{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Poractant+alfa",
    "query": {
      "intervention": "Poractant alfa"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 15,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Poractant+alfa&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-07T11:30:56.103Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04209946",
      "title": "Early Caffeine and LISA Compared to Caffeine and CPAP in Preterm Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premature Lungs",
        "Respiratory Distress Syndrome",
        "Surfactant Deficiency Syndrome Neonatal"
      ],
      "interventions": [
        {
          "name": "Less Invasive Surfactant Administration LISA",
          "type": "PROCEDURE"
        },
        {
          "name": "Continuous Positive Airway Pressure CPAP",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Sharp HealthCare",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "24 Weeks",
        "maximum_age": "29 Weeks",
        "sex": "ALL",
        "summary": "24 Weeks to 29 Weeks"
      },
      "enrollment_count": 180,
      "start_date": "2020-01-22",
      "completion_date": "2025-11-10",
      "has_results": false,
      "last_update_posted_date": "2025-12-18",
      "last_synced_at": "2026-09-07T11:30:56.103Z",
      "location_count": 3,
      "location_summary": "Irvine, California • Loma Linda, California • San Diego, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04209946"
    },
    {
      "nct_id": "NCT04545866",
      "title": "The Budesonide in Babies (BiB) Trial",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Bronchopulmonary Dysplasia (BPD)",
        "Respiratory Distress Syndrome",
        "Prematurity; Extreme",
        "Neonatal"
      ],
      "interventions": [
        {
          "name": "budesonide (Pulmicort nebulizing suspension).",
          "type": "DRUG"
        },
        {
          "name": "surfactant (poractant alfa;Curosurf)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "48 Hours",
        "sex": "ALL",
        "summary": "Up to 48 Hours"
      },
      "enrollment_count": 642,
      "start_date": "2021-04-01",
      "completion_date": "2026-12-17",
      "has_results": true,
      "last_update_posted_date": "2026-04-15",
      "last_synced_at": "2026-09-07T11:30:56.103Z",
      "location_count": 19,
      "location_summary": "Birmingham, Alabama • Palo Alto, California • San Diego, California + 15 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04545866"
    },
    {
      "nct_id": "NCT04502433",
      "title": "Poractant Alfa (Curosurf®)) -- Effect in Adult Patients Diagnosed With 2019 Novel Coronavirus (SARS-COV-19; (Covid-19)) Acute Respiratory Distress Syndrome (ARDS)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "CUROSURF® (poractant alfa)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Chiesi Farmaceutici S.p.A.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 22,
      "start_date": "2021-01-06",
      "completion_date": "2022-03-17",
      "has_results": true,
      "last_update_posted_date": "2023-06-23",
      "last_synced_at": "2026-09-07T11:30:56.103Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04502433"
    },
    {
      "nct_id": "NCT02834624",
      "title": "Comparison of Curosurf and Infasurf in the Treatment of Preterm Infants With Respiratory Distress Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "Poractant alfa",
          "type": "DRUG"
        },
        {
          "name": "calfactant",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Weeks",
        "maximum_age": "35 Weeks",
        "sex": "ALL",
        "summary": "22 Weeks to 35 Weeks"
      },
      "enrollment_count": 30,
      "start_date": "2013-07",
      "completion_date": "2015-07",
      "has_results": true,
      "last_update_posted_date": "2017-06-06",
      "last_synced_at": "2026-09-07T11:30:56.103Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02834624"
    },
    {
      "nct_id": "NCT04181255",
      "title": "Cold Heart Study: A Randomized Pilot Trial of Surfactant Therapy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Congenital Heart Disease",
        "Hypoplastic Left Heart Syndrome"
      ],
      "interventions": [
        {
          "name": "Curosurf",
          "type": "DRUG"
        },
        {
          "name": "Sham",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "12 Weeks",
        "sex": "ALL",
        "summary": "1 Day to 12 Weeks"
      },
      "enrollment_count": 2,
      "start_date": "2020-02-25",
      "completion_date": "2020-06-12",
      "has_results": false,
      "last_update_posted_date": "2023-09-13",
      "last_synced_at": "2026-09-07T11:30:56.103Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04181255"
    },
    {
      "nct_id": "NCT02140580",
