{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+naltrexone", "query": { "intervention": "Placebo naltrexone" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 193, "total_pages": 20, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+naltrexone&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-10T11:02:29.591Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02543944", "title": "Improving Treatment Outcomes for Prescription Opioid Dependence", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Drug Dependence" ], "interventions": [ { "name": "Gabapentin", "type": "DRUG" }, { "name": "Buprenorphine", "type": "DRUG" }, { "name": "Clonidine", "type": "DRUG" }, { "name": "Naltrexone (oral)", "type": "DRUG" }, { "name": "Naltrexone (depot)", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Arkansas", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 117, "start_date": "2016-02", "completion_date": "2021-05-31", "has_results": true, "last_update_posted_date": "2022-07-28", "last_synced_at": "2026-09-10T11:02:29.591Z", "location_count": 1, "location_summary": "Little Rock, Arkansas", "locations": [ { "city": "Little Rock", "state": "Arkansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02543944" }, { "nct_id": "NCT03132571", "title": "Naltrexone-Bupropion Versus Placebo-Bupropion for Weight Loss in Schizophrenia", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Schizophrenia", "Diabetes Mellitus, Type 2", "Obesity" ], "interventions": [ { "name": "Naltrexone", "type": "DRUG" }, { "name": "Bupropion", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 5, "start_date": "2017-06-01", "completion_date": "2018-07-31", "has_results": true, "last_update_posted_date": "2019-08-07", "last_synced_at": "2026-09-10T11:02:29.591Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT03132571" }, { "nct_id": "NCT00270231", "title": "Effects of Naltrexone on Nicotine Reinforcement", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Tobacco Dependence" ], "interventions": [ { "name": "Naltrexone", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 64, "start_date": "2004-03", "completion_date": "2005-10", "has_results": true, "last_update_posted_date": "2013-12-10", "last_synced_at": "2026-09-10T11:02:29.591Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00270231" }, { "nct_id": "NCT02330419", "title": "Better Than Study: Targeting Heavy Alcohol Use With Naltrexone Among Men Who Have Sex With Men (MSM)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Binge Drinking", "HIV" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Naltrexone", "type": "DRUG" }, { "name": "Medical Management (MM) counseling for alcohol use:", "type": "BEHAVIORAL" }, { "name": "Urinalysis for novel alcohol biochemical markers:", "type": "DIAGNOSTIC_TEST" }, { "name": "Behavioral survey measurements:", "type": "BEHAVIORAL" }, { "name": "Dried Blood Spot (DSB) Testing for Phosphatidylethanol", "type": "DIAGNOSTIC_TEST" }, { "name": "Ecological Momentary Assessment", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL", "DIAGNOSTIC_TEST" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "MALE", "summary": "18 Years to 70 Years · Male only" }, "enrollment_count": 120, "start_date": "2015-04", "completion_date": "2021-01", "has_results": true, "last_update_posted_date": "2025-04-20", "last_synced_at": "2026-09-10T11:02:29.591Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02330419" }, { "nct_id": "NCT02026011", "title": "Naltrexone for Individuals of East Asian Descent", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Alcohol Use Disorder" ], "interventions": [ { "name": "Naltrexone", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, Los Angeles", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "21 Years to 65 Years" }, "enrollment_count": 87, "start_date": "2013-12", "completion_date": "2016-09", "has_results": true, "last_update_posted_date": "2019-07-17", "last_synced_at": "2026-09-10T11:02:29.591Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02026011" }, { "nct_id": "NCT00420992", "title": "A Study of Embeda (Kadian NT, ALO-01) in Subjects With Pain Due to Osteoarthritis of the Hip or Knee", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Osteoarthritis", "Chronic Pain" ], "interventions": [ { "name": "ALO-01 (Morphine Sulfate Plus Naltrexone Hydrochloride Extended Release)", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 547, "start_date": "2006-12", "completion_date": "2007-11", "has_results": true, "last_update_posted_date": "2013-09-20", "last_synced_at": "2026-09-10T11:02:29.591Z", "location_count": 81, "location_summary": "Birmingham, Alabama • Mobile, Alabama • Peoria, Arizona + 69 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Peoria", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tempe", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00420992" }, { "nct_id": "NCT02317744", "title": "Treatment of Binge Eating Disorder in Obesity: Naltrexone/ Bupropion Combination Versus Placebo", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Binge Eating Disorder" ], "interventions": [ { "name": "Naltrexone and bupropion combination", "type": "DRUG" }, { "name": "Pill Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "21 Years to 65 Years" }, "enrollment_count": 22, "start_date": "2014-12", "completion_date": "2016-09", "has_results": true, "last_update_posted_date": "2017-12-22", "last_synced_at": "2026-09-10T11:02:29.591Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT02317744" }, { "nct_id": "NCT02726035", "title": "Evaluation of Naltrexone as a Treatment for Self-injurious Behavior", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Self-injurious Behavior", "Self Mutilation" ], "interventions": [ { "name": "Naltrexone", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Western Michigan University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": null, "sex": "ALL", "summary": "13 Years and older" }, "enrollment_count": 0, "start_date": "2014-02-22", "completion_date": "2017-01-04", "has_results": false, "last_update_posted_date": "2017-11-06", "last_synced_at": "2026-09-10T11:02:29.591Z", "location_count": 1, "location_summary": "Kalamazoo, Michigan", "locations": [ { "city": "Kalamazoo", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT02726035" }, { "nct_id": "NCT01057862", "title": "Investigation of Naltrexone for Pathological Gambling", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pathological Gambling" ], "interventions": [ { "name": "Naltrexone", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 9, "start_date": "2009-02", "completion_date": "2017-01", "has_results": true, "last_update_posted_date": "2017-10-13", "last_synced_at": "2026-09-10T11:02:29.591Z", "location_count": 3, "location_summary": "Middletown, Connecticut • New Haven, Connecticut", "locations": [ { "city": "Middletown", "state": "Connecticut" }, { "city": "New Haven", "state": "Connecticut" }, { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT01057862" }, { "nct_id": "NCT00775229", "title": "Naltrexone in the Treatment of Trichotillomania", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Trichotillomania" ], "interventions": [ { "name": "Naltrexone", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 51, "start_date": "2008-08", "completion_date": "2012-12", "has_results": true, "last_update_posted_date": "2023-02-23", "last_synced_at": "2026-09-10T11:02:29.591Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00775229" } ] }