{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+to+Palonosetron", "query": { "intervention": "Placebo to Palonosetron" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-28T17:54:05.483Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03578081", "title": "Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic Chemotherapy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Malignant Neoplasm" ], "interventions": [ { "name": "Palonosetron Hydrochloride", "type": "DRUG" }, { "name": "Ondansetron Hydrochloride", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" }, { "name": "Fosaprepitant Dimeglumine", "type": "DRUG" }, { "name": "Olanzapine", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Alliance for Clinical Trials in Oncology", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 690, "start_date": "2018-11-20", "completion_date": "2023-05-01", "has_results": true, "last_update_posted_date": "2025-04-06", "last_synced_at": "2026-09-28T17:54:05.483Z", "location_count": 565, "location_summary": "Birmingham, Alabama • Fairbanks, Alaska • Kingman, Arizona + 372 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Fairbanks", "state": "Alaska" }, { "city": "Kingman", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT03578081" }, { "nct_id": "NCT00952133", "title": "Efficacy of IV Palo With IV Dexamethasone vs IV Palo for Prevention of Immediate & Delayed PONV", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "PONV" ], "interventions": [ { "name": "Palonosetron only", "type": "DRUG" }, { "name": "Palonosetron with Dexamethasone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "NYU Langone Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 118, "start_date": "2009-07", "completion_date": "2011-04", "has_results": true, "last_update_posted_date": "2015-04-17", "last_synced_at": "2026-09-28T17:54:05.483Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00952133" }, { "nct_id": "NCT01442376", "title": "Efficacy and Safety of Palonosetron Intravenous in Prevention of Chemotherapy Induced Nausea and Vomiting in Pediatric Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chemotherapy-Induced Nausea and Vomiting" ], "interventions": [ { "name": "Palonosetron", "type": "DRUG" }, { "name": "Ondansetron", "type": "DRUG" }, { "name": "Placebo to Ondansetron", "type": "DRUG" }, { "name": "Placebo to Palonosetron", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Helsinn Healthcare SA", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "16 Years", "sex": "ALL", "summary": "Up to 16 Years" }, "enrollment_count": 502, "start_date": "2011-09", "completion_date": "2012-11", "has_results": true, "last_update_posted_date": "2014-08-07", "last_synced_at": "2026-09-28T17:54:05.483Z", "location_count": 14, "location_summary": "Little Rock, Arkansas • Duarte, California • Aurora, Colorado + 11 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Duarte", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Wilmington", "state": "Delaware" }, { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01442376" }, { "nct_id": "NCT00343460", "title": "APF530 or Aloxi (Palonosetron Hydrochloride) Combined With Dexamethasone in Preventing Nausea and Vomiting in Patients Receiving Chemotherapy for Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Nausea and Vomiting", "Unspecified Adult Solid Tumor, Protocol Specific" ], "interventions": [ { "name": "APF530", "type": "DRUG" }, { "name": "dexamethasone", "type": "DRUG" }, { "name": "Palonosetron Hydrochloride", "type": "DRUG" }, { "name": "placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Heron Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "120 Years", "sex": "ALL", "summary": "18 Years to 120 Years" }, "enrollment_count": 1428, "start_date": "2006-06", "completion_date": "2009-02", "has_results": true, "last_update_posted_date": "2026-03-02", "last_synced_at": "2026-09-28T17:54:05.483Z", "location_count": 52, "location_summary": "Anniston, Alabama • Glendale, Arizona • Tucson, Arizona + 46 more", "locations": [ { "city": "Anniston", "state": "Alabama" }, { "city": "Glendale", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Anaheim", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00343460" }, { "nct_id": "NCT00553059", "title": "Palonosetron and Dexamethasone With or Without Dronabinol in Preventing Nausea and Vomiting in Patients Receiving Chemotherapy For Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chemotherapy-induced Nausea and Vomiting", "Unspecified Adult Solid Tumor, Protocol Specific" ], "interventions": [ { "name": "dexamethasone", "type": "DRUG" }, { "name": "dronabinol", "type": "DRUG" }, { "name": "palonosetron hydrochloride", "type": "DRUG" }, { "name": "placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 62, "start_date": "2008-05", "completion_date": "2014-08", "has_results": true, "last_update_posted_date": "2020-10-09", "last_synced_at": "2026-09-28T17:54:05.483Z", "location_count": 4, "location_summary": "Springfield, Missouri • Greenville, South Carolina • Houston, Texas + 1 more", "locations": [ { "city": "Springfield", "state": "Missouri" }, { "city": "Greenville", "state": "South Carolina" }, { "city": "Houston", "state": "Texas" }, { "city": "Burlington", "state": "Vermont" } ], "official_url": "https://clinicaltrials.gov/study/NCT00553059" }, { "nct_id": "NCT00903396", "title": "Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy