{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo%3B+placebo+comparator+condition&page=52", "query": { "intervention": "Placebo; placebo comparator condition", "page": 52 }, "page_size": 10 }, "pagination": { "page": 52, "page_size": 10, "total_count": 7773, "total_pages": 778, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo%3B+placebo+comparator+condition&page=53&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo%3B+placebo+comparator+condition&page=51&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-17T10:42:38.628Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00467402", "title": "Efficacy, Safety and Tolerability of Agomelatine in the Prevention of Relapse of Major Depressive Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "agomelatine", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 644, "start_date": "2007-04", "completion_date": null, "has_results": false, "last_update_posted_date": "2020-12-23", "last_synced_at": "2026-10-17T10:42:38.628Z", "location_count": 78, "location_summary": "Birmingham, Alabama • Peoria, Arizona • Tucson, Arizona + 64 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Peoria", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Costa Mesa", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00467402" }, { "nct_id": "NCT05020730", "title": "Trial to Determine the Immunomodulatory Activity of PTM-001 in Patients With Hidradenitis Suppurativa", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hidradenitis Suppurativa" ], "interventions": [ { "name": "PTM-001", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Phoenicis Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 50, "start_date": "2022-05-05", "completion_date": "2024-06", "has_results": false, "last_update_posted_date": "2022-10-26", "last_synced_at": "2026-10-17T10:42:38.628Z", "location_count": 3, "location_summary": "Redwood City, California • Worcester, Massachusetts • Cincinnati, Ohio", "locations": [ { "city": "Redwood City", "state": "California" }, { "city": "Worcester", "state": "Massachusetts" }, { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT05020730" }, { "nct_id": "NCT06682767", "title": "A Nutritional and Pharmacological Intervention for Body, Brain, and Longevity Effects (NIBBLE)", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Cerebral Blood Flow", "APOE 4" ], "interventions": [ { "name": "FMD1 (LNT22-017-1)", "type": "DIETARY_SUPPLEMENT" }, { "name": "Rapamycin", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DIETARY_SUPPLEMENT", "DRUG" ], "sponsor": "Cedars-Sinai Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "45 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "45 Years to 65 Years" }, "enrollment_count": 60, "start_date": "2026-11", "completion_date": "2028-06", "has_results": false, "last_update_posted_date": "2026-09-16", "last_synced_at": "2026-10-17T10:42:38.628Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06682767" }, { "nct_id": "NCT03721900", "title": "Ketamine for Major Depressive Disorder", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "SHX-001 Active low dose", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "SHX-001 Active High dose", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Shenox Pharmaceuticals, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 14, "start_date": "2018-12-28", "completion_date": "2019-06-06", "has_results": false, "last_update_posted_date": "2019-04-25", "last_synced_at": "2026-10-17T10:42:38.628Z", "location_count": 3, "location_summary": "Gaithersburg, Maryland • Boston, Massachusetts • Dayton, Ohio", "locations": [ { "city": "Gaithersburg", "state": "Maryland" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Dayton", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT03721900" }, { "nct_id": "NCT05419011", "title": "Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Colorectal Carcinoma", "Colorectal Neoplasm", "Lynch Syndrome" ], "interventions": [ { "name": "Adenovirus 5 CEA/MUC1/Brachyury Vaccine Tri-Ad5", "type": "BIOLOGICAL" }, { "name": "Biopsy Procedure", "type": "PROCEDURE" }, { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "Colonoscopy", "type": "PROCEDURE" }, { "name": "Nogapendekin Alfa", "type": "DRUG" }, { "name": "Placebo Administration", "type": "DRUG" }, { "name": "Questionnaire Administration", "type": "OTHER" } ], "intervention_types": [ "BIOLOGICAL", "PROCEDURE", "DRUG", "OTHER" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 186, "start_date": "2023-05-08", "completion_date": "2028-01-01", "has_results": false, "last_update_posted_date": "2026-06-17", "last_synced_at": "2026-10-17T10:42:38.628Z", "location_count": 13, "location_summary": "Phoenix, Arizona • Tucson, Arizona • San Francisco, California + 10 