{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo-Apremilast&page=2", "query": { "intervention": "Placebo-Apremilast", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Placebo-Apremilast&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-27T13:58:12.040Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06586112", "title": "A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Moderate to Severe Plaque Psoriasis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Plaque Psoriasis" ], "interventions": [ { "name": "Envudeucitinib", "type": "DRUG" }, { "name": "Apremilast", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Alumis Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 912, "start_date": "2024-07-25", "completion_date": "2025-11-20", "has_results": false, "last_update_posted_date": "2026-08-10", "last_synced_at": "2026-09-27T13:58:12.040Z", "location_count": 55, "location_summary": "Phoenix, Arizona • Scottsdale, Arizona • Rogers, Arkansas + 49 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Rogers", "state": "Arkansas" }, { "city": "Chula Vista", "state": "California" }, { "city": "Encinitas", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06586112" }, { "nct_id": "NCT03747939", "title": "Efficacy, Safety, and Tolerability Study of Apremilast to Treat Early Oligoarticular Psoriatic Arthritis.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Arthritis, Psoriatic" ], "interventions": [ { "name": "Apremilast (CC-10004)", "type": "DRUG" }, { "name": "Apremilast (CC-10004) Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Amgen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 310, "start_date": "2018-12-31", "completion_date": "2023-07-05", "has_results": true, "last_update_posted_date": "2026-09-11", "last_synced_at": "2026-09-27T13:58:12.040Z", "location_count": 54, "location_summary": "Mesa, Arizona • Covina, California • Encino, California + 48 more", "locations": [ { "city": "Mesa", "state": "Arizona" }, { "city": "Covina", "state": "California" }, { "city": "Encino", "state": "California" }, { "city": "Fullerton", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03747939" }, { "nct_id": "NCT01212770", "title": "PALACE 3: Efficacy and Safety Study of Apremilast to Treat Active Psoriatic Arthritis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Psoriatic Arthritis" ], "interventions": [ { "name": "Apremilast 20mg", "type": "DRUG" }, { "name": "Apremilast 30mg", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Amgen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 505, "start_date": "2010-09-30", "completion_date": "2017-02-09", "has_results": true, "last_update_posted_date": "2020-05-06", "last_synced_at": "2026-09-27T13:58:12.040Z", "location_count": 23, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 18 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Bakersfield", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01212770" }, { "nct_id": "NCT02425826", "title": "A Phase 4 Study of Efficacy and Safety of Apremilast in Subjects With Moderate Plaque Psoriasis.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Parapsoriasis" ], "interventions": [ { "name": "Apremilast", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Placebo-Apremilast", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Amgen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 221, "start_date": "2015-04-20", "completion_date": "2016-11-22", "has_results": true, "last_update_posted_date": "2023-06-05", "last_synced_at": "2026-09-27T13:58:12.040Z", "location_count": 26, "location_summary": "Birmingham, Alabama • Fremont, California • Los Angeles, California + 21 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Fremont", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Newport Beach", "state": "California" }, { "city": "Sacramento", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02425826" }, { "nct_id": "NCT00866359", "title": "A Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in the Treatment of Behçet Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Behcet Syndrome" ], "interventions": [ { "name": "Apremilast (CC-10004)", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Amgen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 111, "start_date": "2009-08-01", "completion_date": "2012-05-01", "has_results": true, "last_update_posted_date": "2020-06-19", "last_synced_at": "2026-09-27T13:58:12.040Z", "location_count": 4, "location_summary": "Jacksonville, Florida • Boston, Massachusetts • New York, New York + 1 more", "locations": [ { "city": "Jacksonville", "state": "Florida" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "New York", "state": "New York" }, { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00866359" }, { "nct_id": "NCT07029529", "title": "Phase 2 Study of Apremilast in Women and Men With Alcohol Use Disorder", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Alcohol Use Disorder" ], "interventions": [ { "name": "Apremilast 60mg", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "21 Years to 65 Years" }, "enrollment_count": 80, "start_date": "2026-05-12", "completion_date": "2030-08", "has_results": false, "last_update_posted_date": "2026-06-08", "last_synced_at": "2026-09-27T13:58:12.040Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT07029529" }, { "nct_id": "NCT01212757", "title": "PALACE 2: Efficacy and Safety Study of Apremilast to Treat Active Psoriatic Arthritis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Psoriatic Arthritis" ], "interventions": [ { "name": "Apremilast 20mg", "type": "DRUG" }, { "name": "Apremilast 30mg", "type": "DRUG" }, { "name": "Placebo + 20 mg Apremilast", "type": "DRUG" }, { "name": "Placebo + 30 mg Apremilast", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Amgen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 488, "start_date": "2010-09-27", "completion_date": "2017-01-25", "has_results": true, "last_update_posted_date": "2020-05-06", "last_synced_at": "2026-09-27T13:58:12.040Z", "location_count": 23, "location_summary": "Tuscaloosa, Alabama • Denver, Colorado • Trumbull, Connecticut + 18 more", "locations": [ { "city": "Tuscaloosa", "state": "Alabama" }, { "city": "Denver", "state": "Colorado" }, { "city": "Trumbull", "state": "Connecticut" }, { "city": "Fort Lauderdale", "state": "Florida" }, { "city": "St. Petersburg", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01212757" }, { "nct_id": "NCT01285310", "title": "Study of Apremilast to Evaluate the Safety and Effectiveness for Patients With Rheumatoid Arthritis", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "Apremilast 30 mg", "type": "DRUG" }, { "name": "Apremilast 20 mg", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Amgen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 237, "start_date": "2010-12-09", "completion_date": "2012-09-10", "has_results": true, "last_update_posted_date": "2020-05-08", "last_synced_at": "2026-09-27T13:58:12.040Z", "location_count": 29, "location_summary": "Gilbert, Arizona • Phoenix, Arizona • La Mesa, California + 23 more", "locations": [ { "city": "Gilbert", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "La Mesa", "state": "California" }, { "city": "Palm Desert", "state": "California" }, { "city": "Palo Alto", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01285310" }, { "nct_id": "NCT06108544", "title": "A Study About How Well TAK-279 Works and Its Safety in Participants With Moderate-to-severe Plaque Psoriasis During 60 Weeks of Treatment With a Withdrawal and Retreatment Period", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Plaque Psoriasis" ], "interventions": [ { "name": "TAK-279", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Apremilast", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1108, "start_date": "2023-11-06", "completion_date": "2025-11-07", "has_results": false, "last_update_posted_date": "2025-11-20", "last_synced_at": "2026-09-27T13:58:12.040Z", "location_count": 66, "location_summary": "Birmingham, Alabama • Hoover, Alabama • Phoenix, Arizona + 54 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Hoover", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Fort Smith", "state": "Arkansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06108544" }, { "nct_id": "NCT01690299", "title": "Phase 3b Safety and Efficacy Study of Apremilast to Treat Moderate to Severe Plaque-plaque Psoriasis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Psoriasis", "Psoriatic Arthritis" ], "interventions": [ { "name": "Apremilast", "type": "DRUG" }, { "name": "Etanercept", "type": "DRUG" }, { "name": "Placebo tablet", "type": "DRUG" }, { "name": "Placebo injection", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Amgen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 250, "start_date": "2012-10-01", "completion_date": "2016-04-04", "has_results": true, "last_update_posted_date": "2022-03-15", "last_synced_at": "2026-09-27T13:58:12.040Z", "location_count": 31, "location_summary": "Phoenix, Arizona • Bakersfield, California • Irvine, California + 27 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Bakersfield", "state": "California" }, { "city": "Irvine", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Denver", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT01690299" } ] }