{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Positive+Control-Sodium+lauryl+sulfate+%28SLS%29",
    "query": {
      "intervention": "Positive Control-Sodium lauryl sulfate (SLS)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 12,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Positive+Control-Sodium+lauryl+sulfate+%28SLS%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-28T10:48:23.768Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04531813",
      "title": "Study to Determine Skin Irritation Potential of an Antifungal Cream Containing Trolamine After Repeated Skin Application (Cumulative Irritation Patch Test)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Hypersensitivity"
      ],
      "interventions": [
        {
          "name": "Butenafine HCl 1% (BAY1896425)",
          "type": "DRUG"
        },
        {
          "name": "Positive Control-Sodium lauryl sulfate (SLS)",
          "type": "DRUG"
        },
        {
          "name": "Negative Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Bayer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 32,
      "start_date": "2013-06-10",
      "completion_date": "2013-07-01",
      "has_results": true,
      "last_update_posted_date": "2020-09-25",
      "last_synced_at": "2026-09-28T10:48:23.768Z",
      "location_count": 1,
      "location_summary": "Fairfield, New Jersey",
      "locations": [
        {
          "city": "Fairfield",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04531813"
    },
    {
      "nct_id": "NCT05260359",
      "title": "Dermal Irritation, Sensitization and Cumulative Irritation Potential of 6% Bemotrizinol",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Sunburn"
      ],
      "interventions": [
        {
          "name": "6% Bemotrizinol (BEMT) in a basic sunscreen oil formulation",
          "type": "DRUG"
        },
        {
          "name": "6% Bemotrizinol (BEMT) dispersion in petrolatum",
          "type": "DRUG"
        },
        {
          "name": "Sunscreen oil vehicle with 10% ethanol as penetration enhancer without BEMT",
          "type": "OTHER"
        },
        {
          "name": "Petrolatum vehicle",
          "type": "OTHER"
        },
        {
          "name": "0.9% Saline",
          "type": "OTHER"
        },
        {
          "name": "Sodium Lauryl Sulfate 0.1% (SLS)",
          "type": "OTHER"
        },
        {
          "name": "Undosed patch",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "dsm-firmenich Switzerland AG",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 224,
      "start_date": "2022-02-23",
      "completion_date": "2022-04-08",
      "has_results": false,
      "last_update_posted_date": "2022-08-26",
      "last_synced_at": "2026-09-28T10:48:23.768Z",
      "location_count": 1,
      "location_summary": "Piscataway, New Jersey",
      "locations": [
        {
          "city": "Piscataway",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05260359"
    },
    {
      "nct_id": "NCT01821274",
      "title": "A 21-Day Topical Safety Study of Diltiazem Hydrochloride Using a Cumulative Irritant Patch Test Design",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Skin Irritation"
      ],
      "interventions": [
        {
          "name": "Diltiazem Hydrochloride 2% Cream",
          "type": "DRUG"
        },
        {
          "name": "Vehicle Cream",
          "type": "DRUG"
        },
        {
          "name": "0.1% solution o sodium lauryl sulfate (SLS)",
          "type": "DRUG"
        },
        {
          "name": "Saline 0.9%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ventrus Biosciences, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 30,
      "start_date": "2013-03",
      "completion_date": "2013-09",
      "has_results": false,
      "last_update_posted_date": "2013-08-21",
      "last_synced_at": "2026-09-28T10:48:23.768Z",
      "location_count": 1,
      "location_summary": "Paramus, New Jersey",
      "locations": [
        {
          "city": "Paramus",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01821274"
    },
    {
      "nct_id": "NCT03502434",
      "title": "A Repeat Insult Patch Test (RIPT) Study Evaluating the Sensitization Potential of Topical SM04755 Solution in Healthy Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Tendinopathy"
      ],
      "interventions": [
        {
          "name": "SM04755",
          "type": "DRUG"
        },
        {
          "name": "Vehicle",
          "type": "OTHER"
        },
        {
          "name": "White Petrolatum",
          "type": "OTHER"
        },
        {
          "name": "Sodium lauryl sulfate",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Biosplice Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 223,
      "start_date": "2017-09-11",
      "completion_date": "2017-11-17",
      "has_results": false,
      "last_update_posted_date": "2018-04-18",
      "last_synced_at": "2026-09-28T10:48:23.768Z",
      "location_count": 1,
      "location_summary": "Lynchburg, Virginia",
      "locations": [
        {
          "city": "Lynchburg",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03502434"
    },
    {
      "nct_id": "NCT02198963",
      "title": "21 Day Cumulative Skin Irritation of RUT058-60",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Irritation/Irritant"
      ],
      "interventions": [
        {
          "name": "Hypochlorous acid solution 106 mg/L",
          "type": "DRUG"
        },
        {
          "name": "0.1% (w/v) Sodium Lauryl Sulfate",
          "type": "DRUG"
        },
        {
          "name": "0.9% Physiological Saline, USP",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pulmatrix Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 43,
