{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+%28for+nortriptyline%29",
    "query": {
      "intervention": "Placebo (for nortriptyline)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-04T12:36:24.354Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04226365",
      "title": "Pediatric Concussion Outcomes",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Concussion Post Syndrome",
        "Headaches Posttraumatic",
        "Mild Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "Nortriptyline",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Lancaster General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "13 Years to 21 Years"
      },
      "enrollment_count": 8,
      "start_date": "2020-02-15",
      "completion_date": "2023-05-31",
      "has_results": true,
      "last_update_posted_date": "2025-09-10",
      "last_synced_at": "2026-10-04T12:36:24.354Z",
      "location_count": 1,
      "location_summary": "Lancaster, Pennsylvania",
      "locations": [
        {
          "city": "Lancaster",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04226365"
    },
    {
      "nct_id": "NCT00018148",
      "title": "Combined Nortriptyline and Transdermal Nicotine for Smoking Cessation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Smoking"
      ],
      "interventions": [
        {
          "name": "nortriptyline",
          "type": "DRUG"
        },
        {
          "name": "transdermal nicotine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 158,
      "start_date": "1998-04",
      "completion_date": "2003-01",
      "has_results": false,
      "last_update_posted_date": "2010-09-15",
      "last_synced_at": "2026-10-04T12:36:24.354Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00018148"
    },
    {
      "nct_id": "NCT04404439",
      "title": "Treatment of Tinnitus With Migraine Medications",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Tinnitus, Subjective",
        "Tinnitus"
      ],
      "interventions": [
        {
          "name": "Nortriptyline + Topiramate",
          "type": "DRUG"
        },
        {
          "name": "Verapamil + Paroxetine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "25 Years to 85 Years"
      },
      "enrollment_count": 78,
      "start_date": "2019-09-26",
      "completion_date": "2023-12-30",
      "has_results": true,
      "last_update_posted_date": "2026-04-16",
      "last_synced_at": "2026-10-04T12:36:24.354Z",
      "location_count": 1,
      "location_summary": "Orange, California",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04404439"
    },
    {
      "nct_id": "NCT03844412",
      "title": "Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Vestibulodynia",
        "Temporomandibular Disorder",
        "Fibromyalgia Syndrome",
        "Irritable Bowel Syndrome",
        "Migraines",
        "Tension Headache",
        "Endometriosis",
        "Interstitial Cystitis",
        "Back Pain",
        "Chronic Fatigue Syndrome"
      ],
      "interventions": [
        {
          "name": "5% lidocaine/5 mg/ml 0.02% estradiol compound cream",
          "type": "DRUG"
        },
        {
          "name": "Nortriptyline",
          "type": "DRUG"
        },
        {
          "name": "Placebo cream",
          "type": "DRUG"
        },
        {
          "name": "Placebo pill",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 209,
      "start_date": "2019-11-04",
      "completion_date": "2024-05-30",
      "has_results": true,
      "last_update_posted_date": "2026-03-19",
      "last_synced_at": "2026-10-04T12:36:24.354Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California • Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03844412"
    },
    {
      "nct_id": "NCT05582837",
      "title": "Treatment of Meniere's Disease With Migraine Medications",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Ménière"
      ],
      "interventions": [
        {
          "name": "nortriptyline + topiramate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "25 Years to 85 Years"
      },
      "enrollment_count": 40,
      "start_date": "2022-08-01",
      "completion_date": "2027-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-22",
      "last_synced_at": "2026-10-04T12:36:24.354Z",
      "location_count": 1,
      "location_summary": "Orange, California",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05582837"
    },
    {
      "nct_id": "NCT07498140",
      "title": "Procedural Framing and Epidural Steroid Injection Outcomes",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lumbosacral Radiculopathy"
      ],
      "interventions": [
        {
          "name": "Behavioral manipulation of ESI expectations",
          "type": "BEHAVIORAL"
        },
        {
          "name": "No behavioral manipulation of ESI expectations",
          "type": "OTHER"
        },
        {
          "name": "No behavioral manipulation of pharmacotherapy expectations",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 210,
      "start_date": "2026-03-30",
      "completion_date": "2028-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-18",
      "last_synced_at": "2026-10-04T12:36:24.354Z",
      "location_count": 2,
      "location_summary": "Chicago, Illinois • Bethesda, Maryland",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07498140"
    },
    {
      "nct_id": "NCT00539240",
      "title": "Role of Pain Modulation in GERD Patients Who Failed Standard Dose PPI",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Gastroesophageal Reflux Disease"
      ],
      "interventions": [
        {
          "name": "Rabeprazole 20mg, placebo dinner and bedtime",
          "type": "DRUG"
        },
        {
          "name": "Rabeprazole 20 mg two times, Placebo at bedtime",
          "type": "DRUG"
        },
        {
          "name": "Rabeprazole 20mg,placebo dinner ,Low dose Tricyclic Antidepressant",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 236,
      "start_date": "2006-04",
      "completion_date": "2011-11",
      "has_results": true,
      "last_update_posted_date": "2014-08-18",
      "last_synced_at": "2026-10-04T12:36:24.354Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00539240"
    },
    {
      "nct_id": "NCT00765895",
      "title": "Nortriptyline for Idiopathic Gastroparesis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Idiopathic Gastroparesis"
      ],
      "interventions": [
        {
          "name": "Nortriptyline Hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "Placebo (for nortriptyline)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 130,
      "start_date": "2009-01",
      "completion_date": "2012-10",
      "has_results": true,
      "last_update_posted_date": "2020-05-14",
      "last_synced_at": "2026-10-04T12:36:24.354Z",
      "location_count": 7,
      "location_summary": "San Francisco, California • Stanford, California • Ann Arbor, Michigan + 4 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Jackson",
          "state": "Mississippi"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00765895"
    },
    {
      "nct_id": "NCT00045916",
      "title": "Optimizing Electroconvulsive Therapy for Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Depression",
        "Depressive Disorder",
        "Bipolar Disorder"
      ],
      "interventions": [
        {
          "name": "High dosage electroconvulsive therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Nortriptyline",
          "type": "DRUG"
        },
        {
          "name": "Venlafaxine",
          "type": "DRUG"
        },
        {
          "name": "Lithium",
          "type": "DRUG"
        },
        {
          "name": "Low dosage electroconvulsive therapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "New York State Psychiatric Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 340,
      "start_date": "2001-02",
      "completion_date": "2006-12",
      "has_results": false,
      "last_update_posted_date": "2013-08-13",
      "last_synced_at": "2026-10-04T12:36:24.354Z",
      "location_count": 4,
      "location_summary": "St Louis, Missouri • New York, New York • Winston-Salem, North Carolina + 1 more",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00045916"
    },
    {
      "nct_id": "NCT00547703",
      "title": "Effect of Nortriptyline on Abdominal Pain/Discomfort and Quality of Life in Patients With Nonulcer Dyspepsia",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Non Ulcer Dyspepsia"
      ],
      "interventions": [
        {
          "name": "Nortriptyline",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 5,
      "start_date": "2008-02",
      "completion_date": "2010-06",
      "has_results": true,
      "last_update_posted_date": "2026-08-25",
      "last_synced_at": "2026-10-04T12:36:24.354Z",
      "location_count": 1,
      "location_summary": "Weston, Florida",
      "locations": [
        {
          "city": "Weston",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00547703"
    }
  ]
}