{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Phentermine%2FTopiramate+%28Qsymia%29&page=2", "query": { "intervention": "Phentermine/Topiramate (Qsymia)", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 39, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Phentermine%2FTopiramate+%28Qsymia%29&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Phentermine%2FTopiramate+%28Qsymia%29&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-10T05:16:01.295Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04298203", "title": "Role of Pharmacotherapy in Counteracting Weight Regain in Adolescents With Severe Obesity", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Obesity" ], "interventions": [ { "name": "Phentermine-Topiramate", "type": "DRUG" }, { "name": "Meal Replacement Therapy", "type": "DIETARY_SUPPLEMENT" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "DIETARY_SUPPLEMENT", "OTHER" ], "sponsor": "University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "18 Years", "sex": "ALL", "summary": "12 Years to 18 Years" }, "enrollment_count": 100, "start_date": "2021-08-04", "completion_date": "2026-05-22", "has_results": false, "last_update_posted_date": "2026-05-26", "last_synced_at": "2026-10-10T05:16:01.295Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT04298203" }, { "nct_id": "NCT04095104", "title": "Adjunct Phentermine + Topiramate After Bariatric Surgery in 12-24 Year Olds", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Obesity, Morbid", "Bariatric Surgery", "Adolescent", "Young Adult", "Drug Therapy" ], "interventions": [ { "name": "Phentermine", "type": "DRUG" }, { "name": "Immediate Release Topiramate", "type": "DRUG" }, { "name": "Placebo for Phentermine", "type": "DRUG" }, { "name": "Placebo for Immediate Release Topiramate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "24 Years", "sex": "ALL", "summary": "12 Years to 24 Years" }, "enrollment_count": 13, "start_date": "2020-01-15", "completion_date": "2022-01-25", "has_results": true, "last_update_posted_date": "2025-05-23", "last_synced_at": "2026-10-10T05:16:01.295Z", "location_count": 1, "location_summary": "Aurora, Colorado", "locations": [ { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT04095104" }, { "nct_id": "NCT01950520", "title": "Study of Human Non-Shivering Thermogenesis and Basal Metabolic Rate", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Healthy Volunteers" ], "interventions": [ { "name": "Propranolol", "type": "DRUG" }, { "name": "Pindolol", "type": "DRUG" }, { "name": "Dantrolene", "type": "DRUG" }, { "name": "Magnesium Sulfate", "type": "DRUG" }, { "name": "Caffeine", "type": "DRUG" }, { "name": "Qsymia", "type": "DRUG" }, { "name": "Topiramate", "type": "DRUG" }, { "name": "Phentermine", "type": "BEHAVIORAL" }, { "name": "Naltrexone", "type": "DRUG" }, { "name": "Mirabegron 50mg", "type": "DRUG" }, { "name": "Mirabegron 200mg", "type": "DRUG" }, { "name": "Placebo Cohort 1", "type": "DRUG" }, { "name": "Placebo Cohort 2", "type": "DRUG" }, { "name": "Placebo for Mirabegron", "type": "DRUG" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "35 Years", "sex": "MALE", "summary": "18 Years to 35 Years · Male only" }, "enrollment_count": 47, "start_date": "2014-02-07", "completion_date": "2024-06-11", "has_results": true, "last_update_posted_date": "2024-10-16", "last_synced_at": "2026-10-10T05:16:01.295Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT01950520" }, { "nct_id": "NCT05756764", "title": "Anti-obesity Pharmacotherapy and Inflammation", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Obesity" ], "interventions": [ { "name": "Semaglutide", "type": "DRUG" }, { "name": "Phentermine-Topiramate combination", "type": "DRUG" }, { "name": "Phentermine", "type": "DRUG" }, { "name": "Tirzepatide", "type": "DRUG" }, { "name": "Topiramate", "type": "DRUG" }, { "name": "Diethylpropion", "type": "DRUG" }, { "name": "Naltrexone/Bupropion", "type": "DRUG" }, { "name": "Liraglutide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Louisiana State University Health Sciences Center in New Orleans", "sponsor_class": "OTHER", "healthy_volunteers": null, "eligibility": { "minimum_age": "35 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "35 Years to 60 Years" }, "enrollment_count": 30, "start_date": "2023-06-01", "completion_date": "2026-02-20", "has_results": false, "last_update_posted_date": "2025-09-09", "last_synced_at": "2026-10-10T05:16:01.295Z", "location_count": 2, "location_summary": "New Orleans, Louisiana", "locations": [ { "city": "New Orleans", "state": "Louisiana" }, { "city": "New Orleans", "state": "Louisiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT05756764" }, { "nct_id": "NCT00600067", "title": "A