{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Physical+Fatigue",
    "query": {
      "intervention": "Physical Fatigue"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 369,
    "total_pages": 37,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Physical+Fatigue&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-04T10:28:07.347Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04926350",
      "title": "Resistance Exercise Breaks Improve Ratings of Discomfort and Fatigue in College Students (REX)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sedentary Behavior",
        "Fatigue",
        "Sleepiness",
        "Pain"
      ],
      "interventions": [
        {
          "name": "Resistance Exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Texas A&M University Kingsville",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 24,
      "start_date": "2018-04-09",
      "completion_date": "2019-04-29",
      "has_results": false,
      "last_update_posted_date": "2021-06-15",
      "last_synced_at": "2026-09-04T10:28:07.347Z",
      "location_count": 1,
      "location_summary": "Kingsville, Texas",
      "locations": [
        {
          "city": "Kingsville",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04926350"
    },
    {
      "nct_id": "NCT05397626",
      "title": "Biofeedback and Hydrogen Water as Treatments for Chronic Fatigue Syndrome",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Chronic Fatigue Syndrome"
      ],
      "interventions": [
        {
          "name": "Heart Rhythm Biofeedback",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Hydrogen Water",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Combined treatment: Heart rhythm biofeedback plus hydrogen water",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DIETARY_SUPPLEMENT",
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Stony Brook University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 39,
      "start_date": "2022-05-23",
      "completion_date": "2023-05-23",
      "has_results": false,
      "last_update_posted_date": "2022-05-31",
      "last_synced_at": "2026-09-04T10:28:07.347Z",
      "location_count": 1,
      "location_summary": "Stony Brook, New York",
      "locations": [
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05397626"
    },
    {
      "nct_id": "NCT00509626",
      "title": "Physical Activity or Usual Care in Preventing Weight Gain in Women With Stage I or Stage II Breast Cancer Undergoing Chemotherapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Breast Cancer",
        "Depression",
        "Fatigue",
        "Psychosocial Effects of Cancer and Its Treatment",
        "Weight Changes"
      ],
      "interventions": [
        {
          "name": "exercise intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "questionnaire administration",
          "type": "OTHER"
        },
        {
          "name": "CAM exercise therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "management of therapy complications",
          "type": "PROCEDURE"
        },
        {
          "name": "psychosocial assessment and care",
          "type": "PROCEDURE"
        },
        {
          "name": "quality-of-life assessment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Fox Chase Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 380,
      "start_date": "2007-06",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2010-02-12",
      "last_synced_at": "2026-09-04T10:28:07.347Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00509626"
    },
    {
      "nct_id": "NCT06892496",
      "title": "Patient-reported Outcomes of Donor Site Healing Using Different Palatal Protection Techniques",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mucosal Erosion",
        "Gingival Recession"
      ],
      "interventions": [
        {
          "name": "Visual Analog scale (VAS) questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Vacuum-formed retainer (VFR) technique",
          "type": "OTHER"
        },
        {
          "name": "3-D printed acrylic resin stent (3DS) technique",
          "type": "OTHER"
        },
        {
          "name": "Flowable resin composite stent (FRC) technique",
          "type": "OTHER"
        },
        {
          "name": "Photographs of the patient's palate",
          "type": "OTHER"
        },
        {
          "name": "Measuring graft dimensions",
          "type": "OTHER"
        },
        {
          "name": "Chairside Polymer Stent",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 56,
      "start_date": "2025-03-07",
      "completion_date": "2027-01",
      "has_results": false,
      "last_update_posted_date": "2026-08-05",
      "last_synced_at": "2026-09-04T10:28:07.347Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06892496"
    },
    {
      "nct_id": "NCT07716462",
      "title": "Home-Based High-Intensity Interval Training in Systemic Lupus Erythematosus",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Systemic Lupus Erthematosus",
        "Fatigue",
        "Exercise Training"
      ],
      "interventions": [
        {
          "name": "Personalized Home-Based High-Intensity Interval Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2026-10-01",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-07-21",
      "last_synced_at": "2026-09-04T10:28:07.347Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07716462"
    },
    {
      "nct_id": "NCT03772834",
      "title": "Methylphenidate and Exercise in Reducing Cancer-Related Fatigue in Patients With Prostate Cancer",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Prostate Carcinoma"
      ],
      "interventions": [
        {
          "name": "Exercise Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Methylphenidate",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        },
        {
          "name": "Quality-of-Life Assessment",
          "type": "OTHER"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        },
        {
          "name": "Stretching",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 200,
      "start_date": "2019-03-25",
      "completion_date": "2026-11-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-04",
      "last_synced_at": "2026-09-04T10:28:07.347Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03772834"
    },
    {
      "nct_id": "NCT05340881",
      "title": "Systematic Light Exposure in Pediatric Brain Tumor Survivors",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Brain Tumor"
      ],
      "interventions": [
        {
          "name": "Bright Light Exposure",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Dim Light Exposure",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitive Assessment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "10 Years to 18 Years"
      },
      "enrollment_count": 40,
      "start_date": "2022-10-14",
      "completion_date": "2026-07",
      "has_results": false,
      "last_update_posted_date": "2025-09-18",
      "last_synced_at": "2026-09-04T10:28:07.347Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05340881"
    },
    {
      "nct_id": "NCT04468919",
      "title": "Optimizing BCI-FIT: Brain Computer Interface - Functional Implementation Toolkit",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amyotrophic Lateral Sclerosis",
        "Brainstem Stroke",
        "Muscular Dystrophies",
        "Parkinson's Disease and Parkinsonism",
        "Multiple System Atrophy",
        "Brain Tumor Adult",
        "Spinal Cord Injuries",
        "Locked-in Syndrome"
      ],
      "interventions": [
        {
          "name": "BCI-FIT multi-modal access",
          "type": "BEHAVIORAL"
        },
        {
          "name": "BCI-FIT adaptive signal modeling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "BCI-FIT active querying",
          "type": "BEHAVIORAL"
        },
        {
          "name": "BCI-FIT language modeling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 55,
      "start_date": "2022-07-15",
      "completion_date": "2025-05-05",
      "has_results": false,
      "last_update_posted_date": "2025-05-16",
      "last_synced_at": "2026-09-04T10:28:07.347Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04468919"
    },
    {
      "nct_id": "NCT00499759",
      "title": "Individualized Exercise Programs for Patients Receiving Chemotherapy for Newly Diagnosed Acute or Relapsed Myeloid Leukemia or Lymphoblastic Leukemia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression",
        "Fatigue",
        "Leukemia",
        "Musculoskeletal Complications",
        "Psychosocial Effects of Cancer and Its Treatment"
      ],
      "interventions": [
        {
          "name": "Resting vitals",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Body Composition",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Timed Get-up and Go test (TGUG).",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cardiorespiratory assessment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Handgrip evaluation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Dynamic muscular endurance",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "UNC Lineberger Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 10,
      "start_date": "2006-02",
      "completion_date": "2009-08",
      "has_results": false,
      "last_update_posted_date": "2012-03-06",
      "last_synced_at": "2026-09-04T10:28:07.347Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00499759"
    },
    {
      "nct_id": "NCT05073848",
      "title": "Relationships Between Physical Activity and Different Measures of Fatigue in Cancer Survivors",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cancer Remission"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2021-10-20",
      "completion_date": "2028-06-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-08",
      "last_synced_at": "2026-09-04T10:28:07.347Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05073848"
    }
  ]
}