{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+for+apixaban", "query": { "intervention": "Placebo for apixaban" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 23, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+for+apixaban&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-21T15:43:17.522Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02179177", "title": "Apixaban in Patients With Sickle Cell Disease", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Vaso-occlusive Crisis", "Reduction in Hospitalizations", "Sickle Cell Disease" ], "interventions": [ { "name": "Apixaban", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Nirmish Shah", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 16, "start_date": "2015-01", "completion_date": "2017-09-03", "has_results": true, "last_update_posted_date": "2020-03-11", "last_synced_at": "2026-09-21T15:43:17.522Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02179177" }, { "nct_id": "NCT00643201", "title": "Efficacy and Safety Study of Apixaban for the Treatment of Deep Vein Thrombosis or Pulmonary Embolism", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Venous Thrombosis" ], "interventions": [ { "name": "Enoxaparin", "type": "DRUG" }, { "name": "warfarin", "type": "DRUG" }, { "name": "Placebo for apixaban", "type": "DRUG" }, { "name": "Placebo for enoxaparin", "type": "DRUG" }, { "name": "Placebo for warfarin", "type": "DRUG" }, { "name": "apixaban", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 5614, "start_date": "2008-07", "completion_date": "2013-03", "has_results": true, "last_update_posted_date": "2014-04-21", "last_synced_at": "2026-09-21T15:43:17.522Z", "location_count": 73, "location_summary": "Birmingham, Alabama • Mobile, Alabama • Fort Smith, Arkansas + 68 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Fort Smith", "state": "Arkansas" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Banning", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00643201" }, { "nct_id": "NCT03310021", "title": "A Healthy Volunteer Pharmacokinetics (PK)/Pharmacodynamics (PD), Safety and Tolerability Study of Andexanet in Healthy Japanese and Caucasian Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Bleeding" ], "interventions": [ { "name": "Andexanet alfa", "type": "BIOLOGICAL" }, { "name": "Apixaban", "type": "DRUG" }, { "name": "Rivaroxaban", "type": "DRUG" }, { "name": "Edoxaban", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "Portola Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 108, "start_date": "2017-08-28", "completion_date": "2019-08-13", "has_results": true, "last_update_posted_date": "2023-02-24", "last_synced_at": "2026-09-21T15:43:17.522Z", "location_count": 1, "location_summary": "Cypress, California", "locations": [ { "city": "Cypress", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03310021" }, { "nct_id": "NCT00457002", "title": "Study of Apixaban for the Prevention of Thrombosis-related Events in Patients With Acute Medical Illness", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Venous Thrombosis", "Pulmonary Embolism" ], "interventions": [ { "name": "Apixaban", "type": "DRUG" }, { "name": "Enoxaparin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 6758, "start_date": "2007-06", "completion_date": "2011-05", "has_results": true, "last_update_posted_date": "2015-12-08", "last_synced_at": "2026-09-21T15:43:17.522Z", "location_count": 48, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 42 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Fort Smith", "state": "Arkansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00457002" }, { "nct_id": "NCT03251482", "title": "A Study to Evaluate the Safety and Efficacy of Intravenous JNJ-64179375 Versus Oral Apixaban in Participants Undergoing Elective Total Knee Replacement Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "VTE Prophylaxis With Anticoagulation After Total Knee Replacement Surgery" ], "interventions": [ { "name": "JNJ-64179375 0.3 mg/kg", "type": "DRUG" }, { "name": "JNJ-64179375 0.6 mg/kg", "type": "DRUG" }, { "name": "JNJ-64179375 1.2 mg/kg", "type": "DRUG" }, { "name": "JNJ-64179375 (Dose to be Determined)", "type": "DRUG" }, { "name": "JNJ-64179375 A mg/kg", "type": "DRUG" }, { "name": "JNJ-64179375 B mg/kg", "type": "DRUG" }, { "name": "JNJ-64179375 C mg/kg", "type": "DRUG" }, { "name": "JNJ-64179375 D mg/kg", "type": "DRUG" }, { "name": "Placebo