{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+for+Febuxostat", "query": { "intervention": "Placebo for Febuxostat" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 13, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+for+Febuxostat&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-21T16:46:09.789Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03118739", "title": "Intensive Uric Acid Lowering With Verinurad and Febuxostat in Patients With Albuminuria", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hyperuricemia", "Albuminuria", "Type 2 Diabetes" ], "interventions": [ { "name": "Verinurad 9 mg+Febuxostat 80 mg", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AstraZeneca", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 60, "start_date": "2017-05-18", "completion_date": "2018-08-13", "has_results": true, "last_update_posted_date": "2020-01-10", "last_synced_at": "2026-09-21T16:46:09.789Z", "location_count": 18, "location_summary": "Canyon Country, California • Chula Vista, California • Corona, California + 12 more", "locations": [ { "city": "Canyon Country", "state": "California" }, { "city": "Chula Vista", "state": "California" }, { "city": "Corona", "state": "California" }, { "city": "Escondido", "state": "California" }, { "city": "Lakewood", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03118739" }, { "nct_id": "NCT02128490", "title": "Efficacy and Safety of Extended Release and Immediate Release Febuxostat in Participants With Gout and Moderate Renal Impairment", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Gout", "Moderate Renal Impairment" ], "interventions": [ { "name": "Febuxostat IR", "type": "DRUG" }, { "name": "Febuxostat XR", "type": "DRUG" }, { "name": "Febuxostat placebo", "type": "DRUG" }, { "name": "Colchicine", "type": "DRUG" }, { "name": "Naproxen", "type": "DRUG" }, { "name": "Lansoprazole", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 189, "start_date": "2014-05", "completion_date": "2015-10", "has_results": true, "last_update_posted_date": "2016-11-03", "last_synced_at": "2026-09-21T16:46:09.789Z", "location_count": 89, "location_summary": "Birmingham, Alabama • Muscle Shoals, Alabama • Phoenix, Arizona + 75 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Muscle Shoals", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Little Rock", "state": "Arkansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02128490" }, { "nct_id": "NCT01077284", "title": "Febuxostat Versus Allopurinol or Placebo in Patients With Hyperuricosuria and Calcium Oxalate Stones", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hyperuricosuria", "Kidney Stones" ], "interventions": [ { "name": "Febuxostat", "type": "DRUG" }, { "name": "Allopurinol", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 99, "start_date": "2010-02", "completion_date": "2011-11", "has_results": true, "last_update_posted_date": "2013-02-15", "last_synced_at": "2026-09-21T16:46:09.789Z", "location_count": 28, "location_summary": "Birmingham, Alabama • Anchorage, Alaska • Tucson, Arizona + 25 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Anchorage", "state": "Alaska" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Costa Mesa", "state": "California" }, { "city": "Orange", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01077284" }, { "nct_id": "NCT03226899", "title": "A Phase 4 Safety and Efficacy Study to Evaluate Lesinurad 200 mg in Participants With Gout and Renal Impairment", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Gout", "Chronic Kidney Disease (CKD)" ], "interventions": [ { "name": "Lesinurad", "type": "DRUG" }, { "name": "XOI", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "colchicine", "type": "DRUG" }, { "name": "corticosteroids", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Ironwood Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 242, "start_date": "2017-07-19", "completion_date": "2019-02-25", "has_results": true, "last_update_posted_date": "2021-11-04", "last_synced_at": "2026-09-21T16:46:09.789Z", "location_count": 70, "location_summary": "Birmingham, Alabama • Tucson, Arizona • Covina, California + 59 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Covina", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "Sacramento", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03226899" }, { "nct_id": "NCT01496469", "title": "Effect of Febuxostat on Blood Pressure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Febuxostat", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 