{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+for+sitagliptin&page=2", "query": { "intervention": "Placebo for sitagliptin", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 63, "total_pages": 7, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+for+sitagliptin&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+for+sitagliptin&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-01T05:14:10.395Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02647320", "title": "12-Week Study of DS-8500a in Subjects With Type 2 Diabetes Mellitus on Metformin", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Type 2 Diabetes Mellitus" ], "interventions": [ { "name": "Sitagliptin 100 mg", "type": "DRUG" }, { "name": "DS-8500a 25mg", "type": "DRUG" }, { "name": "Placebo Tablet", "type": "DRUG" }, { "name": "Placebo Capsule", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 298, "start_date": "2016-01", "completion_date": "2017-01-31", "has_results": true, "last_update_posted_date": "2019-02-25", "last_synced_at": "2026-10-01T05:14:10.395Z", "location_count": 48, "location_summary": "Birmingham, Alabama • Litchfield Park, Arizona • Tempe, Arizona + 41 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Litchfield Park", "state": "Arizona" }, { "city": "Tempe", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Chino", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02647320" }, { "nct_id": "NCT02111096", "title": "A Study of LY2409021 in Participants With Type 2 Diabetes Mellitus", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Diabetes Mellitus, Type 2" ], "interventions": [ { "name": "LY2409021", "type": "DRUG" }, { "name": "Sitagliptin", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Metformin", "type": "DRUG" }, { "name": "Sulfonylurea", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eli Lilly and Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "79 Years", "sex": "ALL", "summary": "18 Years to 79 Years" }, "enrollment_count": 174, "start_date": "2014-04", "completion_date": "2015-09", "has_results": true, "last_update_posted_date": "2019-10-09", "last_synced_at": "2026-10-01T05:14:10.395Z", "location_count": 26, "location_summary": "Concord, California • Fresno, California • Los Angeles, California + 19 more", "locations": [ { "city": "Concord", "state": "California" }, { "city": "Fresno", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02111096" }, { "nct_id": "NCT03115112", "title": "Safety and Efficacy of Bexagliflozin Compared to Sitagliptin as Add-on Therapy to Metformin in Type 2 Diabetes Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Type 2 Diabetes Mellitus" ], "interventions": [ { "name": "Bexagliflozin", "type": "DRUG" }, { "name": "Sitagliptin", "type": "DRUG" }, { "name": "Placebo for sitagliptin", "type": "DRUG" }, { "name": "Placebo for bexagliflozin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Theracos", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 386, "start_date": "2017-10-12", "completion_date": "2018-10-31", "has_results": true, "last_update_posted_date": "2021-06-22", "last_synced_at": "2026-10-01T05:14:10.395Z", "location_count": 10, "location_summary": "Lincoln, California • Long Beach, California • San Dimas, California + 7 more", "locations": [ { "city": "Lincoln", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "San Dimas", "state": "California" }, { "city": "Port Orange", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT03115112" }, { "nct_id": "NCT01619332", "title": "Clinical Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LEZ763", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Type II Diabetes" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Sitagliptin", "type": "DRUG" }, { "name": "LEZ763", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 220, "start_date": "2012-03", "completion_date": "2013-09", "has_results": false, "last_update_posted_date": "2020-12-17", "last_synced_at": "2026-10-01T05:14:10.395Z", "location_count": 6, "location_summary": "Chula Vista, California • Miami, Florida • Orlando, Florida + 3 more", "locations": [ { "city": "Chula Vista", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Orlando", "state": "Florida" }, { "city": "Cincinnati", "state": "Ohio" }, { "city": "Knoxville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT01619332" }, { "nct_id": "NCT01549964", "title": "Comparison of Fasiglifam (TAK-875) to Placebo and Sitagliptin in Combination With Metformin in Participants With Type 2 Diabetes", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Glycemic Control" ], "interventions": [ { "name": "Fasiglifam (TAK-875)", "type": "DRUG" }, { "name": "Sitagliptin", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 