{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+naltrexone&page=8", "query": { "intervention": "Placebo naltrexone", "page": 8 }, "page_size": 10 }, "pagination": { "page": 8, "page_size": 10, "total_count": 193, "total_pages": 20, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+naltrexone&page=9&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+naltrexone&page=7&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-11T11:36:03.995Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05509257", "title": "Naltrexone Neuroimaging in Teens With Eating Disorders", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Eating Disorders", "Binge Eating", "Purging (Eating Disorders)", "Bulimia Nervosa", "Anorexia Nervosa, Atypical" ], "interventions": [ { "name": "Naltrexone", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Children's Mercy Hospital Kansas City", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": "21 Years", "sex": "ALL", "summary": "13 Years to 21 Years" }, "enrollment_count": 60, "start_date": "2022-09-17", "completion_date": "2027-06", "has_results": false, "last_update_posted_date": "2025-11-25", "last_synced_at": "2026-10-11T11:36:03.995Z", "location_count": 1, "location_summary": "Kansas City, Missouri", "locations": [ { "city": "Kansas City", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT05509257" }, { "nct_id": "NCT03660475", "title": "Effect of Topical Naltrexone Ophthalmic Solution on the Signs and Symptoms of Dry Eye in Diabetic Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Dry Eye Disease" ], "interventions": [ { "name": "Naltrexone", "type": "DRUG" }, { "name": "Placebos", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sassani, Joseph S., MD, MHA", "sponsor_class": "INDIV", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2018-07-31", "completion_date": "2018-11-15", "has_results": true, "last_update_posted_date": "2022-12-02", "last_synced_at": "2026-10-11T11:36:03.995Z", "location_count": 1, "location_summary": "Memphis, Tennessee", "locations": [ { "city": "Memphis", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT03660475" }, { "nct_id": "NCT01825447", "title": "A Study to Characterize the Abuse Liability of Intravenous Oxycodone Alone or in Combination With Intravenous Naltrexone in Healthy, Non-Dependent, Recreational Opioid Users", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Oxycodone + Naltrexone", "type": "DRUG" }, { "name": "Oxycodone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 89, "start_date": "2013-07", "completion_date": "2013-09", "has_results": false, "last_update_posted_date": "2013-10-08", "last_synced_at": "2026-10-11T11:36:03.995Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT01825447" }, { "nct_id": "NCT03132571", "title": "Naltrexone-Bupropion Versus Placebo-Bupropion for Weight Loss in Schizophrenia", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Schizophrenia", "Diabetes Mellitus, Type 2", "Obesity" ], "interventions": [ { "name": "Naltrexone", "type": "DRUG" }, { "name": "Bupropion", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 5, "start_date": "2017-06-01", "completion_date": "2018-07-31", "has_results": true, "last_update_posted_date": "2019-08-07", "last_synced_at": "2026-10-11T11:36:03.995Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT03132571" }, { "nct_id": "NCT01723384", "title": "Intermittent Naltrexone Among Polysubstance Users", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Methamphetamine", "Alcohol" ], "interventions": [ { "name": "Intermittent Oral Naltrexone", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "MALE", "summary": "18 Years to 70 Years · Male only" }, "enrollment_count": 30, "start_date": "2013-05", "completion_date": "2014-11", "has_results": true, "last_update_posted_date": "2019-04-23", "last_synced_at": "2026-10-11T11:36:03.995Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01723384" }, { "nct_id": "NCT00831272", "title": "Pharmacogenetic Response to Naltrexone For Alcohol Dependence", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Alcohol Dependence" ], "interventions": [ { "name": "naltrexone", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "David Oslin", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 221, "start_date": "2009-01-05", "completion_date": "2014-01-15", "has_results": true, "last_update_posted_date": "2017-05-11", "last_synced_at": "2026-10-11T11:36:03.995Z", "location_count": 4, "location_summary": "Danville, Pennsylvania • Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania", "locations": [ { "city": "Danville", "state": "Pennsylvania" }, { "city": "Philadelphia", "state": "Pennsylvania" }, { "city": "Philadelphia", "state": "Pennsylvania" }, { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00831272" }, { "nct_id": "NCT00667875", "title": "An Exploratory Study of Naltrexone Plus Aripiprazole for Alcohol Dependence", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Alcohol Dependence" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Naltrexone", "type": "DRUG" }, { "name": "Naltrexone + Aripiprazole", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Medical University of South Carolina", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 65, "start_date": "2008-04", "completion_date": "2011-05", "has_results": true, "last_update_posted_date": "2017-09-29", "last_synced_at": "2026-10-11T11:36:03.995Z", "location_count": 1, "location_summary": "Charleston, South Carolina", "locations": [ { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00667875" }, { "nct_id": "NCT00920829", "title": "Genetic and Brain Mechanisms of Naltrexone's Treatment Efficacy for Alcoholism", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Alcohol Dependence" ], "interventions": [ { "name": "Naltrexone 50 Mg", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Medical University of South Carolina", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 358, "start_date": "2009-06", "completion_date": "2015-12", "has_results": true, "last_update_posted_date": "2018-07-10", "last_synced_at": "2026-10-11T11:36:03.995Z", "location_count": 2, "location_summary": "Charleston, South Carolina", "locations": [ { "city": "Charleston", "state": "South Carolina" }, { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00920829" }, { "nct_id": "NCT00467454", "title": "Naltrexone in the Treatment of Pyromania", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pyromania" ], "interventions": [ { "name": "Naltrexone", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "16 Years to 75 Years" }, "enrollment_count": 0, "start_date": "2007-06", "completion_date": "2010-04", "has_results": false, "last_update_posted_date": "2011-12-14", "last_synced_at": "2026-10-11T11:36:03.995Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00467454" }, { "nct_id": "NCT04547985", "title": "Naltrexone Treatment for Prolonged Grief Disorder (PGD)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Prolonged Grief Disorder" ], "interventions": [ { "name": "Naltrexone HCl 50 MG Oral Tablet", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Weill Medical College of Cornell University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 9, "start_date": "2021-01-05", "completion_date": "2023-10-16", "has_results": true, "last_update_posted_date": "2024-08-28", "last_synced_at": "2026-10-11T11:36:03.995Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04547985" } ] }