{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+to+ibuprofen&page=2", "query": { "intervention": "Placebo to ibuprofen", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 113, "total_pages": 12, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+to+ibuprofen&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo+to+ibuprofen&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-04T16:44:10.723Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02837952", "title": "A Study of Ibuprofen (IBU) 250mg/APAP 500mg In The Treatment Of Post-Surgical Dental Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pain" ], "interventions": [ { "name": "FDC IBU/APAP 250 mg/500 mg", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "40 Years", "sex": "ALL", "summary": "18 Years to 40 Years" }, "enrollment_count": 123, "start_date": "2016-08-31", "completion_date": "2017-02-01", "has_results": true, "last_update_posted_date": "2018-03-05", "last_synced_at": "2026-10-04T16:44:10.723Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT02837952" }, { "nct_id": "NCT05919745", "title": "Preemptive Ibuprofen Effects on Pain Perception Following Extraction and Bone Graft", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Pain, Post Operative", "Quality of Life" ], "interventions": [ { "name": "Ibuprofen 600 mg", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Acetaminophen", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Marquette University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 50, "start_date": "2023-10-19", "completion_date": "2026-12", "has_results": false, "last_update_posted_date": "2024-09-27", "last_synced_at": "2026-10-04T16:44:10.723Z", "location_count": 1, "location_summary": "Milwaukee, Wisconsin", "locations": [ { "city": "Milwaukee", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT05919745" }, { "nct_id": "NCT00802685", "title": "Timing of PDA Closure and Respiratory Outcome in Premature Infants", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Patent Ductus Arteriosus" ], "interventions": [ { "name": "Early ibuprofen", "type": "DRUG" }, { "name": "Late ibuprofen expectant group (placebo)", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of Miami", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Day", "maximum_age": "14 Days", "sex": "ALL", "summary": "1 Day to 14 Days" }, "enrollment_count": 105, "start_date": "2007-11", "completion_date": "2011-02", "has_results": true, "last_update_posted_date": "2014-02-05", "last_synced_at": "2026-10-04T16:44:10.723Z", "location_count": 1, "location_summary": "Miami, Florida", "locations": [ { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00802685" }, { "nct_id": "NCT02272725", "title": "Non-steroidal Anti-inflammatory Affect on Kidneys in Endurance Distances", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Acute Kidney Injury", "Exercise-associated Hyponatremia", "Perceived Exertion" ], "interventions": [ { "name": "Ibuprofen", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Stanford University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 91, "start_date": "2015-03", "completion_date": "2017-01", "has_results": true, "last_update_posted_date": "2018-12-12", "last_synced_at": "2026-10-04T16:44:10.723Z", "location_count": 1, "location_summary": "Stanford, California", "locations": [ { "city": "Stanford", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02272725" }, { "nct_id": "NCT01362491", "title": "Ibuprofen Sodium Tension Headache Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pain" ], "interventions": [ { "name": "Ibuprofen Sodium", "type": "DRUG" }, { "name": "Standard Ibuprofen", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 226, "start_date": "2011-06", "completion_date": "2012-03", "has_results": true, "last_update_posted_date": "2014-07-30", "last_synced_at": "2026-10-04T16:44:10.723Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01362491" }, { "nct_id": "NCT02912650", "title": "A Safety And Efficacy Study of Ibuprofen 250 mg / Acetaminophen 500 mg In The Treatment Of Post-Surgical Dental Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Post-surgical Pain Following Extraction of Molar Teeth" ], "interventions": [ { "name": "Ibuprofen 250 mg / Acetaminophen 500 mg", "type": "DRUG" }, { "name": "Ibuprofen 250 mg", "type": "DRUG" }, { "name": "Acetaminophen 650 mg", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "40 Years", "sex": "ALL", "summary": "18 Years to 40 Years" }, "enrollment_count": 568, "start_date": "2015-09", "completion_date": "2016-06", "has_results": true, "last_update_posted_date": "2017-08-30", "last_synced_at": "2026-10-04T16:44:10.723Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT02912650" }, { "nct_id": "NCT02339129", "title": "Dosing Interval Study of SST-0225 Topical Ibuprofen Cream in the Treatment of Delayed Onset Muscle Soreness", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Delayed Onset Muscle Soreness" ], "interventions": [ { "name": "SST-0225", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Strategic Science & Technologies, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "16 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "16 Years to 65 Years" }, "enrollment_count": 72, "start_date": "2014-11", "completion_date": "2015-03", "has_results": false, "last_update_posted_date": "2016-09-09", "last_synced_at": "2026-10-04T16:44:10.723Z", "location_count": 2, "location_summary": "South Miami, Florida • Springfield, Missouri", "locations": [ { "city": "South Miami", "state": "Florida" }, { "city": "Springfield", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT02339129" }, { "nct_id": "NCT05283434", "title": "Arnica and the Management of Pain in Acute Musculoskeletal Extremity Injuries", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Pain, Muscle", "Pain, Acute" ], "interventions": [ { "name": "Arnica", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Children's Hospitals and Clinics of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "11 Years", "maximum_age": "18 Years", "sex": "ALL", "summary": "11 Years to 18 Years" }, "enrollment_count": 324, "start_date": "2021-07-15", "completion_date": "2023-06-30", "has_results": false, "last_update_posted_date": "2022-03-17", "last_synced_at": "2026-10-04T16:44:10.723Z", "location_count": 2, "location_summary": "Minneapolis, Minnesota • Saint Paul, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" }, { "city": "Saint Paul", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT05283434" }, { "nct_id": "NCT00419796", "title": "Effects of Lumiracoxib and Ibuprofen on Blood Pressure and Urinary Eicosanoid Excretion in Osteoarthritis Patients With Controlled Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Osteoarthritis With Controlled Hypertension" ], "interventions": [ { "name": "Lumiracoxib", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 78, "start_date": "2006-11", "completion_date": "2007-09", "has_results": false, "last_update_posted_date": "2007-11-29", "last_synced_at": "2026-10-04T16:44:10.723Z", "location_count": 1, "location_summary": "East Hanover, New Jersey", "locations": [ { "city": "East Hanover", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT00419796" }, { "nct_id": "NCT05494385", "title": "Effect of Perioperative Gabapentin on Postoperative Opioid Requirements", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Postoperative Pain" ], "interventions": [ { "name": "Preoperative Gabapentin/Postoperative Placebo", "type": "DRUG" }, { "name": "Preoperative Gabapentin/Postoperative Gabapentin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Indiana University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 114, "start_date": "2021-07-27", "completion_date": "2023-07-05", "has_results": true, "last_update_posted_date": "2024-10-23", "last_synced_at": "2026-10-04T16:44:10.723Z", "location_count": 1, "location_summary": "Indianapolis, Indiana", "locations": [ { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT05494385" } ] }