{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Paroxetine-CR", "query": { "intervention": "Paroxetine-CR" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 27, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Paroxetine-CR&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-09T21:25:22.395Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01360866", "title": "Safety and Tolerability of Oral OPC-34712 as Adjunctive Therapy in Adults With Major Depressive Disorder (the Orion Trial)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Depressive Disorder", "Depression", "Depressive Disorder, Major", "Mood Disorders", "Mental Disorders" ], "interventions": [ { "name": "OPC-34712", "type": "DRUG" }, { "name": "Escitalopram", "type": "DRUG" }, { "name": "Fluoxetine", "type": "DRUG" }, { "name": "Paroxetine CR", "type": "DRUG" }, { "name": "Sertraline", "type": "DRUG" }, { "name": "Duloxetine", "type": "DRUG" }, { "name": "Venlafaxine XR", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Otsuka Pharmaceutical Development & Commercialization, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 2944, "start_date": "2011-10", "completion_date": "2017-05-18", "has_results": true, "last_update_posted_date": "2018-09-17", "last_synced_at": "2026-09-09T21:25:22.395Z", "location_count": 93, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 90 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Costa Mesa", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01360866" }, { "nct_id": "NCT00749359", "title": "PAXIL CR Bioequivalence Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Depressive Disorder" ], "interventions": [ { "name": "Paxil CR", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 166, "start_date": "2008-07-07", "completion_date": "2008-09-16", "has_results": false, "last_update_posted_date": "2017-08-04", "last_synced_at": "2026-09-09T21:25:22.395Z", "location_count": 2, "location_summary": "Buffalo, New York • Tacoma, Washington", "locations": [ { "city": "Buffalo", "state": "New York" }, { "city": "Tacoma", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT00749359" }, { "nct_id": "NCT00647881", "title": "Food Study of Paroxetine Hydrochloride Controlled-Release Tablets 25 mg to Paxil CR™ Tablets 25 mg", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Paroxetine Hydrochloride Controlled-Release Tablets 25 mg", "type": "DRUG" }, { "name": "Paxil CR™ Tablets 25 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mylan Pharmaceuticals Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 75, "start_date": "2005-04", "completion_date": "2005-05", "has_results": false, "last_update_posted_date": "2024-04-24", "last_synced_at": "2026-09-09T21:25:22.395Z", "location_count": 1, "location_summary": "Fargo, North Dakota", "locations": [ { "city": "Fargo", "state": "North Dakota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00647881" }, { "nct_id": "NCT00330239", "title": "Paroxetine Treatment in Outpatients With Comorbid PTSD and Substance Dependence", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "PTSD" ], "interventions": [ { "name": "Paroxetine CR", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Medical University of South Carolina", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 25, "start_date": "2003-01", "completion_date": "2005-05", "has_results": false, "last_update_posted_date": "2007-10-03", "last_synced_at": "2026-09-09T21:25:22.395Z", "location_count": 1, "location_summary": "Charleston, South Carolina", "locations": [ { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00330239" }, { "nct_id": "NCT00429169", "title": "Paroxetine/Bupropion in Suicide Attempters/Ideators With Major Depression", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Depression" ], "interventions": [ { "name": "Paroxetine", "type": "DRUG" }, { "name": "Bupropion", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "New York State Psychiatric Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 101, "start_date": "2004-06", "completion_date": "2013-01", "has_results": true, "last_update_posted_date": "2018-10-30", "last_synced_at": "2026-09-09T21:25:22.395Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00429169" }, { "nct_id": "NCT00610909", "title": "Paroxetine - Controlled Release in the Treatment of Irritable Bowel Syndrome (IBS)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Irritable Bowel Syndrome" ], "interventions": [ { "name": "Paroxetine CR", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 60, "start_date": "2002-01", "completion_date": "2002-12", "has_results": false, "last_update_posted_date": "2013-06-20", "last_synced_at": "2026-09-09T21:25:22.395Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00610909" }, { "nct_id": "NCT00836069", "title": "Fixed Dose Study of PD 0332334 and Paroxetine for the Treatment of Generalized Anxiety Disorder", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Anxiety Disorders" ], "interventions": [ { "name": "No drug name provided by Sponsor; drug referenced as PD 0332334", "type": "DRUG" }, { "name": "Paroxetine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Cedars-Sinai Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 5, "start_date": "2008-10", "completion_date": "2010-04", "has_results": false, "last_update_posted_date": "2019-08-21", "last_synced_at": "2026-09-09T21:25:22.395Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00836069" }, { "nct_id": "NCT00121888", "title": "Trial of Paroxetine-CR for the Treatment of Patients With Post Traumatic Stress Disorder Remaining Symptomatic After Initial Exposure Therapy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Stress Disorders, Post-Traumatic" ], "interventions": [ { "name": "Prolonged Exposure Therapy", "type": "BEHAVIORAL" }, { "name": "Paroxetine-CR", "type": "DRUG" } ], "intervention_types": [ "BEHAVIORAL", "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "72 Years", "sex": "ALL", "summary": "18 Years to 72 Years" }, "enrollment_count": 60, "start_date": "2002-12", "completion_date": "2007-06", "has_results": false, "last_update_posted_date": "2014-06-06", "last_synced_at": "2026-09-09T21:25:22.395Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00121888" }, { "nct_id": "NCT01748955", "title": "Paroxetine/Bupropion in Depression With Suicide Attempt or Thoughts: fMRI Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Depression", "Suicidal Ideation" ], "interventions": [ { "name": "Paroxetine CR for Major Depressive Episode", "type": "DRUG" }, { "name": "Bupropion XL for Major Depressive Episode", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "New York State Psychiatric Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 15, "start_date": "2010-06", "completion_date": "2015-03", "has_results": true, "last_update_posted_date": "2017-11-21", "last_synced_at": "2026-09-09T21:25:22.395Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01748955" }, { "nct_id": "NCT00113295", "title": "Combination of Paroxetine CR and Quetiapine for the Treatment of Refractory Generalized Anxiety Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Anxiety Disorder" ], "interventions": [ { "name": "Continued Paroxetine CR", "type": "DRUG" }, { "name": "Quetiapine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "72 Years", "sex": "ALL", "summary": "18 Years to 72 Years" }, "enrollment_count": 50, "start_date": "2004-02", "completion_date": "2007-11", "has_results": true, "last_update_posted_date": "2014-04-23", "last_synced_at": "2026-09-09T21:25:22.395Z", "location_count": 2, "location_summary": "Boston, Massachusetts • Durham, North Carolina", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00113295" } ] }