VI-0521 Study to Evaluate the Long-term Safety and Efficacy in Type 2 Diabetic Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Diabetes" ], "interventions": [ { "name": "Phentermine/Topiramate", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "VIVUS LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 130, "start_date": "2008-01", "completion_date": "2008-11", "has_results": true, "last_update_posted_date": "2012-09-10", "last_synced_at": "2026-10-10T05:16:01.295Z", "location_count": 9, "location_summary": "Birmingham, Alabama • Los Angeles, California • San Francisco, California + 6 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Spring Valley", "state": "California" }, { "city": "Walnut Creek", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00600067" }, { "nct_id": "NCT04881799", "title": "Phentermine/Topiramate in Adolescents With Type 2 Diabetes and Obesity", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Pediatric Obesity" ], "interventions": [ { "name": "Phentermine/Topiramate (Qsymia)", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "20 Years", "sex": "ALL", "summary": "12 Years to 20 Years" }, "enrollment_count": 13, "start_date": "2022-07-07", "completion_date": "2026-10-27", "has_results": true, "last_update_posted_date": "2026-05-22", "last_synced_at": "2026-10-10T05:16:01.295Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT04881799" }, { "nct_id": "NCT04007393", "title": "SMART Use of Medication for the Treatment of Adolescent Severe Obesity", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Adolescent Obesity" ], "interventions": [ { "name": "Lifestyle Modification Therapy (LSMT)", "type": "BEHAVIORAL" }, { "name": "Phentermine Pill", "type": "DRUG" }, { "name": "Topiramate Pill", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "BEHAVIORAL", "DRUG" ], "sponsor": "University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "12 Years to 17 Years" }, "enrollment_count": 150, "start_date": "2019-11-21", "completion_date": "2025-03-11", "has_results": true, "last_update_posted_date": "2026-05-05", "last_synced_at": "2026-10-10T05:16:01.295Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT04007393" }, { "nct_id": "NCT05215418", "title": "A Study of VI-0521 on Ambulatory Blood Pressure (ABPM) in Overweight or Obese Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Blood Pressure" ], "interventions": [ { "name": "VI-0521", "type": "DRUG" }, { "name": "Phentermine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "VIVUS LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 565, "start_date": "2022-01-25", "completion_date": "2023-04-17", "has_results": true, "last_update_posted_date": "2024-07-17", "last_synced_at": "2026-10-10T05:16:01.295Z", "location_count": 28, "location_summary": "Anniston, Alabama • Mobile, Alabama • Lincoln, California + 25 more", "locations": [ { "city": "Anniston", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Lincoln", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "Sacramento", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05215418" }, { "nct_id": "NCT07188545", "title": "Using Secondary Data to Evaluate Sex-based Heterogeneity of GLP-1 Agonists and SGLT2 Inhibitors on Cardiovascular-Kidney-Metabolic Health (CKMH) Outcomes in Real-world Settings (DASH-CKMH)", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Cardiovascular Kidney Metabolic Syndrome" ], "interventions": [ { "name": "Intervention", "type": "DRUG" }, { "name": "Active Comparator", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Ohio State University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 23280000, "start_date": "2025-09-15", "completion_date": "2029-06-30", "has_results": false, "last_update_posted_date": "2025-09-23", "last_synced_at": "2026-10-10T05:16:01.295Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT07188545" }, { "nct_id": "NCT00842400", "title": "A Drug Interaction Study of VI-0521 With Metformin, Sitagliptan and Probenecid in Healthy Subjects.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Obesity" ], "interventions": [ { "name": "Metformin, VI-0521, Sitagliptan, Probenecid", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "VIVUS LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "19 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "19 Years to 45 Years" }, "enrollment_count": 20, "start_date": "2009-02", "completion_date": "2009-04", "has_results": false, "last_update_posted_date": "2010-01-21", "last_synced_at": "2026-10-10T05:16:01.295Z", "location_count": 1, "location_summary": "Phoenix, Arizona", "locations": [ { "city": "Phoenix", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00842400" } ] }