{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+rectal+suppository&page=2",
    "query": {
      "intervention": "Placebo rectal suppository",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+rectal+suppository&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-27T05:28:12.878Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03657407",
      "title": "B&O for TLH Post-operative Pain and Nausea",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Hysterectomy",
        "Pain, Postoperative"
      ],
      "interventions": [
        {
          "name": "Belladonna Opium",
          "type": "DRUG"
        },
        {
          "name": "Glycerin Suppository",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Anna Reinert",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 75 Years · Female only"
      },
      "enrollment_count": 56,
      "start_date": "2016-06-01",
      "completion_date": "2017-05-31",
      "has_results": true,
      "last_update_posted_date": "2019-04-02",
      "last_synced_at": "2026-09-27T05:28:12.878Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03657407"
    },
    {
      "nct_id": "NCT04469686",
      "title": "Phase 3 Study to Evaluate the Safety and Efficacy of Hydrocortisone Acetate Suppositories",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Ulcerative Proctitis"
      ],
      "interventions": [
        {
          "name": "Twice daily 90 mg hydrocortisone acetate suppository administered with Sephure applicator",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Once daily 90 mg hydrocortisone acetate or placebo suppository administered with Sephure applicator",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Twice daily placebo suppository administered with Sephure applicator",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Cristcot HCA LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2020-12-10",
      "completion_date": "2024-09-19",
      "has_results": true,
      "last_update_posted_date": "2026-08-06",
      "last_synced_at": "2026-09-27T05:28:12.878Z",
      "location_count": 51,
      "location_summary": "Huntsville, Alabama • Apple Valley, California • Camarillo, California + 40 more",
      "locations": [
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Apple Valley",
          "state": "California"
        },
        {
          "city": "Camarillo",
          "state": "California"
        },
        {
          "city": "El Cajon",
          "state": "California"
        },
        {
          "city": "Lancaster",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04469686"
    },
    {
      "nct_id": "NCT04198233",
      "title": "Impact of Placement of a Diazepam Suppository on Early Postoperative Pain Following Pelvic Reconstructive Surgery",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Postoperative Pain"
      ],
      "interventions": [
        {
          "name": "Diazepam",
          "type": "DRUG"
        },
        {
          "name": "Placebos",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "TriHealth Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 80 Years · Female only"
      },
      "enrollment_count": 130,
      "start_date": "2020-02-12",
      "completion_date": "2022-12",
      "has_results": false,
      "last_update_posted_date": "2020-07-23",
      "last_synced_at": "2026-09-27T05:28:12.878Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04198233"
    },
    {
      "nct_id": "NCT01774604",
      "title": "Rectal Indomethacin to Prevent Post-Endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Post-ERCP Acute Pancreatitis"
      ],
      "interventions": [
        {
          "name": "Indomethacin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Dartmouth-Hitchcock Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 449,
      "start_date": "2013-01",
      "completion_date": "2014-12",
      "has_results": true,
      "last_update_posted_date": "2016-11-04",
      "last_synced_at": "2026-09-27T05:28:12.878Z",
      "location_count": 1,
      "location_summary": "Lebanon, New Hampshire",
      "locations": [
        {
          "city": "Lebanon",
          "state": "New Hampshire"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01774604"
    },
    {
      "nct_id": "NCT00820612",
      "title": "Rectal Indomethacin in the Prevention of Post-endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis in High Risk Patients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Post-ERCP Pancreatitis"
      ],
      "interventions": [
        {
          "name": "Indomethacin",
          "type": "DRUG"
        },
        {
          "name": "Placebo suppositories",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 602,
      "start_date": "2009-01",
      "completion_date": "2011-07",
      "has_results": true,
      "last_update_posted_date": "2013-02-28",
      "last_synced_at": "2026-09-27T05:28:12.878Z",
      "location_count": 4,
      "location_summary": "Indianapolis, Indiana • Lexington, Kentucky • Ann Arbor, Michigan + 1 more",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00820612"
    },
    {
      "nct_id": "NCT01271855",
      "title": "Assessing Maternal Post-partum Pain With Suppositories",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Belladonna and opioid suppository",
          "type": "DRUG"
        },
        {
          "name": "Glycerin Suppository",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Loyola University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 100,
      "start_date": "2009-07-22",
      "completion_date": "2011-09-29",
      "has_results": true,
      "last_update_posted_date": "2018-03-07",
      "last_synced_at": "2026-09-27T05:28:12.878Z",
      "location_count": 2,
      "location_summary": "Maywood, Illinois • Melrose Park, Illinois",
      "locations": [
        {
          "city": "Maywood",
          "state": "Illinois"
        },
        {
          "city": "Melrose Park",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01271855"
    },
    {
      "nct_id": "NCT01233791",
      "title": "Diazepam Vaginal Suppositories for High Tone Pelvic Floor Dysfunction.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Female Patients With High Tone Pelvic Floor Dysfunction"
      ],
      "interventions": [
        {
          "name": "Vaginal Diazepam Suppository",
          "type": "DRUG"
        },
        {
          "name": "Placebo Suppository",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "TriHealth Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 65 Years · Female only"
      },
      "enrollment_count": 48,
      "start_date": "2010-11",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2015-07-10",
      "last_synced_at": "2026-09-27T05:28:12.878Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01233791"
    },
    {
      "nct_id": "NCT05555862",
      "title": "Artesunate Suppositories for the Treatment of HIV-negative Patients With Intra-anal HSIL",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Anal High Grade Squamous Intraepithelial Lesion",
        "Anal Precancerous Condition",
        "AIN 2/3",
        "HPV Infection",
        "Anal Dysplasia",
        "HPV Disease"
      ],
      "interventions": [
        {
          "name": "Artesunate",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Frantz Viral Therapeutics, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 17,
      "start_date": "2023-02-10",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-05-18",
      "last_synced_at": "2026-09-27T05:28:12.878Z",
      "location_count": 2,
      "location_summary": "Chicago, Illinois • New York, New York",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05555862"
    },
    {
      "nct_id": "NCT02600715",
      "title": "Reduction of Bladder Injection Pain With Belladonna Opiate Suppository",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Overactive Bladder",
        "Urinary Urge Incontinence",
        "Urinary Bladder, Neurogenic",
        "Painful Bladder Syndrome"
      ],
      "interventions": [
        {
          "name": "Onabotulinumtoxin A (BoNT)",
          "type": "DRUG"
        },
        {
          "name": "belladonna",
          "type": "DRUG"
        },
        {
          "name": "Morphine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Active B&O suppository of belladonna",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Edgar LeClaire, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 26,
      "start_date": "2015-11",
      "completion_date": "2017-06-26",
      "has_results": true,
      "last_update_posted_date": "2018-09-20",
      "last_synced_at": "2026-09-27T05:28:12.878Z",
      "location_count": 2,
      "location_summary": "Wichita, Kansas",
      "locations": [
        {
          "city": "Wichita",
          "state": "Kansas"
        },
        {
          "city": "Wichita",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02600715"
    },
    {
      "nct_id": "NCT01840228",
      "title": "Vaginal Progesterone for the Prevention of Preterm Birth in Women With Arrested Preterm Labor",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premature Birth",
        "Obstetric Labor, Premature"
      ],
      "interventions": [
        {
          "name": "Micronized progesterone suppository",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 38,
      "start_date": "2013-05",
      "completion_date": "2018-05-07",
      "has_results": true,
      "last_update_posted_date": "2019-06-18",
      "last_synced_at": "2026-09-27T05:28:12.878Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01840228"
    }
  ]
}