start_date": "1999-10", "completion_date": "2020-06", "has_results": false, "last_update_posted_date": "2021-05-12", "last_synced_at": "2026-09-30T11:00:18.298Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01456208" }, { "nct_id": "NCT01241669", "title": "Randomized, Placebo-controlled Study to Evaluate Effects of E5555 on Renal Function Parameters and OCT2 Activity", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy Subjects" ], "interventions": [ { "name": "E5555", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eisai Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 104, "start_date": "2010-10", "completion_date": null, "has_results": false, "last_update_posted_date": "2014-07-11", "last_synced_at": "2026-09-30T11:00:18.298Z", "location_count": 1, "location_summary": "Overland Park, Kansas", "locations": [ { "city": "Overland Park", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01241669" }, { "nct_id": "NCT04407481", "title": "PErfusioN, OxyGen ConsUmptIon and ENergetics in ADPKD (PENGUIN)", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Polycystic Kidney Disease, Adult", "Polycystic Kidney, Autosomal Dominant" ], "interventions": [ { "name": "Aminohippurate Sodium Inj 20%", "type": "DRUG" }, { "name": "Iohexol Inj 300 milligrams per milliliter (MG/ML)", "type": "DRUG" }, { "name": "PET/CT Scan", "type": "RADIATION" } ], "intervention_types": [ "DRUG", "RADIATION" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "40 Years", "sex": "ALL", "summary": "18 Years to 40 Years" }, "enrollment_count": 22, "start_date": "2020-11-01", "completion_date": "2022-10-13", "has_results": false, "last_update_posted_date": "2023-02-03", "last_synced_at": "2026-09-30T11:00:18.298Z", "location_count": 1, "location_summary": "Aurora, Colorado", "locations": [ { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT04407481" }, { "nct_id": "NCT03620773", "title": "Impact of Metabolic Surgery on Pancreatic, Renal and Cardiovascular Health in Youth With Type 2 Diabetes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Type 2 Diabetes Mellitus", "Obesity", "Bariatric Surgery Candidate", "Nephropathy", "Diabetic Kidney Disease", "Diabetes Mellitus, Type 2", "Diabetes Mellitus", "Diabetes Complications", "Weight Loss", "Diabetic Nephropathies", "Adolescent Obesity", "Pediatric Obesity" ], "interventions": [ { "name": "Aminohippurate Sodium Inj 20%", "type": "DRUG" }, { "name": "Iohexol Inj 300 mg/mL", "type": "DRUG" }, { "name": "Vertical Sleeve Gastrectomy", "type": "PROCEDURE" }, { "name": "Renal Biopsy", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "21 Years", "sex": "ALL", "summary": "12 Years to 21 Years" }, "enrollment_count": 24, "start_date": "2018-10-01", "completion_date": "2024-09-25", "has_results": false, "last_update_posted_date": "2026-01-12", "last_synced_at": "2026-09-30T11:00:18.298Z", "location_count": 1, "location_summary": "Aurora, Colorado", "locations": [ { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT03620773" }, { "nct_id": "NCT05319990", "title": "Pathogenesis of Kidney Disease in Type 1 Diabetes: a Modern Kidney Biopsy Cohort (The PANDA Study)", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Type 1 Diabetes", "Diabetic Kidney Disease", "Diabetes Complications", "Diabetic Nephropathies", "Autoimmune Diabetes" ], "interventions": [ { "name": "Aminohippurate Sodium Inj 20% Diagnostic aid/agent used to measure effective renal plasma flow (ERPF)", "type": "DRUG" }, { "name": "Iohexol Inj 300 MG/ML Diagnostic aid/agent used to measure glomerular filtration rate (GFR)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 100, "start_date": "2022-03-09", "completion_date": "2027-12-31", "has_results": false, "last_update_posted_date": "2026-05-22", "last_synced_at": "2026-09-30T11:00:18.298Z", "location_count": 1, "location_summary": "Aurora, Colorado", "locations": [ { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT05319990" }, { "nct_id": "NCT01426529", "title": "Caveolin-1 and Vascular Dysfunction", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Hypertension", "Insulin Resistance" ], "interventions": [ { "name": "Para-aminohippuric Acid", "type": "DRUG" }, { "name": "Angiotensin II", "type": "DRUG" }, { "name": "Norepinephrine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 120, "start_date": "2010-10-01", "completion_date": "2026-10-15", "has_results": false, "last_update_posted_date": "2025-12-08", "last_synced_at": "2026-09-30T11:00:18.298Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01426529" }, { "nct_id": "NCT01511042", "title": "Vascular Dysfunction in Diabetes: Genes and Hormones", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Diabetes Mellitus" ], "interventions": [ { "name": "Para-aminohippuric Acid", "type": "DRUG" }, { "name": "Angiotensin II", "type": "DRUG" }, { "name": "Norepinephrine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 100, "start_date": "1999-12", "completion_date": "2020-06", "has_results": false, "last_update_posted_date": "2022-11-09", "last_synced_at": "2026-09-30T11:00:18.298Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01511042" }, { "nct_id": "NCT04649229", "title": "Mechanisms Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 3", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Heart Failure" ], "interventions": [ { "name": "LCZ 696", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Para-aminohippurate", "type": "DRUG" }, { "name": "Iohexol", "type": "DRUG" }, { "name": "Aprepitant", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 46, "start_date": "2021-05-27", "completion_date": "2025-05-22", "has_results": false, "last_update_posted_date": "2026-03-17", "last_synced_at": "2026-09-30T11:00:18.298Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT04649229" } ] }