916, "start_date": "2012-04", "completion_date": "2014-03", "has_results": true, "last_update_posted_date": "2016-06-02", "last_synced_at": "2026-10-01T05:14:10.395Z", "location_count": 58, "location_summary": "Muscle Shoals, Alabama • Mesa, Arizona • Peoria, Arizona + 55 more", "locations": [ { "city": "Muscle Shoals", "state": "Alabama" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Peoria", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Chula Vista", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01549964" }, { "nct_id": "NCT01512797", "title": "Treatment of Diabetes After Gastric Bypass With Sitagliptin", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Type 2 Diabetes Mellitus" ], "interventions": [ { "name": "Sitagliptin phosphate", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Blandine Laferrere", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 37, "start_date": "2012-07", "completion_date": "2016-08", "has_results": true, "last_update_posted_date": "2019-01-22", "last_synced_at": "2026-10-01T05:14:10.395Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01512797" }, { "nct_id": "NCT00820573", "title": "Mechanisms of Glucose Lowering Effects of Sitagliptin and Metformin Alone and in Combination in Patients With T2DM", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Diabetes" ], "interventions": [ { "name": "Sitagliptin", "type": "DRUG" }, { "name": "Metformin", "type": "DRUG" }, { "name": "Sitagliptin + Metformin", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The University of Texas Health Science Center at San Antonio", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 16, "start_date": "2009-10", "completion_date": "2012-10", "has_results": true, "last_update_posted_date": "2013-12-13", "last_synced_at": "2026-10-01T05:14:10.395Z", "location_count": 1, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00820573" }, { "nct_id": "NCT02122380", "title": "The Effect of Dipeptidyl Peptidase 4 Inhibition on Growth Hormone Secretion in Women With Polycystic Ovarian Syndrome", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Polycystic Ovary Syndrome" ], "interventions": [ { "name": "Sitagliptin", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vanderbilt University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "40 Years", "sex": "FEMALE", "summary": "18 Years to 40 Years · Female only" }, "enrollment_count": 23, "start_date": "2016-02", "completion_date": "2019-08-01", "has_results": true, "last_update_posted_date": "2020-05-08", "last_synced_at": "2026-10-01T05:14:10.395Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT02122380" }, { "nct_id": "NCT01338870", "title": "Study of Safety and Efficacy of PF-04991532 in Subjects With Type 2 Diabetes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Diabetes Mellitus, Type 2" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "25 mg PF-04991532", "type": "DRUG" }, { "name": "75 mg PF-04991532", "type": "DRUG" }, { "name": "150 mg PF-04991532", "type": "DRUG" }, { "name": "300 mg PF-04991532", "type": "DRUG" }, { "name": "Sitagliptin 100 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 301, "start_date": "2011-06", "completion_date": "2012-03", "has_results": true, "last_update_posted_date": "2013-04-23", "last_synced_at": "2026-10-01T05:14:10.395Z", "location_count": 25, "location_summary": "Little Rock, Arkansas • Roseville, California • Denver, Colorado + 22 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Roseville", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Coral Gables", "state": "Florida" }, { "city": "Ocala", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01338870" }, { "nct_id": "NCT01475461", "title": "Phase 2 Study To Evaluate Safety And Efficacy Of Investigational Drug - PF04937319 In Patients With Type 2 Diabetes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Type 2 Diabetes Mellitus" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "PF-04937319 - 3mg", "type": "DRUG" }, { "name": "PF-04937319 - 20mg", "type": "DRUG" }, { "name": "PF-04937319 - 50mg", "type": "DRUG" }, { "name": "PF-04937319 - 100mg", "type": "DRUG" }, { "name": "Sitagliptin - 100mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 345, "start_date": "2011-11", "completion_date": "2013-01", "has_results": true, "last_update_posted_date": "2017-01-31", "last_synced_at": "2026-10-01T05:14:10.395Z", "location_count": 24, "location_summary": "Anaheim, California • Los Angeles, California • Spring Valley, California + 18 more", "locations": [ { "city": "Anaheim", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Spring Valley", "state": "California" }, { "city": "Belleview", "state": "Florida" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01475461" } ] }