121, "start_date": "2012-02", "completion_date": "2014-08", "has_results": true, "last_update_posted_date": "2015-08-31", "last_synced_at": "2026-09-21T16:46:09.789Z", "location_count": 45, "location_summary": "Foley, Alabama • Buena Park, California • Carmichael, California + 42 more", "locations": [ { "city": "Foley", "state": "Alabama" }, { "city": "Buena Park", "state": "California" }, { "city": "Carmichael", "state": "California" }, { "city": "Fresno", "state": "California" }, { "city": "Irvine", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01496469" }, { "nct_id": "NCT01078389", "title": "Effect of Febuxostat on Joint Damage in Hyperuricemic Subjects With Early Gout", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Joint Damage" ], "interventions": [ { "name": "Febuxostat", "type": "DRUG" }, { "name": "Placebo for Febuxostat", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 314, "start_date": "2010-03", "completion_date": "2013-09", "has_results": true, "last_update_posted_date": "2014-09-10", "last_synced_at": "2026-09-21T16:46:09.789Z", "location_count": 56, "location_summary": "Mesa, Arizona • Tucson, Arizona • Burbank, California + 53 more", "locations": [ { "city": "Mesa", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Burbank", "state": "California" }, { "city": "Carmichael", "state": "California" }, { "city": "Costa Mesa", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01078389" }, { "nct_id": "NCT01763996", "title": "The Influence of Febuxostat on Coronary Artery Endothelial Dysfunction in Participants With Chronic Stable Angina", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Coronary Artery Disease" ], "interventions": [ { "name": "Febuxostat", "type": "DRUG" }, { "name": "Febuxostat placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 30, "start_date": "2013-05", "completion_date": "2015-04", "has_results": true, "last_update_posted_date": "2016-04-13", "last_synced_at": "2026-09-21T16:46:09.789Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT01763996" }, { "nct_id": "NCT01549977", "title": "Effect of Febuxostat Compared to Placebo on Exercise Tolerance in Participants With Chronic Stable Angina", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Angina" ], "interventions": [ { "name": "Febuxostat", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 1, "start_date": "2012-07", "completion_date": "2012-11", "has_results": true, "last_update_posted_date": "2013-12-20", "last_synced_at": "2026-09-21T16:46:09.789Z", "location_count": 21, "location_summary": "Carmichael, California • Fresno, California • Irvine, California + 18 more", "locations": [ { "city": "Carmichael", "state": "California" }, { "city": "Fresno", "state": "California" }, { "city": "Irvine", "state": "California" }, { "city": "Paramount", "state": "California" }, { "city": "Sacramento", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01549977" }, { "nct_id": "NCT02139046", "title": "Efficacy and Safety of Extended Release and Immediate Release Febuxostat in Participants With Gout", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Gout" ], "interventions": [ { "name": "Febuxostat IR", "type": "DRUG" }, { "name": "Febuxostat XR", "type": "DRUG" }, { "name": "Febuxostat placebo", "type": "DRUG" }, { "name": "Colchicine", "type": "DRUG" }, { "name": "Naproxen", "type": "DRUG" }, { "name": "Lansoprazole", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1790, "start_date": "2014-04", "completion_date": "2015-11", "has_results": true, "last_update_posted_date": "2016-11-03", "last_synced_at": "2026-09-21T16:46:09.789Z", "location_count": 192, "location_summary": "Binghamton, Alabama • Birmingham, Alabama • Huntsville, Alabama + 189 more", "locations": [ { "city": "Binghamton", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Gilbert", "state": "Arizona" }, { "city": "Glendale", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT02139046" }, { "nct_id": "NCT01082640", "title": "Effect of Febuxostat on Renal Function in Patients With Gout and Moderate to Severe Renal Impairment", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Renal Impairment" ], "interventions": [ { "name": "Febuxostat", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 96, "start_date": "2010-04", "completion_date": "2012-05", "has_results": true, "last_update_posted_date": "2013-09-25", "last_synced_at": "2026-09-21T16:46:09.789Z", "location_count": 58, "location_summary": "Birmingham, Alabama • Peoria, Arizona • Sierra Vista, Arizona + 55 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Peoria", "state": "Arizona" }, { "city": "Sierra Vista", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01082640" } ] }