{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Positive+Airway+Pressure+%28PAP%29",
    "query": {
      "intervention": "Positive Airway Pressure (PAP)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 81,
    "total_pages": 9,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Positive+Airway+Pressure+%28PAP%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-29T10:40:18.005Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01807897",
      "title": "Oxygen Versus PAP for Sleep Apnea in Heart Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Heart Failure",
        "Sleep Apnea Syndromes"
      ],
      "interventions": [
        {
          "name": "Continuous positive airway pressure",
          "type": "DEVICE"
        },
        {
          "name": "Nocturnal supplemental oxygen",
          "type": "DEVICE"
        },
        {
          "name": "Healthy Lifestyle and Sleep Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 74,
      "start_date": "2014-06-23",
      "completion_date": "2020-06-30",
      "has_results": true,
      "last_update_posted_date": "2023-01-25",
      "last_synced_at": "2026-09-29T10:40:18.005Z",
      "location_count": 2,
      "location_summary": "West Haven, Connecticut • Boston, Massachusetts",
      "locations": [
        {
          "city": "West Haven",
          "state": "Connecticut"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01807897"
    },
    {
      "nct_id": "NCT07226765",
      "title": "Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Obstructive Sleep Apnea"
      ],
      "interventions": [
        {
          "name": "Maridebart cafraglutide",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Amgen",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 250,
      "start_date": "2025-11-25",
      "completion_date": "2028-09-13",
      "has_results": false,
      "last_update_posted_date": "2026-08-14",
      "last_synced_at": "2026-09-29T10:40:18.005Z",
      "location_count": 13,
      "location_summary": "Northridge, California • Rolling Hills Estates, California • Brandon, Florida + 10 more",
      "locations": [
        {
          "city": "Northridge",
          "state": "California"
        },
        {
          "city": "Rolling Hills Estates",
          "state": "California"
        },
        {
          "city": "Brandon",
          "state": "Florida"
        },
        {
          "city": "Palmetto Bay",
          "state": "Florida"
        },
        {
          "city": "Pompano Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07226765"
    },
    {
      "nct_id": "NCT04306211",
      "title": "Comparison of Oxygenation Between Nasal PAP vs Nasal During Propofol-based Sedation for EUS",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Endoscopic Ultrasound"
      ],
      "interventions": [
        {
          "name": "SuperNO2VA",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 11,
      "start_date": "2020-12-14",
      "completion_date": "2022-03-30",
      "has_results": true,
      "last_update_posted_date": "2022-11-03",
      "last_synced_at": "2026-09-29T10:40:18.005Z",
      "location_count": 2,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04306211"
    },
    {
      "nct_id": "NCT04179981",
      "title": "Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep Apnea Syndrome",
        "Obstructive Sleep Apnea",
        "COPD",
        "Overlap Syndrome",
        "Quality of Life",
        "Neurocognitive Function",
        "Sleepiness",
        "Elderly",
        "Positive Airway Pressure"
      ],
      "interventions": [
        {
          "name": "Positive airway pressure",
          "type": "DEVICE"
        },
        {
          "name": "Conservative care (control arm)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 668,
      "start_date": "2020-12-01",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-05",
      "last_synced_at": "2026-09-29T10:40:18.005Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04179981"
    },
    {
      "nct_id": "NCT05094271",
      "title": "Is Obstructive Sleep Apnea Important in the Development of Alzheimer's Disease?",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "OSA",
        "Sleep Apnea",
        "Obstructive Sleep Apnea",
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "Supplemental Oxygen",
          "type": "OTHER"
        },
        {
          "name": "Continuous Positive Airway Pressure Machine",
          "type": "DEVICE"
        },
        {
          "name": "Room Air",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "65 Years to 85 Years"
      },
      "enrollment_count": 182,
      "start_date": "2021-10-08",
      "completion_date": "2025-06-12",
      "has_results": true,
      "last_update_posted_date": "2026-05-11",
      "last_synced_at": "2026-09-29T10:40:18.005Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05094271"
    },
    {
      "nct_id": "NCT04928157",
      "title": "Prospective Randomized Trial of CPAP for SDB in Patients Who Use Opioids",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Sleep Disorder; Breathing-Related",
        "Pain",
        "Sleep Apnea",
        "Obstructive Sleep Apnea",
        "Sleep",
        "Sleep Disorder",
        "Chronic Pain",
        "Opioid Use"
      ],
      "interventions": [
        {
          "name": "Positive Airway Pressure (PAP)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 62,
      "start_date": "2021-08-10",
      "completion_date": "2024-09-12",
      "has_results": false,
      "last_update_posted_date": "2024-12-02",
      "last_synced_at": "2026-09-29T10:40:18.005Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04928157"
    },
    {
      "nct_id": "NCT04132999",
      "title": "Positive Airway Pressure (PAP) for Children With Down Syndrome (DS) and Obstructive Sleep Apnea Syndrome (OSAS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Down Syndrome",
        "Obstructive Sleep Apnea"
      ],
      "interventions": [
        {
          "name": "Family-informed intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Clinical Care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "6 Years to 18 Years"
      },
      "enrollment_count": 27,
      "start_date": "2021-03-01",
      "completion_date": "2025-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-30",
      "last_synced_at": "2026-09-29T10:40:18.005Z",
      "location_count": 3,
      "location_summary": "Miami, Florida • Cincinnati, Ohio • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04132999"
    },
    {
      "nct_id": "NCT04029311",
      "title": "Comparison of Two Techniques of Combination Therapy for Treatment of Obstructive Sleep Apnea (OSA)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Treatment for Obstructive Sleep Apnea"
      ],
      "interventions": [
        {
          "name": "Nuance Pro",
          "type": "DEVICE"
        },
        {
          "name": "autoPAP",
          "type": "DEVICE"
        },
        {
          "name": "TAP PAP",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Joseph Adame",
      "sponsor_class": "INDIV",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 28,
      "start_date": "2017-06-08",
      "completion_date": "2019-05-07",
      "has_results": true,
      "last_update_posted_date": "2021-04-02",
      "last_synced_at": "2026-09-29T10:40:18.005Z",
      "location_count": 1,
      "location_summary": "Edinburg, Texas",
      "locations": [
        {
          "city": "Edinburg",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04029311"
    },
    {
      "nct_id": "NCT02507297",
      "title": "Sleep-Disordered Breathing and PAP in Perinatal Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep-disordered Breathing",
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "Positive Airway Pressure (PAP)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 29,
      "start_date": "2016-01",
      "completion_date": "2020-04-25",
      "has_results": true,
      "last_update_posted_date": "2023-05-01",
      "last_synced_at": "2026-09-29T10:40:18.005Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02507297"
    },
    {
      "nct_id": "NCT01403194",
      "title": "Continuous Positive Airway Pressure and Cardiometabolic Risk",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep Disordered Breathing"
      ],
      "interventions": [
        {
          "name": "CPAP/BiPAP",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "8 Years to 18 Years"
      },
      "enrollment_count": 11,
      "start_date": "2011-03",
      "completion_date": "2013-01",
      "has_results": true,
      "last_update_posted_date": "2014-05-13",
      "last_synced_at": "2026-09-29T10:40:18.005Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01403194"
    }
  ]
}