{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+and+zolpidem",
    "query": {
      "intervention": "Placebo and zolpidem"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 47,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+and+zolpidem&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-25T01:46:10.140Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00227942",
      "title": "Estrogen for Treating Depression in Menopausal Women With Hot Flashes and Insomnia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Sleep Initiation and Maintenance Disorders",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Estrogen Replacement Therapy",
          "type": "DRUG"
        },
        {
          "name": "Zolpidem",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Hadine Joffe, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 60 Years · Female only"
      },
      "enrollment_count": 86,
      "start_date": "2003-08",
      "completion_date": "2007-11",
      "has_results": false,
      "last_update_posted_date": "2014-05-26",
      "last_synced_at": "2026-09-25T01:46:10.140Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00227942"
    },
    {
      "nct_id": "NCT05351541",
      "title": "Psilocybin Therapy for Chronic Low Back Pain",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Chronic Low-back Pain"
      ],
      "interventions": [
        {
          "name": "Psilocybin therapy with Zolpidem and Modafinil",
          "type": "DRUG"
        },
        {
          "name": "Psilocybin therapy with Zolpidem",
          "type": "DRUG"
        },
        {
          "name": "Psilocybin therapy with Modafinil",
          "type": "DRUG"
        },
        {
          "name": "Psilocybin therapy with Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Joshua Woolley, MD, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "25 Years to 70 Years"
      },
      "enrollment_count": 30,
      "start_date": "2023-12-01",
      "completion_date": "2026-09",
      "has_results": false,
      "last_update_posted_date": "2026-04-29",
      "last_synced_at": "2026-09-25T01:46:10.140Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05351541"
    },
    {
      "nct_id": "NCT00156533",
      "title": "Long Term Treatment With Zolpidem: Nightly and Intermittent Dosing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Insomnia",
        "Primary Insomnia",
        "Psychophysiologic Insomnia"
      ],
      "interventions": [
        {
          "name": "Zolpidem",
          "type": "DRUG"
        },
        {
          "name": "Sugar Pill",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "25 Years to 55 Years"
      },
      "enrollment_count": 20,
      "start_date": "2005-03",
      "completion_date": "2008-02",
      "has_results": true,
      "last_update_posted_date": "2015-11-20",
      "last_synced_at": "2026-09-25T01:46:10.140Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00156533"
    },
    {
      "nct_id": "NCT05540574",
      "title": "Trial of Zolpidem for Sleep in Children With Autism",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Autism",
        "Autism Spectrum Disorder"
      ],
      "interventions": [
        {
          "name": "Zolpidem",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "8 Years to 17 Years"
      },
      "enrollment_count": 26,
      "start_date": "2023-08-09",
      "completion_date": "2028-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-27",
      "last_synced_at": "2026-09-25T01:46:10.140Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05540574"
    },
    {
      "nct_id": "NCT07542756",
      "title": "A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for Insomnia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Insomnia",
        "Insomnia Disorder",
        "Chronic Insomnia",
        "Chronic Insomnia Disorder"
      ],
      "interventions": [
        {
          "name": "Sleep Hygiene Education",
          "type": "OTHER"
        },
        {
          "name": "Melatonin IR, 3 mg",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Melatonin IR, 5 mg",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Diphenhydramine, 25 mg",
          "type": "DRUG"
        },
        {
          "name": "Diphenhydramine, 50 mg",
          "type": "DRUG"
        },
        {
          "name": "Doxepin, 3 mg",
          "type": "DRUG"
        },
        {
          "name": "Doxepin, 6 mg",
          "type": "DRUG"
        },
        {
          "name": "Trazodone, 50 mg",
          "type": "DRUG"
        },
        {
          "name": "Trazodone, 100 mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Zolpidem, 5 mg",
          "type": "DRUG"
        },
        {
          "name": "Zolpidem, 10 mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIETARY_SUPPLEMENT",
        "DRUG"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 1200,
      "start_date": "2026-05-01",