      "title": "OPTIMIST-A Trial: Minimally-invasive Surfactant Therapy in Preterm Infants 25-28 Weeks Gestation on CPAP",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Bronchopulmonary Dysplasia"
      ],
      "interventions": [
        {
          "name": "Minimally invasive surfactant therapy",
          "type": "DEVICE"
        },
        {
          "name": "Continuation on CPAP",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Menzies Institute for Medical Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Minute",
        "maximum_age": "6 Hours",
        "sex": "ALL",
        "summary": "1 Minute to 6 Hours"
      },
      "enrollment_count": 486,
      "start_date": "2011-12",
      "completion_date": "2022-06",
      "has_results": false,
      "last_update_posted_date": "2020-05-01",
      "last_synced_at": "2026-09-07T11:30:56.103Z",
      "location_count": 5,
      "location_summary": "New Haven, Connecticut • Honolulu, Hawaii • Evanston, Illinois + 2 more",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Honolulu",
          "state": "Hawaii"
        },
        {
          "city": "Evanston",
          "state": "Illinois"
        },
        {
          "city": "Camden",
          "state": "New Jersey"
        },
        {
          "city": "Morgantown",
          "state": "West Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02140580"
    },
    {
      "nct_id": "NCT02452476",
      "title": "A Double Blind, Randomized, Controlled Study to Evaluate CHF 5633 (Synthetic Surfactant) and Poractant Alfa in Neonates With Respiratory Distress Syndrome (RDS) (POC)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Respiratory Distress Syndrome, Newborn"
      ],
      "interventions": [
        {
          "name": "CHF5633",
          "type": "DRUG"
        },
        {
          "name": "Poractant alfa",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Chiesi Farmaceutici S.p.A.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Hour",
        "maximum_age": "24 Hours",
        "sex": "ALL",
        "summary": "1 Hour to 24 Hours"
      },
      "enrollment_count": 123,
      "start_date": "2016-01-21",
      "completion_date": "2018-05-24",
      "has_results": true,
      "last_update_posted_date": "2021-08-13",
      "last_synced_at": "2026-09-07T11:30:56.103Z",
      "location_count": 23,
      "location_summary": "Mobile, Alabama • Los Angeles, California • Orange, California + 20 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02452476"
    },
    {
      "nct_id": "NCT01537354",
      "title": "Comparison in Pulmonary Compliance Between Curosurf and Survanta in Preterm Infants With Respiratory Distress Syndrome",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "Curosurf®",
          "type": "DRUG"
        },
        {
          "name": "Survanta®",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Minutes",
        "maximum_age": "12 Hours",
        "sex": "ALL",
        "summary": "15 Minutes to 12 Hours"
      },
      "enrollment_count": 0,
      "start_date": "2012-06",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2014-01-08",
      "last_synced_at": "2026-09-07T11:30:56.103Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01537354"
    },
    {
      "nct_id": "NCT00767039",
      "title": "Curosurf and Survanta Treatment(CAST)of RDS in Very Premature Infants",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Prematurity",
        "Respiratory Distress Syndrome",
        "Patent Ductus Arteriosus"
      ],
      "interventions": [
        {
          "name": "Survanta (beractant)",
          "type": "DRUG"
        },
        {
          "name": "Curosurf (poractant)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alan Fujii",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "8 Hours",
        "sex": "ALL",
        "summary": "Up to 8 Hours"
      },
      "enrollment_count": 52,
      "start_date": "2005-01",
      "completion_date": "2009-01",
      "has_results": true,
      "last_update_posted_date": "2011-10-03",
      "last_synced_at": "2026-09-07T11:30:56.103Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00767039"
    },
    {
      "nct_id": "NCT04715373",
      "title": "LISA in the Delivery Room for Extremely Preterm Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Extreme Prematurity",
        "Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "LISA",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Minutes",
        "maximum_age": "20 Minutes",
        "sex": "ALL",
        "summary": "5 Minutes to 20 Minutes"
      },
      "enrollment_count": 60,
      "start_date": "2021-06-22",
      "completion_date": "2025-04-08",
      "has_results": false,
      "last_update_posted_date": "2026-01-08",
      "last_synced_at": "2026-09-07T11:30:56.103Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04715373"
    }
  ]
}