{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+for+allopurinol&page=2", "query": { "intervention": "Placebo for allopurinol", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 35, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+for+allopurinol&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+for+allopurinol&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-07T02:08:28.696Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01265264", "title": "Study to Evaluate sUA Lowering Activity, Safety and Efficacy of Oral Ulodesine Added to Allopurinol", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Gout", "Hyperuricemia", "Arthritis", "Joint Disease" ], "interventions": [ { "name": "ulodesine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "BioCryst Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "69 Years", "sex": "ALL", "summary": "18 Years to 69 Years" }, "enrollment_count": 279, "start_date": "2010-12", "completion_date": "2013-02", "has_results": false, "last_update_posted_date": "2013-11-20", "last_synced_at": "2026-10-07T02:08:28.696Z", "location_count": 54, "location_summary": "Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 51 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT01265264" }, { "nct_id": "NCT01129648", "title": "Study to Evaluate sUA-Lowering Activity, Safety & PK Interaction of Oral BCX4208 & Allopurinol Admin. in Subjects w/Gout", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Gout" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Allopurinol", "type": "DRUG" }, { "name": "BCX4208", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "BioCryst Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "69 Years", "sex": "ALL", "summary": "18 Years to 69 Years" }, "enrollment_count": 87, "start_date": "2010-05", "completion_date": "2010-11", "has_results": false, "last_update_posted_date": "2012-01-23", "last_synced_at": "2026-10-07T02:08:28.696Z", "location_count": 18, "location_summary": "Scottsdale, Arizona • Irvine, California • South Miami, Florida + 15 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Irvine", "state": "California" }, { "city": "South Miami", "state": "Florida" }, { "city": "Honolulu", "state": "Hawaii" }, { "city": "Boise", "state": "Idaho" } ], "official_url": "https://clinicaltrials.gov/study/NCT01129648" }, { "nct_id": "NCT01407874", "title": "A Randomized, Double-Blind, Dose-Response Study of the Safety and Uric Acid Effects of Oral Ulodesine Added to Allopurinol in Subjects With Gout and Concomitant Moderate Renal Insufficiency", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Gout", "Hyperuricemia", "Arthritis", "Joint Disease", "Renal Insufficiency" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Ulodesine (BCX4208) 5 mg", "type": "DRUG" }, { "name": "Ulodesine (BCX4208) 10 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "BioCryst Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "69 Years", "sex": "ALL", "summary": "18 Years to 69 Years" }, "enrollment_count": 20, "start_date": "2011-09", "completion_date": "2012-07", "has_results": false, "last_update_posted_date": "2013-11-20", "last_synced_at": "2026-10-07T02:08:28.696Z", "location_count": 10, "location_summary": "Mobile, Alabama • Peoria, Arizona • Irvine, California + 7 more", "locations": [ { "city": "Mobile", "state": "Alabama" }, { "city": "Peoria", "state": "Arizona" }, { "city": "Irvine", "state": "California" }, { "city": "Oldsmar", "state": "Florida" }, { "city": "Honolulu", "state": "Hawaii" } ], "official_url": "https://clinicaltrials.gov/study/NCT01407874" }, { "nct_id": "NCT04327024", "title": "Study of Verinurad in Heart Failure With Preserved Ejection Fraction", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Heart Failure With Preserved Ejection Fraction (HFpEF)" ], "interventions": [ { "name": "Verinurad", "type": "DRUG" }, { "name": "Allopurinol", "type": "DRUG" }, { "name": "Placebo for verinurad", "type": "DRUG" }, { "name": "Placebo for allopurinol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AstraZeneca", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "130 Years", "sex": "ALL", "summary": "40 Years to 130 Years" }, "enrollment_count": 159, "start_date": "2020-05-19", "completion_date": "2022-04-29", "has_results": true, "last_update_posted_date": "2023-06-29", "last_synced_at": "2026-10-07T02:08:28.696Z", "location_count": 8, "location_summary": "Granada Hills, California • Northridge, California • Torrance, California + 5 more", "locations": [ { "city": "Granada Hills", "state": "California" }, { "city": "Northridge", "state": "California" }, { "city": "Torrance", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Pembroke Pines", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04327024" }, { "nct_id": "NCT01001338", "title": "Allopurinol Combination Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Gout" ], "interventions": [ { "name": "RDEA594", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Allopurinol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Ardea Biosciences, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 227, "start_date": "2009-10", "completion_date": "2016-08", "has_results": false, "last_update_posted_date": "2017-01-24", "last_synced_at": "2026-10-07T02:08:28.696Z", "location_count": 25, "location_summary": "Phoenix, Arizona • La Jolla, California • Los Angeles, California + 22 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Stanford", "state": "California" }, { "city": "Boca Raton", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01001338" }, { "nct_id": "NCT00987415", "title": "Using Allopurinol to Relieve Symptoms in Patients With Heart Failure and High Uric Acid Levels", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Heart Failure", "Elevated Serum Uric Acid" ], "interventions": [ { "name": "allopurinol", "type": "DRUG" }, { "name": "sugar pill", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 253, "start_date": "2010-05", "completion_date": "2014-06", "has_results": true, "last_update_posted_date": "2014-11-04", "last_synced_at": "2026-10-07T02:08:28.696Z", "location_count": 9, "location_summary": "Atlanta, Georgia • Boston, Massachusetts • Minneapolis, Minnesota + 6 more", "locations": [ { "city": "Atlanta", "state": "Georgia" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Minneapolis", "state": "Minnesota" }, { "city": "Rochester", "state": "Minnesota" }, { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00987415" }, { "nct_id": "NCT01332799", "title": "Xanthine Oxidase Inhibition in Renal Transplant Recipients", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Complications of Renal Transplant" ], "interventions": [ { "name": "allopurinol or placebo", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Roberto S Kalil", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 20, "start_date": "2011-02", "completion_date": "2018-08-10", "has_results": true, "last_update_posted_date": "2019-10-15", "last_synced_at": "2026-10-07T02:08:28.696Z", "location_count": 1, "location_summary": "Iowa City, Iowa", "locations": [ { "city": "Iowa City", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT01332799" }, { "nct_id": "NCT00288184", "title": "Uric Acid in Essential Hypertension in Children", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Essential Hypertension" ], "interventions": [ { "name": "Allopurinol", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "18 Years", "sex": "ALL", "summary": "12 Years to 18 Years" }, "enrollment_count": 30, "start_date": "2004-09", "completion_date": "2007-08", "has_results": false, "last_update_posted_date": "2017-09-14", "last_synced_at": "2026-10-07T02:08:28.696Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00288184" }, { "nct_id": "NCT03226899", "title": "A Phase 4 Safety and Efficacy Study to Evaluate Lesinurad 200 mg in Participants With Gout and Renal Impairment", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Gout", "Chronic Kidney Disease (CKD)" ], "interventions": [ { "name": "Lesinurad", "type": "DRUG" }, { "name": "XOI", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "colchicine", "type": "DRUG" }, { "name": "corticosteroids", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Ironwood Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 242, "start_date": "2017-07-19", "completion_date": "2019-02-25", "has_results": true, "last_update_posted_date": "2021-11-04", "last_synced_at": "2026-10-07T02:08:28.696Z", "location_count": 70, "location_summary": "Birmingham, Alabama • Tucson, Arizona • Covina, California + 59 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Covina", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "Sacramento", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03226899" }, { "nct_id": "NCT05818085", "title": "Phase 2b/3 Study to Assess ABP-671 a Novel URAT1 Inhibitor in Participants With Gout", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Gout" ], "interventions": [ { "name": "ABP-671", "type": "DRUG" }, { "name": "Allopurinol", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Atom Therapeutics Co., Ltd", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "19 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "19 Years to 75 Years" }, "enrollment_count": 300, "start_date": "2023-08-11", "completion_date": "2025-03-30", "has_results": false, "last_update_posted_date": "2025-12-22", "last_synced_at": "2026-10-07T02:08:28.696Z", "location_count": 35, "location_summary": "Tempe, Arizona • Tuscon, Arizona • Anaheim, California + 27 more", "locations": [ { "city": "Tempe", "state": "Arizona" }, { "city": "Tuscon", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "Brooksville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05818085" } ] }