in Patients With Primary Abdominal Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Anal Cancer", "Carcinoma of the Appendix", "Colorectal Cancer", "Extrahepatic Bile Duct Cancer", "Gallbladder Cancer", "Gastric Cancer", "Gastrointestinal Carcinoid Tumor", "Liver Cancer", "Nausea and Vomiting", "Pancreatic Cancer", "Primary Peritoneal Cavity Cancer", "Small Intestine Cancer" ], "interventions": [ { "name": "palonosetron hydrochloride", "type": "DRUG" }, { "name": "placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Alliance for Clinical Trials in Oncology", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 7, "start_date": "2009-09", "completion_date": "2013-05", "has_results": true, "last_update_posted_date": "2017-11-24", "last_synced_at": "2026-09-28T17:54:05.483Z", "location_count": 69, "location_summary": "Scottsdale, Arizona • Jacksonville, Florida • Moline, Illinois + 37 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Moline", "state": "Illinois" }, { "city": "Moline", "state": "Illinois" }, { "city": "Elkhart", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT00903396" }, { "nct_id": "NCT03367572", "title": "Treatment of Refractory Nausea and Vomiting in Patients With Breast Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Breast Carcinoma" ], "interventions": [ { "name": "Dexamethasone", "type": "DRUG" }, { "name": "Laboratory Biomarker Analysis", "type": "OTHER" }, { "name": "Netupitant/Palonosetron Hydrochloride", "type": "DRUG" }, { "name": "Olanzapine", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" }, { "name": "Prochlorperazine", "type": "DRUG" }, { "name": "Quality-of-Life Assessment", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of Rochester NCORP Research Base", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 1363, "start_date": "2018-04-19", "completion_date": "2024-04-13", "has_results": true, "last_update_posted_date": "2025-09-25", "last_synced_at": "2026-09-28T17:54:05.483Z", "location_count": 18, "location_summary": "Honolulu, Hawaii • Decatur, Illinois • New Orleans, Louisiana + 15 more", "locations": [ { "city": "Honolulu", "state": "Hawaii" }, { "city": "Decatur", "state": "Illinois" }, { "city": "New Orleans", "state": "Louisiana" }, { "city": "Ann Arbor", "state": "Michigan" }, { "city": "Grand Rapids", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT03367572" }, { "nct_id": "NCT00661674", "title": "Palonosetron and Hydroxyzine to Reduce Opioid Withdrawal", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Substance-Related Disorders" ], "interventions": [ { "name": "Palonosetron", "type": "DRUG" }, { "name": "Hydroxyzine", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Stanford University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "35 Years", "sex": "MALE", "summary": "18 Years to 35 Years · Male only" }, "enrollment_count": 10, "start_date": "2008-04", "completion_date": "2008-08", "has_results": true, "last_update_posted_date": "2017-06-05", "last_synced_at": "2026-09-28T17:54:05.483Z", "location_count": 1, "location_summary": "Stanford, California", "locations": [ { "city": "Stanford", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00661674" }, { "nct_id": "NCT01395901", "title": "Safety and Efficacy of Palonosetron IV to Prevent Postoperative Nausea and Vomiting in Pediatric Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Postoperative Nausea and Vomiting" ], "interventions": [ { "name": "Palonosetron", "type": "DRUG" }, { "name": "Ondansetron", "type": "DRUG" }, { "name": "Placebo to Ondansetron", "type": "DRUG" }, { "name": "Placebo to Palonosetron", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Helsinn Healthcare SA", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "16 Years", "sex": "ALL", "summary": "Up to 16 Years" }, "enrollment_count": 670, "start_date": "2011-06", "completion_date": "2012-04", "has_results": true, "last_update_posted_date": "2014-07-30", "last_synced_at": "2026-09-28T17:54:05.483Z", "location_count": 12, "location_summary": "Florence, Alabama • Sheffield, Alabama • Washington D.C., District of Columbia + 9 more", "locations": [ { "city": "Florence", "state": "Alabama" }, { "city": "Sheffield", "state": "Alabama" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Miami", "state": "Florida" }, { "city": "Shreveport", "state": "Louisiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT01395901" }, { "nct_id": "NCT01836705", "title": "Effect of SAR302503 on ECG Activity in Patients With Solid Tumors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Neoplasm Malignant" ], "interventions": [ { "name": "SAR302503 (TG101348)", "type": "DRUG" }, { "name": "Placebo SAR302503", "type": "DRUG" }, { "name": "Panolosetron", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2013-05", "completion_date": "2014-05", "has_results": false, "last_update_posted_date": "2025-03-05", "last_synced_at": "2026-09-28T17:54:05.483Z", "location_count": 8, "location_summary": "Los Angeles, California • Augusta, Georgia • Detroit, Michigan + 4 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Augusta", "state": "Georgia" }, { "city": "Detroit", "state": "Michigan" }, { "city": "St Louis", "state": "Missouri" }, { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01836705" } ] }