{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+%2B+Cocaine&page=2", "query": { "intervention": "Placebo + Cocaine", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 228, "total_pages": 23, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+%2B+Cocaine&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+%2B+Cocaine&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-04T13:37:12.677Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05610072", "title": "Behavioral Effects of Drugs (Inpatient): 43 (Opioids, Cocaine, n-Acetylcysteine)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Cocaine Use Disorder", "Opioid Use Disorder", "Stimulant Use Disorder" ], "interventions": [ { "name": "n-acetylcysteine", "type": "DRUG" }, { "name": "Hydromorphone", "type": "DRUG" }, { "name": "Placebo n-acetylcystine", "type": "DRUG" }, { "name": "Placebo hydromorphone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "William Stoops", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 12, "start_date": "2022-12-15", "completion_date": "2026-03-27", "has_results": false, "last_update_posted_date": "2026-05-05", "last_synced_at": "2026-10-04T13:37:12.677Z", "location_count": 2, "location_summary": "Lexington, Kentucky", "locations": [ { "city": "Lexington", "state": "Kentucky" }, { "city": "Lexington", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT05610072" }, { "nct_id": "NCT01746940", "title": "Topical Application of Cocaine HCl 4% and 10% on Safety and Efficacy in Local (Topical) Anesthesia", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Diagnostic", "Procedures and Surgeries on or Through Accessible Mucous Membranes", "of the Nasal Cavities" ], "interventions": [ { "name": "Cocaine HCl 4% Topical Solution", "type": "DRUG" }, { "name": "Cocaine HCl 10% Topical Solution", "type": "DRUG" }, { "name": "Placebo Topical Solution", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Lannett Company, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 159, "start_date": "2014-03", "completion_date": "2015-07", "has_results": true, "last_update_posted_date": "2017-05-12", "last_synced_at": "2026-10-04T13:37:12.677Z", "location_count": 2, "location_summary": "Bridgeport, Connecticut • Plano, Texas", "locations": [ { "city": "Bridgeport", "state": "Connecticut" }, { "city": "Plano", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01746940" }, { "nct_id": "NCT05841979", "title": "The Lived Experiences Measured Using Rings Pilot Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Depression", "Stress", "Sleep", "Anxiety" ], "interventions": [ { "name": "Moodlifters", "type": "BEHAVIORAL" }, { "name": "Physical Activity", "type": "BEHAVIORAL" }, { "name": "Nature Experiences", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Vermont", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "25 Years", "sex": "ALL", "summary": "18 Years to 25 Years" }, "enrollment_count": 188, "start_date": "2022-12-01", "completion_date": "2024-06-01", "has_results": false, "last_update_posted_date": "2025-04-17", "last_synced_at": "2026-10-04T13:37:12.677Z", "location_count": 1, "location_summary": "Burlington, Vermont", "locations": [ { "city": "Burlington", "state": "Vermont" } ], "official_url": "https://clinicaltrials.gov/study/NCT05841979" }, { "nct_id": "NCT03519022", "title": "Behavioral Effects of Drugs: Inpatient (35)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Cocaine Use Disorder" ], "interventions": [ { "name": "Cocaine", "type": "DRUG" }, { "name": "Placebo oral capsule", "type": "DRUG" }, { "name": "Methylphenidate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Craig Rush", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 9, "start_date": "2018-06-01", "completion_date": "2019-05-31", "has_results": false, "last_update_posted_date": "2019-06-25", "last_synced_at": "2026-10-04T13:37:12.677Z", "location_count": 1, "location_summary": "Lexington, Kentucky", "locations": [ { "city": "Lexington", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT03519022" }, { "nct_id": "NCT03937986", "title": "Suvorexant and Cocaine", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Cocaine Use Disorder" ], "interventions": [ { "name": "Suvorexant", "type": "DRUG" }, { "name": "Cocaine", "type": "DRUG" }, { "name": "Placebo oral capsule", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "William Stoops", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 8, "start_date": "2019-07-11", "completion_date": "2022-04-30", "has_results": true, "last_update_posted_date": "2023-02-09", "last_synced_at": "2026-10-04T13:37:12.677Z", "location_count": 1, "location_summary": "Lexington, Kentucky", "locations": [ { "city": "Lexington", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT03937986" }, { "nct_id": "NCT01535573", "title": "Citalopram for Cocaine Dependence", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Cocaine Dependence" ], "interventions": [ { "name": "Citalopram", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Joy Schmitz", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 108, "start_date": "2010-12", "completion_date": "2016-07", "has_results": true, "last_update_posted_date": "2020-09-16", "last_synced_at": "2026-10-04T13:37:12.677Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01535573" }, { "nct_id": "NCT04907357", "title": "rTMS for Stimulant Use Disorders", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cocaine Use Disorder", "Methamphetamine Abuse", "Cocaine Dependence", "Methamphetamine Dependence", "Stimulant Use", "Stimulant Abuse", "Methamphetamine Use Disorder", "Cocaine Abuse", "Stimulant Use Disorder" ], "interventions": [ { "name": "rTMS", "type": "DEVICE" }, { "name": "Sham (Placebo)", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Medical University of South Carolina", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 129, "start_date": "2022-02-04", "completion_date": "2024-06-07", "has_results": true, "last_update_posted_date": "2025-07-03", "last_synced_at": "2026-10-04T13:37:12.677Z", "location_count": 4, "location_summary": "Winston-Salem, North Carolina • Charleston, South Carolina • Dallas, Texas + 1 more", "locations": [ { "city": "Winston-Salem", "state": "North Carolina" }, { "city": "Charleston", "state": "South Carolina" }, { "city": "Dallas", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04907357" }, { "nct_id": "NCT05063201", "title": "Cariprazine for Comorbid Cocaine and Opioid Use Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Opioid-use Disorder", "Cocaine Use Disorder" ], "interventions": [ { "name": "Cariprazine 1.5 MG", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Kyle Kampman", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 26, "start_date": "2022-08-05", "completion_date": "2025-12-31", "has_results": false, "last_update_posted_date": "2026-01-23", "last_synced_at": "2026-10-04T13:37:12.677Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT05063201" }, { "nct_id": "NCT03953612", "title": "The Role of Neuroactive Steroids in Stress, Drug Craving and Drug Use in Cocaine Use Disorders", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Cocaine-Related Disorders" ], "interventions": [ { "name": "Pregnenolone (PREG)", "type": "DRUG" }, { "name": "Placebos", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 58, "start_date": "2019-03-12", "completion_date": "2023-05-08", "has_results": true, "last_update_posted_date": "2024-07-03", "last_synced_at": "2026-10-04T13:37:12.677Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT03953612" }, { "nct_id": "NCT00580827", "title": "Clinical Efficacy of Disulfiram in LAAM-Maintained Cocaine Abusers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cocaine-Related Disorder", "Opiate Dependence" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Disulfiram", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 126, "start_date": "2003-09", "completion_date": null, "has_results": false, "last_update_posted_date": "2020-03-31", "last_synced_at": "2026-10-04T13:37:12.677Z", "location_count": 1, "location_summary": "West Haven, Connecticut", "locations": [ { "city": "West Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT00580827" } ] }