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "San Francisco", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT05419011" }, { "nct_id": "NCT00033371", "title": "Celecoxib With or Without Eflornithine in Preventing Colorectal Cancer in Patients With Familial Adenomatous Polyposis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Colorectal Cancer", "Familial Adenomatous Polyposis" ], "interventions": [ { "name": "Celecoxib", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" }, { "name": "eflornithine", "type": "DRUG" }, { "name": "Laboratory biomarker analysis", "type": "OTHER" }, { "name": "Questionnaire administration", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 205, "start_date": "2001-12-13", "completion_date": "2009-03-24", "has_results": true, "last_update_posted_date": "2020-09-29", "last_synced_at": "2026-10-17T10:42:38.628Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00033371" }, { "nct_id": "NCT03007394", "title": "Lorcaserin in the Treatment of Cocaine Use Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Cocaine-Related Disorders" ], "interventions": [ { "name": "Lorcaserin", "type": "DRUG" }, { "name": "Placebo Oral Capsule", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute on Drug Abuse (NIDA)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 272, "start_date": "2017-12-19", "completion_date": "2019-12-01", "has_results": true, "last_update_posted_date": "2020-08-05", "last_synced_at": "2026-10-17T10:42:38.628Z", "location_count": 12, "location_summary": "La Jolla, California • Los Angeles, California • Newport Beach, California + 9 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Newport Beach", "state": "California" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Lakeland", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03007394" }, { "nct_id": "NCT05379153", "title": "Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Vaginal Atrophy", "Breast Carcinoma" ], "interventions": [ { "name": "Laser Therapy", "type": "DEVICE" }, { "name": "Sham Intervention", "type": "DEVICE" }, { "name": "Questionnaire Administration", "type": "OTHER" }, { "name": "Quality of Life Assessment", "type": "OTHER" } ], "intervention_types": [ "DEVICE", "OTHER" ], "sponsor": "Alliance for Clinical Trials in Oncology", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "22 Years", "maximum_age": null, "sex": "FEMALE", "summary": "22 Years and older · Female only" }, "enrollment_count": 250, "start_date": "2026-04-21", "completion_date": "2027-05", "has_results": false, "last_update_posted_date": "2026-09-03", "last_synced_at": "2026-10-17T10:42:38.628Z", "location_count": 2, "location_summary": "Ann Arbor, Michigan • Columbus, Ohio", "locations": [ { "city": "Ann Arbor", "state": "Michigan" }, { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT05379153" }, { "nct_id": "NCT00407212", "title": "A Study of Three Doses of TCH346 in Patients With Early Parkinson's Disease to Evaluate Safety and Efficacy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Parkinson's Disease" ], "interventions": [ { "name": "TCH346 (dibenz[b,f]oxepin-10-ylmethyl-prop-2-ynyl-amine, hydrogen maleate salt)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis", "sponsor_class": "INDUSTRY", "healthy_volunteers": null, "eligibility": { "minimum_age": "30 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "30 Years to 80 Years" }, "enrollment_count": 301, "start_date": "2002-01", "completion_date": "2003-11", "has_results": false, "last_update_posted_date": "2011-11-23", "last_synced_at": "2026-10-17T10:42:38.628Z", "location_count": 11, "location_summary": "Phoenix, Arizona • Berkley, California • Fountain Valley, California + 8 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Berkley", "state": "California" }, { "city": "Fountain Valley", "state": "California" }, { "city": "Sunnyvale", "state": "California" }, { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT00407212" }, { "nct_id": "NCT00120328", "title": "To Determine the Effects of Avosentan on Doubling of Serum Creatinine, End Stage Renal Disease and Death in Diabetic Nephropathy", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Diabetic Nephropathy" ], "interventions": [ { "name": "SPP301", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Speedel Pharma Ltd.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "21 Years to 80 Years" }, "enrollment_count": 2364, "start_date": "2005-07", "completion_date": "2007-02", "has_results": false, "last_update_posted_date": "2007-10-05", "last_synced_at": "2026-10-17T10:42:38.628Z", "location_count": 1, "location_summary": "Greenville, North Carolina", "locations": [ { "city": "Greenville", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00120328" } ] }