      "start_date": "2014-07",
      "completion_date": "2014-09",
      "has_results": true,
      "last_update_posted_date": "2016-02-04",
      "last_synced_at": "2026-09-28T10:48:23.768Z",
      "location_count": 1,
      "location_summary": "Butte, Montana",
      "locations": [
        {
          "city": "Butte",
          "state": "Montana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02198963"
    },
    {
      "nct_id": "NCT04882631",
      "title": "A Study to Evaluate the Skin Irritation Potential of PBI-100 Topical Cream in Healthy Participants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "PBI-100 Topical Cream",
          "type": "DRUG"
        },
        {
          "name": "Positive Control - Sodium laurel sulfate (SLS)",
          "type": "DRUG"
        },
        {
          "name": "PBI-100 Topical Cream, Vehicle",
          "type": "OTHER"
        },
        {
          "name": "Negative Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Pyramid Biosciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 30,
      "start_date": "2021-04-12",
      "completion_date": "2021-05-03",
      "has_results": false,
      "last_update_posted_date": "2022-01-27",
      "last_synced_at": "2026-09-28T10:48:23.768Z",
      "location_count": 1,
      "location_summary": "Newtown Square, Pennsylvania",
      "locations": [
        {
          "city": "Newtown Square",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04882631"
    },
    {
      "nct_id": "NCT02224625",
      "title": "Irritation and Sensitization of Chlorhexidine Gluconate (CHG) Cloth",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Surgery"
      ],
      "interventions": [
        {
          "name": "2% CHG Cloth solution",
          "type": "DRUG"
        },
        {
          "name": "Vehicle Cloth",
          "type": "DEVICE"
        },
        {
          "name": "Active Comparator",
          "type": "DRUG"
        },
        {
          "name": "Saline",
          "type": "OTHER"
        },
        {
          "name": "SLS",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Medline Industries",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 249,
      "start_date": "2014-08",
      "completion_date": "2015-06",
      "has_results": true,
      "last_update_posted_date": "2017-03-09",
      "last_synced_at": "2026-09-28T10:48:23.768Z",
      "location_count": 1,
      "location_summary": "Butte, Montana",
      "locations": [
        {
          "city": "Butte",
          "state": "Montana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02224625"
    },
    {
      "nct_id": "NCT01816529",
      "title": "Topical Safety Study of Topical Diltiazem Hydrochloride",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Diltiazem Skin Sensitivity."
      ],
      "interventions": [
        {
          "name": "Diltiazem Hydrochloride 2% Cream",
          "type": "DRUG"
        },
        {
          "name": "Vehicle Cream",
          "type": "DRUG"
        },
        {
          "name": "0.1% solution of sodium lauryl sulfate (SLS)",
          "type": "DRUG"
        },
        {
          "name": "Saline (0.9%)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ventrus Biosciences, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2013-03",
      "completion_date": "2013-09",
      "has_results": false,
      "last_update_posted_date": "2013-08-21",
      "last_synced_at": "2026-09-28T10:48:23.768Z",
      "location_count": 1,
      "location_summary": "Paramus, New Jersey",
      "locations": [
        {
          "city": "Paramus",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01816529"
    },
    {
      "nct_id": "NCT02168478",
      "title": "Neo-Synalar Modified 48 Hour Patch Test",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Allergy"
      ],
      "interventions": [
        {
          "name": "Neo-Synalar Cream",
          "type": "DRUG"
        },
        {
          "name": "Sodium Lauryl Sulfate Aqueous Solution (0.40%)",
          "type": "OTHER"
        },
        {
          "name": "Saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Noah Rosenberg, MD",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 206,
      "start_date": "2014-06",
      "completion_date": "2014-06",
      "has_results": true,
      "last_update_posted_date": "2015-12-11",
      "last_synced_at": "2026-09-28T10:48:23.768Z",
      "location_count": 1,
      "location_summary": "Fairfield, New Jersey",
      "locations": [
        {
          "city": "Fairfield",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02168478"
    },
    {
      "nct_id": "NCT04942496",
      "title": "A 96-hour Patch Test Study Using Healthy Human Volunteers to Assess the Skin Irritation Potential of 11 Topically Applied Formulations",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Skin Irritancy Potential"
      ],
      "interventions": [
        {
          "name": "Chlorhexidine Gluconate",
          "type": "DRUG"
        },
        {
          "name": "Hibi Universal Bathing System",
          "type": "DEVICE"
        },
        {
          "name": "0.1% SLS",
          "type": "OTHER"
        },
        {
          "name": "Distilled Water",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Molnlycke Health Care AB",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 44,
      "start_date": "2021-06",
      "completion_date": "2021-07",
      "has_results": false,
      "last_update_posted_date": "2021-06-28",
      "last_synced_at": "2026-09-28T10:48:23.768Z",
      "location_count": 1,
      "location_summary": "Bozeman, Montana",
      "locations": [
        {
          "city": "Bozeman",
          "state": "Montana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04942496"
    }
  ]
}