JNJ-64179375", "type": "DRUG" }, { "name": "Apixaban placebo", "type": "DRUG" }, { "name": "Apixaban 2.5 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 308, "start_date": "2017-11-13", "completion_date": "2018-11-05", "has_results": true, "last_update_posted_date": "2019-11-25", "last_synced_at": "2026-09-21T15:43:17.522Z", "location_count": 7, "location_summary": "Phoenix, Arizona • Torrance, California • Englewood, Colorado + 4 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Torrance", "state": "California" }, { "city": "Englewood", "state": "Colorado" }, { "city": "DeLand", "state": "Florida" }, { "city": "Pensacola", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03251482" }, { "nct_id": "NCT04168203", "title": "Extended-Duration Low-Intensity Apixaban to Prevent Recurrence in High-Risk Patients With Provoked Venous Thromboembolism", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Deep Vein Thrombosis", "Pulmonary Embolism", "Venous Thromboembolism" ], "interventions": [ { "name": "Apixaban 2.5 MG", "type": "DRUG" }, { "name": "Placebo oral tablet", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 600, "start_date": "2021-03-01", "completion_date": "2025-04-08", "has_results": true, "last_update_posted_date": "2025-11-14", "last_synced_at": "2026-09-21T15:43:17.522Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04168203" }, { "nct_id": "NCT00831441", "title": "Phase III Acute Coronary Syndrome", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Acute Coronary Syndrome" ], "interventions": [ { "name": "Apixaban", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 7484, "start_date": "2009-03", "completion_date": "2011-03", "has_results": true, "last_update_posted_date": "2016-01-27", "last_synced_at": "2026-09-21T15:43:17.522Z", "location_count": 221, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 179 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Fort Smith", "state": "Arkansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00831441" }, { "nct_id": "NCT00320255", "title": "A Phase 2 Pilot Study of Apixaban for the Prevention of Thromboembolic Events in Patients With Advanced (Metastatic) Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Thrombosis", "Cancer", "Pulmonary Embolism" ], "interventions": [ { "name": "Apixaban", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 130, "start_date": "2006-06", "completion_date": "2009-01", "has_results": true, "last_update_posted_date": "2016-08-16", "last_synced_at": "2026-09-21T15:43:17.522Z", "location_count": 8, "location_summary": "Tucson, Arizona • Los Angeles, California • Boston, Massachusetts + 4 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Las Vegas", "state": "Nevada" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00320255" }, { "nct_id": "NCT00633893", "title": "Efficacy and Safety Study of Apixaban for Extended Treatment of Deep Vein Thrombosis or Pulmonary Embolism", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Venous Thrombosis" ], "interventions": [ { "name": "Apixaban", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 2711, "start_date": "2008-05", "completion_date": "2012-08", "has_results": true, "last_update_posted_date": "2013-11-25", "last_synced_at": "2026-09-21T15:43:17.522Z", "location_count": 87, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Tempe, Arizona + 82 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tempe", "state": "Arizona" }, { "city": "Fort Smith", "state": "Arkansas" }, { "city": "Banning", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00633893" }, { "nct_id": "NCT04593784", "title": "Study of Ciraparantag for Reversal of Anticoagulation Induced by Edoxaban, Apixaban or Rivaroxaban in Healthy Adults", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Ciraparantag", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Point-of-Care Coagulometer (investigational device)", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "AMAG Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 41, "start_date": "2021-10-13", "completion_date": "2023-08-26", "has_results": true, "last_update_posted_date": "2026-04-20", "last_synced_at": "2026-09-21T15:43:17.522Z", "location_count": 3, "location_summary": "South Miami, Florida • Secaucus, New Jersey • San Antonio, Texas", "locations": [ { "city": "South Miami", "state": "Florida" }, { "city": "Secaucus", "state": "New Jersey" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04593784" } ] }