{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Plasma+biomarkers&page=2",
    "query": {
      "intervention": "Plasma biomarkers",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 183,
    "total_pages": 19,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Plasma+biomarkers&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Plasma+biomarkers&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-04T00:10:52.654Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00258869",
      "title": "Observational Study of Sepsis and Pneumonia to Develop Diagnostic Tests",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sepsis",
        "Septicemia",
        "Sepsis Syndrome",
        "Shock, Septic",
        "Community Acquired Pneumonia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Center for Genome Resources",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "6 Years and older"
      },
      "enrollment_count": 1200,
      "start_date": "2005-12",
      "completion_date": "2010-07",
      "has_results": false,
      "last_update_posted_date": "2010-11-09",
      "last_synced_at": "2026-10-04T00:10:52.654Z",
      "location_count": 3,
      "location_summary": "Detroit, Michigan • Durham, North Carolina",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00258869"
    },
    {
      "nct_id": "NCT02525419",
      "title": "Intermittent Fasting, Caloric Restriction and Body Composition in Obese Men and Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Weight Loss"
      ],
      "interventions": [
        {
          "name": "Weight Loss Phase",
          "type": "BEHAVIORAL"
        },
        {
          "name": "HP-IF",
          "type": "BEHAVIORAL"
        },
        {
          "name": "HH",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Skidmore College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "30 Years to 65 Years"
      },
      "enrollment_count": 43,
      "start_date": "2013-08",
      "completion_date": "2015-03",
      "has_results": false,
      "last_update_posted_date": "2015-08-24",
      "last_synced_at": "2026-10-04T00:10:52.654Z",
      "location_count": 1,
      "location_summary": "Saratoga Springs, New York",
      "locations": [
        {
          "city": "Saratoga Springs",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02525419"
    },
    {
      "nct_id": "NCT07543965",
      "title": "Cohort of Repeat Donor Experiences (CORE) Study",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Health Effects (Ferritin Levels, CRP Levels, iGg Levels, Self-reported Health)"
      ],
      "interventions": [
        {
          "name": "Plasmapheresis Procedure",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Westat",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "74 Years",
        "sex": "ALL",
        "summary": "18 Years to 74 Years"
      },
      "enrollment_count": 2090,
      "start_date": "2026-04-06",
      "completion_date": "2029-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-04-22",
      "last_synced_at": "2026-10-04T00:10:52.654Z",
      "location_count": 1,
      "location_summary": "Dallas, Georgia",
      "locations": [
        {
          "city": "Dallas",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07543965"
    },
    {
      "nct_id": "NCT03656575",
      "title": "Reduction of Pro-Inflammatory Synovial Fluid Biomarkers in Osteoarthritis of the Knee With Alpha-2 Macroglobulin",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "synovial fluid biomarker concentrations",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 75,
      "start_date": "2017-11-01",
      "completion_date": "2019-04-20",
      "has_results": false,
      "last_update_posted_date": "2020-05-29",
      "last_synced_at": "2026-10-04T00:10:52.654Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03656575"
    },
    {
      "nct_id": "NCT01495390",
      "title": "A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Amyotrophic Lateral Sclerosis",
        "Nervous System Diseases",
        "Sclerosis",
        "Motor Neuron Disease",
        "Spinal Cord Diseases",
        "Central Nervous System Diseases",
        "Neurodegenerative Diseases",
        "Neuromuscular Diseases",
        "ALS"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 139,
      "start_date": "2011-11",
      "completion_date": "2016-12-31",
      "has_results": false,
      "last_update_posted_date": "2017-05-30",
      "last_synced_at": "2026-10-04T00:10:52.654Z",
      "location_count": 6,
      "location_summary": "Phoenix, Arizona • Jacksonville, Florida • Atlanta, Georgia + 3 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Worcester",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01495390"
    },
    {
      "nct_id": "NCT04525534",
      "title": "Plasma Concentration of Biological Markers in Placenta Accreta Spectrum",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Placenta Accreta",
        "Placenta Diseases"
      ],
      "interventions": [
        {
          "name": "There is no other intervention, only clinical treatment.",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Arkansas",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 19,
      "start_date": "2020-08-30",
      "completion_date": "2023-07-10",
      "has_results": false,
      "last_update_posted_date": "2024-09-03",
      "last_synced_at": "2026-10-04T00:10:52.654Z",
      "location_count": 1,
      "location_summary": "Little Rock, Arkansas",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04525534"
    },
    {
      "nct_id": "NCT04058132",
      "title": "Cerebrovascular Reactivity Assessed With fNIRS as a Biomarker of TCVI After Acute Traumatic Brain Injury in Military",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "Sildenafil Citrate 50Mg Tab",
          "type": "DRUG"
        },
        {
          "name": "functional Near-infrared Spectroscopy (fNIRS)",
          "type": "DEVICE"
        },
        {
          "name": "Carbon Dioxide (CO2) 5%",
          "type": "OTHER"
        },
        {
          "name": "Neuropsychological Assessments",
          "type": "OTHER"
        },
        {
          "name": "Gadolinium contrast infusion",
          "type": "DRUG"
        },
        {
          "name": "Blood sample collection for research purposes",
          "type": "PROCEDURE"
        },
        {
          "name": "Structural brain Magnetic Resonance Imaging (MRI",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE",
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Uniformed Services University of the Health Sciences",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 1,
      "start_date": "2019-08-09",
      "completion_date": "2020-03-01",
      "has_results": false,
      "last_update_posted_date": "2024-02-28",
      "last_synced_at": "2026-10-04T00:10:52.654Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04058132"
    },
    {
      "nct_id": "NCT03782168",
      "title": "Plasma Concentration of Biological Markers in Placental Abruption",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Abruptio Placentae"
      ],
      "interventions": [
        {
          "name": "There is no other intervention, only clinical treatment.",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Arkansas",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 1,
      "start_date": "2019-01-31",
      "completion_date": "2021-08-01",
      "has_results": false,
      "last_update_posted_date": "2024-09-03",
      "last_synced_at": "2026-10-04T00:10:52.654Z",
      "location_count": 1,
      "location_summary": "Little Rock, Arkansas",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03782168"
    },
    {
      "nct_id": "NCT04614987",
      "title": "Serum Neurofilament Light (NfL) as a Marker for Brain Injury in Individuals Undergoing Chimeric Antigen Receptor-modified T Therapy",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neurotoxicity"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 17,
      "start_date": "2021-02-25",
      "completion_date": "2023-09-13",
      "has_results": false,
      "last_update_posted_date": "2025-05-06",
      "last_synced_at": "2026-10-04T00:10:52.654Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04614987"
    },
    {
      "nct_id": "NCT07265271",
      "title": "Project for Multi-Omics-Based Early Detection of Hepatocellular Carcinoma (PROMETHEA Study)",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hepatocellular Carcinoma (HCC)"
      ],
      "interventions": [
        {
          "name": "Small RNA sequence",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Rt-qPCR",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "City of Hope Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 600,
      "start_date": "2025-01-15",
      "completion_date": "2028-06-18",
      "has_results": false,
      "last_update_posted_date": "2026-07-01",
      "last_synced_at": "2026-10-04T00:10:52.654Z",
      "location_count": 1,
      "location_summary": "Duarte, California",
      "locations": [
        {
          "city": "Duarte",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07265271"
    }
  ]
}