{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+Comparator+general+instructions",
    "query": {
      "intervention": "Placebo Comparator general instructions"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+Comparator+general+instructions&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-08T19:53:46.232Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07642869",
      "title": "Multivitamin and Mineral Supplementation and Healthy Aging",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Aging",
        "Multivitamin and Mineral Supplementation"
      ],
      "interventions": [
        {
          "name": "MVM Core Blend",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "MVM Gold Blend",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "40 Years to 60 Years"
      },
      "enrollment_count": 150,
      "start_date": "2025-09-05",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-15",
      "last_synced_at": "2026-09-08T19:53:46.232Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07642869"
    },
    {
      "nct_id": "NCT01625845",
      "title": "Anti-INFLammatory to Address Mood and Endothelial Dysfunction (INFLAMED)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Major Depressive Disorder",
        "Depression",
        "Depressive Symptoms",
        "Cardiovascular Disease (CVD)",
        "Coronary Artery Disease (CAD)",
        "Heart Disease"
      ],
      "interventions": [
        {
          "name": "Pentoxifylline",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        },
        {
          "name": "Standard Treatment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2012-06",
      "completion_date": "2014-05",
      "has_results": true,
      "last_update_posted_date": "2015-12-03",
      "last_synced_at": "2026-09-08T19:53:46.232Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01625845"
    },
    {
      "nct_id": "NCT05123118",
      "title": "Lung and Breast Cancer Prevention by an Integrated Intervention of Maternal Smoking Cessation and Breastfeeding",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking, Cigarette",
        "Breastfeeding"
      ],
      "interventions": [
        {
          "name": "Integrated intervention of smoking cessation and breastfeeding",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Attention placebo control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Xiaozhong Wen",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 40,
      "start_date": "2021-01-01",
      "completion_date": "2023-10-30",
      "has_results": true,
      "last_update_posted_date": "2025-04-17",
      "last_synced_at": "2026-09-08T19:53:46.232Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05123118"
    },
    {
      "nct_id": "NCT06672666",
      "title": "Use of CBD in the Treatment of Anxiety",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Anxiety",
        "Generalized Anxiety Disorder",
        "Sleep Problems"
      ],
      "interventions": [
        {
          "name": "Hemp Derived Cannabidiol Extract",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 30,
      "start_date": "2025-01-06",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-09",
      "last_synced_at": "2026-09-08T19:53:46.232Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06672666"
    },
    {
      "nct_id": "NCT04713657",
      "title": "Beta-blocker Administration for Cardiomyocyte Division",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Tetralogy of Fallot",
        "Double Outlet Right Ventricle"
      ],
      "interventions": [
        {
          "name": "N-thymidine",
          "type": "OTHER"
        },
        {
          "name": "Urine Collection",
          "type": "OTHER"
        },
        {
          "name": "Echocardiogram",
          "type": "PROCEDURE"
        },
        {
          "name": "Cardiac MRI (CMR)",
          "type": "PROCEDURE"
        },
        {
          "name": "Propranolol Hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Physical Exam",
          "type": "PROCEDURE"
        },
        {
          "name": "Specimen Collection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Days",
        "maximum_age": "60 Days",
        "sex": "ALL",
        "summary": "30 Days to 60 Days"
      },
      "enrollment_count": 40,
      "start_date": "2022-12-16",
      "completion_date": "2030-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-11-18",
      "last_synced_at": "2026-09-08T19:53:46.232Z",
      "location_count": 3,
      "location_summary": "New York, New York • Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04713657"
    },
    {
      "nct_id": "NCT02362243",
      "title": "Worksite Exercise Interventions for Low Back Injury Prevention in Firefighters",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Experimental Intervention",
          "type": "OTHER"
        },
        {
          "name": "Placebo Comparator",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of South Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 264,
      "start_date": "2016-03",
      "completion_date": "2018-04-30",
      "has_results": false,
      "last_update_posted_date": "2018-07-02",
      "last_synced_at": "2026-09-08T19:53:46.232Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02362243"
    },
    {
      "nct_id": "NCT02336217",
      "title": "Glycemic Emergency Management (GEM); An App for Rapid Response to Hypoglycemic and Hyperglycemic Situations",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "Experimental Group instructions for glucose management via App",
          "type": "OTHER"
        },
        {
          "name": "Placebo Comparator general instructions",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Marshall University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 40,
      "start_date": "2014-09",
      "completion_date": "2026-06",
      "has_results": false,
      "last_update_posted_date": "2025-05-23",
      "last_synced_at": "2026-09-08T19:53:46.232Z",
      "location_count": 1,
      "location_summary": "Huntington, West Virginia",
      "locations": [
        {
          "city": "Huntington",
          "state": "West Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02336217"
    },
    {
      "nct_id": "NCT05419297",
      "title": "True Functional Restoration and Analgesia in Non-Radicular Low Back Pain",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Back Pain Lower Back Chronic",
        "Chronic Pain"
      ],
      "interventions": [
        {
          "name": "Buprenorphine Buccal Film [Belbuca]",
          "type": "DRUG"
        },
        {
          "name": "Urine Drug Screening",
          "type": "OTHER"
        },
        {
          "name": "actigraph",
          "type": "DEVICE"
        },
        {
          "name": "PROMIS 29",
          "type": "BEHAVIORAL"
        },
        {
          "name": "sit to stand test",
          "type": "OTHER"
        },
        {
          "name": "numerical rating scale pain score",
          "type": "OTHER"
        },
        {
          "name": "patient global impression of function",
          "type": "BEHAVIORAL"
        },
        {
          "name": "PROMIS - sleep",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "Carolinas Pain Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2022-08-03",
      "completion_date": "2023-07",
      "has_results": false,
      "last_update_posted_date": "2023-02-08",
      "last_synced_at": "2026-09-08T19:53:46.232Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05419297"
    },
    {
      "nct_id": "NCT01177137",
      "title": "Tinnitus Retraining Therapy Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Subjective Tinnitus"
      ],
      "interventions": [
        {
          "name": "Conventional sound generator (SG)",
          "type": "DEVICE"
        },
        {
          "name": "Placebo sound generator (placebo SG)",
          "type": "DEVICE"
        },
        {
          "name": "Standard of Care (SC)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Directive Counseling (DC)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "Johns Hopkins Bloomberg School of Public Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 151,
      "start_date": "2011-07",
      "completion_date": "2017-02",
      "has_results": true,
      "last_update_posted_date": "2018-11-21",
      "last_synced_at": "2026-09-08T19:53:46.232Z",
      "location_count": 6,
      "location_summary": "Camp Pendleton, California • San Diego, California • Travis Air Force Base, California + 3 more",
      "locations": [
        {
          "city": "Camp Pendleton",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Travis Air Force Base",
          "state": "California"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Lackland Air Force Base",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01177137"
    },
    {
      "nct_id": "NCT00890526",
      "title": "Intervention for Reduced Sound Tolerance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Hyperacusis"
      ],
      "interventions": [
        {
          "name": "Sound Therapy (Tinnitus Retraining Therapy)",
          "type": "OTHER"
        },
        {
          "name": "Counseling (Tinnitus Retraining Therapy)",
          "type": "OTHER"
        },
        {
          "name": "No Counseling",
          "type": "OTHER"
        },
        {
          "name": "Placebo Sound Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Alabama, Tuscaloosa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 36,
      "start_date": "2002-07",
      "completion_date": "2010-09",
      "has_results": false,
      "last_update_posted_date": "2012-06-21",
      "last_synced_at": "2026-09-08T19:53:46.232Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00890526"
    }
  ]
}