{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Platelet+rich+fibrin",
    "query": {
      "intervention": "Platelet rich fibrin"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 44,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Platelet+rich+fibrin&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-19T14:45:48.445Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06776289",
      "title": "Endodontic Microsurgery",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Apical Periodontitis"
      ],
      "interventions": [
        {
          "name": "Platelet rich fibrin",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Mark Schachman",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 20,
      "start_date": "2026-10",
      "completion_date": "2027-08",
      "has_results": false,
      "last_update_posted_date": "2026-07-29",
      "last_synced_at": "2026-09-19T14:45:48.445Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06776289"
    },
    {
      "nct_id": "NCT03895476",
      "title": "To Measure Pain Perception Following De-Epithelized Free Gingival Graft Harvesting",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingival Recession",
        "Palate; Wound"
      ],
      "interventions": [
        {
          "name": "palatal wound will be cover with collagen and sutures",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "palatal wound covered with platelet rich fibrin",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "palatal wound covered with a collagen sponge and cyanoacrylate",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "palatal wound covered with a stent",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 72,
      "start_date": "2020-06-08",
      "completion_date": "2023-02-27",
      "has_results": true,
      "last_update_posted_date": "2024-08-23",
      "last_synced_at": "2026-09-19T14:45:48.445Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03895476"
    },
    {
      "nct_id": "NCT04128046",
      "title": "The Effect of Platelet-rich Fibrin Matrix on Skin Rejuvenation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Skin Rejuvenation",
        "Skin Quality",
        "Wrinkle",
        "Nasolabial Fold"
      ],
      "interventions": [
        {
          "name": "PRFM injection",
          "type": "PROCEDURE"
        },
        {
          "name": "Saline injection",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "New York Medical College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2018-09-03",
      "completion_date": "2019-06-01",
      "has_results": false,
      "last_update_posted_date": "2019-10-22",
      "last_synced_at": "2026-09-19T14:45:48.445Z",
      "location_count": 1,
      "location_summary": "Valhalla, New York",
      "locations": [
        {
          "city": "Valhalla",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04128046"
    },
    {
      "nct_id": "NCT05633511",
      "title": "Changes of Soft Tissue Grafting: A Randomized Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingival Recession"
      ],
      "interventions": [
        {
          "name": "Split Mouth Design",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Tufts University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2023-01-11",
      "completion_date": "2036-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-04-29",
      "last_synced_at": "2026-09-19T14:45:48.445Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05633511"
    },
    {
      "nct_id": "NCT03124329",
      "title": "Efficacy of Methods to Treat Multiple Gingival Recession Defects",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingival Recession"
      ],
      "interventions": [
        {
          "name": "Coronally Advanced Flap",
          "type": "PROCEDURE"
        },
        {
          "name": "Intrasulcular Tunneling",
          "type": "PROCEDURE"
        },
        {
          "name": "Vestibular Incision Subperiosteal Tunnel Access (VISTA)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Leukocyte-Platelet Rich Fibrin (L-PRF)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BIOLOGICAL",
        "DEVICE"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 0,
      "start_date": "2017-05-01",
      "completion_date": "2019-06-19",
      "has_results": false,
      "last_update_posted_date": "2025-10-15",
      "last_synced_at": "2026-09-19T14:45:48.445Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03124329"
    },
    {
      "nct_id": "NCT07023757",
      "title": "Effect of Age on PRF Quality; Assessed by Evaluating Healing Outcomes of ARP",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healing Wound"
      ],
      "interventions": [
        {
          "name": "Socket preservation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "20 Years to 80 Years"
      },
      "enrollment_count": 44,
      "start_date": "2025-06-12",
      "completion_date": "2027-07-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-15",
      "last_synced_at": "2026-09-19T14:45:48.445Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07023757"
    },
    {
      "nct_id": "NCT07359131",
      "title": "Postoperative Assessment of Platelet-Rich Plasma and Platelet-Rich Fibrin in Temporomandibular Joint Surgery",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Temporomandibular Joint Disorders"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Jingping Wang, MD, Ph.D.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 700,
      "start_date": "2026-11-15",
      "completion_date": "2027-12-05",
      "has_results": false,
      "last_update_posted_date": "2026-06-09",
      "last_synced_at": "2026-09-19T14:45:48.445Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07359131"
    },
    {
      "nct_id": "NCT02477358",
      "title": "The Use of Platelet Rich Fibrin in Pulpal and Periodontal Regeneration in Mature Teeth",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pulpal Necrosis"
      ],
      "interventions": [
        {
          "name": "Left Tooth Platelet Rich Fibrin; Right Tooth Implant Alone",
          "type": "PROCEDURE"
        },
        {
          "name": "Right Tooth Platelet Rich Fibrin; Left Tooth Implant Alone",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2014-09-29",
      "completion_date": "2016-06-01",
      "has_results": true,
      "last_update_posted_date": "2023-10-04",
      "last_synced_at": "2026-09-19T14:45:48.445Z",
      "location_count": 1,
      "location_summary": "Lincoln, Nebraska",
      "locations": [
        {
          "city": "Lincoln",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02477358"
    },
    {
      "nct_id": "NCT03805698",
      "title": "Use of Platelet Rich Plasma After Arthroscopic Debridement for Triangular Fibrocartilage Complex Tears",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthroscopic Surgery",
        "Triangular Fibrocartilage Complex Injury"
      ],
      "interventions": [
        {
          "name": "Platelet-rich Plasma (PRP)",
          "type": "DEVICE"
        },
        {
          "name": "Standard Arthroscopic Debridement",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2019-01-03",
      "completion_date": "2021-02-06",
      "has_results": true,
      "last_update_posted_date": "2022-10-06",
      "last_synced_at": "2026-09-19T14:45:48.445Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03805698"
    },
    {
      "nct_id": "NCT04964466",
      "title": "Release Kinetics in PRF Versus GEM21S With and Without Bone Substitutes: An In Vitro Analysis",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bone Loss"
      ],
      "interventions": [
        {
          "name": "Amount of PDGF-BB in PRF preparation vs. GEM21",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Amount of PDGF-BB available in PRF + bone substitutes vs. rhPDGF-BB+ bone substitutes following preparation",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Release kinetics of PDGF-BB in PRF + bone substitutes vs. rhPDGF-BB + bone substitutes",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Release kinetics of PDGF-BB in rhPDGF-BB + PRF + bone substitutes",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 5,
      "start_date": "2021-08-31",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-12-02",
      "last_synced_at": "2026-09-19T14:45:48.445Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04964466"
    }
  ]
}