      "completion_date": "2032-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-09-16",
      "last_synced_at": "2026-09-25T01:46:10.140Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07542756"
    },
    {
      "nct_id": "NCT00716521",
      "title": "Effect Of Treatment With Oral Zolpidem On Polysomnography And Actigraphy Measures In Healthy Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Methodology Study"
      ],
      "interventions": [
        {
          "name": "placebo",
          "type": "DRUG"
        },
        {
          "name": "zolpidem",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 11,
      "start_date": "2008-07",
      "completion_date": "2008-10",
      "has_results": false,
      "last_update_posted_date": "2009-04-24",
      "last_synced_at": "2026-09-25T01:46:10.140Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00716521"
    },
    {
      "nct_id": "NCT00630175",
      "title": "Evaluation of the Hypnotic Properties of Zolpidem-MR 12.5 mg and Zolpidem 10 mg Marketed Product Compared to Placebo in Patients With Primary Insomnia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Sleep Initiation and Maintenance Disorders"
      ],
      "interventions": [
        {
          "name": "zolpidem-MR (modified release)",
          "type": "DRUG"
        },
        {
          "name": "zolpidem (SL800750)",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Sanofi",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 113,
      "start_date": "2003-09",
      "completion_date": "2004-02",
      "has_results": false,
      "last_update_posted_date": "2009-05-18",
      "last_synced_at": "2026-09-25T01:46:10.140Z",
      "location_count": 1,
      "location_summary": "Bridgewater, New Jersey",
      "locations": [
        {
          "city": "Bridgewater",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00630175"
    },
    {
      "nct_id": "NCT00814502",
      "title": "Zolpidem CR and Hospitalized Patients With Dementia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dementia",
        "Alzheimer Disease",
        "Dementia, Vascular",
        "Sleep Disorders",
        "Circadian Dysregulation"
      ],
      "interventions": [
        {
          "name": "Zolpidem CR",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "60 Years to 99 Years"
      },
      "enrollment_count": 20,
      "start_date": "2008-12",
      "completion_date": "2013-12",
      "has_results": true,
      "last_update_posted_date": "2017-05-22",
      "last_synced_at": "2026-09-25T01:46:10.140Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00814502"
    },
    {
      "nct_id": "NCT00893269",
      "title": "The Effect of Marijuana and Prescription Medications in Mood, Performance and Sleep",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Marijuana Dependence"
      ],
      "interventions": [
        {
          "name": "eszopiclone",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "ramelteon",
          "type": "DRUG"
        },
        {
          "name": "zolpidem",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 36,
      "start_date": "2008-10",
      "completion_date": "2010-10",
      "has_results": false,
      "last_update_posted_date": "2013-12-05",
      "last_synced_at": "2026-09-25T01:46:10.140Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00893269"
    },
    {
      "nct_id": "NCT01463098",
      "title": "A 2-Part Single Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2006",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Insomnia"
      ],
      "interventions": [
        {
          "name": "E2006 1.0 mg",
          "type": "DRUG"
        },
        {
          "name": "E2006 2.5 mg",
          "type": "DRUG"
        },
        {
          "name": "E2006 5.0 mg",
          "type": "DRUG"
        },
        {
          "name": "E2006 10.0 mg",
          "type": "DRUG"
        },
        {
          "name": "E2006 25.0 mg",
          "type": "DRUG"
        },
        {
          "name": "E2006 50.0 mg",
          "type": "DRUG"
        },
        {
          "name": "E2006 100 mg",
          "type": "DRUG"
        },
        {
          "name": "E2006 200 mg",
          "type": "DRUG"
        },
        {
          "name": "Zolpidem 10 mg",
          "type": "DRUG"
        },
        {
          "name": "E2006 Matched Placebo or Zolpidem Matched Placebo",
          "type": "DRUG"
        },
        {
          "name": "E2006 Matched Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Eisai Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 122,
      "start_date": "2011-10-05",
      "completion_date": "2012-08-11",
      "has_results": true,
      "last_update_posted_date": "2020-01-18",
      "last_synced_at": "2026-09-25T01:46:10.140Z",
      "location_count": 2,
      "location_summary": "New York, New York • Cincinnati, Ohio",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01463098"
    }
  ]
}