{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Positive+or+negative+pressure", "query": { "intervention": "Positive or negative pressure" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 13, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Positive+or+negative+pressure&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-24T05:25:56.801Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05764564", "title": "External Body Pressure in Heart Failure With Preserved Ejection Fraction", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Heart Failure, Diastolic" ], "interventions": [ { "name": "Positive or negative pressure", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "30 Years", "maximum_age": null, "sex": "ALL", "summary": "30 Years and older" }, "enrollment_count": 27, "start_date": "2023-04-21", "completion_date": "2025-05-31", "has_results": true, "last_update_posted_date": "2026-09-11", "last_synced_at": "2026-09-24T05:25:56.801Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT05764564" }, { "nct_id": "NCT03005977", "title": "Identifying Stress Urinary Incontinence in Women With Pelvic Organ Prolapse", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Stress Urinary Incontinence", "Pelvic Organ Prolapse" ], "interventions": [ { "name": "Urodynamics", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "The Cleveland Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 100, "start_date": "2017-02-15", "completion_date": "2021-12-31", "has_results": false, "last_update_posted_date": "2022-04-07", "last_synced_at": "2026-09-24T05:25:56.801Z", "location_count": 1, "location_summary": "Weston, Florida", "locations": [ { "city": "Weston", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03005977" }, { "nct_id": "NCT05535738", "title": "Using a Contact Dermatitis Model With Biologic Medications to Study Skin Inflammation", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Skin Inflammation", "Allergic Contact Dermatitis" ], "interventions": [ { "name": "Squaric Acid Dibutyl Ester", "type": "DRUG" }, { "name": "Known patch test allergens", "type": "OTHER" }, { "name": "Dupilumab", "type": "DRUG" }, { "name": "Adalimumab", "type": "DRUG" }, { "name": "Ustekinumab", "type": "DRUG" }, { "name": "Guselkumab", "type": "DRUG" }, { "name": "Canakinumab", "type": "DRUG" }, { "name": "Sarilumab", "type": "DRUG" }, { "name": "Triamcinolone Acetonide", "type": "DRUG" }, { "name": "Betamethasone Valerate", "type": "DRUG" }, { "name": "Fluticasone Propionate", "type": "DRUG" }, { "name": "Microneedle", "type": "DEVICE" }, { "name": "Suction blistering", "type": "DEVICE" }, { "name": "Skin punch biopsy", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "OTHER", "DEVICE", "PROCEDURE" ], "sponsor": "Wei-Che Ko", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 45, "start_date": "2022-11-15", "completion_date": "2027-12-31", "has_results": false, "last_update_posted_date": "2026-06-09", "last_synced_at": "2026-09-24T05:25:56.801Z", "location_count": 1, "location_summary": "Worcester, Massachusetts", "locations": [ { "city": "Worcester", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT05535738" }, { "nct_id": "NCT01824576", "title": "Effect of Intrathoracic Pressure Regulation on Decreased Cerebral Perfusion", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Head Injury", "Intracranial Pathology", "Compromised Cerebral Perfusion" ], "interventions": [ { "name": "ITPR", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Advanced Circulatory Systems", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 9, "start_date": "2013-04", "completion_date": "2016-11", "has_results": true, "last_update_posted_date": "2017-09-27", "last_synced_at": "2026-09-24T05:25:56.801Z", "location_count": 2, "location_summary": "Denver, Colorado • Baltimore, Maryland", "locations": [ { "city": "Denver", "state": "Colorado" }, { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT01824576" }, { "nct_id": "NCT03200548", "title": "Acupressure for Fatigue in Systemic Lupus Erythematosus", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Fatigue", "Lupus Erythematosus, Systemic", "Pain, Chronic", "Quality of Life", "Sleep" ], "interventions": [ { "name": "Relaxing acupressure plus usual care", "type": "BEHAVIORAL" }, { "name": "Usual care", "type": "BEHAVIORAL" }, { "name": "Stimulating acupressure plus usual care", "type": "BEHAVIORAL" }, { "name": "Sham acupressure plus usual care", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Suzanna Zick", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 52, "start_date": "2017-08-14", "completion_date": "2019-07-19", "has_results": true, "last_update_posted_date": "2023-05-12", "last_synced_at": "2026-09-24T05:25:56.801Z", "location_count": 1, "location_summary": "Ann Arbor, Michigan", "locations": [ { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT03200548" }, { "nct_id": "NCT03183063", "title": "Non-Contrast 4DCT to Detect Pulmonary Thromboembolic Events", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Pulmonary Thromboembolisms", "Pulmonary Embolism" ], "interventions": [ { "name": "4DCT and SPECT/CT", "type": "DEVICE" }, { "name": "4DCT with BiPAP and SPECT/CT", "type": "DEVICE" }, { "name": "4DCT with CTA in suspected PE", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Thomas Guerrero", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 139, "start_date": "2017-04-12", "completion_date": "2019-04-24", "has_results": true, "last_update_posted_date": "2020-06-05", "last_synced_at": "2026-09-24T05:25:56.801Z", "location_count": 1, "location_summary": "Royal Oak, Michigan", "locations": [ { "city": "Royal Oak", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT03183063" }, { "nct_id": "NCT00577772", "title": "Transit Time and Bacterial Overgrowth Using SmartPill Capsule", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Small Bowel Bacterial Overgrowth", "Gastrointestinal Diseases", "Stomach Diseases", "Digestive System Diseases" ], "interventions": [ { "name": "Xifaxan", "type": "DRUG" }, { "name": "SmartPill", "type": "DEVICE" }, { "name": "Lactulose hydrogen breath test (H_2BT)", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "DEVICE", "PROCEDURE" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 17, "start_date": "2007-11", "completion_date": "2010-07", "has_results": true, "last_update_posted_date": "2012-10-05", "last_synced_at": "2026-09-24T05:25:56.801Z", "location_count": 1, "location_summary": "Scottsdale, Arizona", "locations": [ { "city": "Scottsdale", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00577772" }, { "nct_id": "NCT07400718", "title": "Head-to-Head Comparison Study Between Different FDA Registered Allergy Skin Test Applicators", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Allergy", "Hypersensitivity, Immediate", "Ig-E Mediated Food" ], "interventions": [ { "name": "AllerTest-10 Multi-Head Skin Test Device", "type": "DEVICE" }, { "name": "Skintestor OMNI Multi-Head Skin Test Device", "type": "DEVICE" }, { "name": "Multi-Test II Multi-Head Skin Test Device", "type": "DEVICE" }, { "name": "AllerTest-8 Multi-Head Skin Test Device", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "QHSLab, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 30, "start_date": "2025-11-12", "completion_date": "2026-01-30", "has_results": false, "last_update_posted_date": "2026-02-12", "last_synced_at": "2026-09-24T05:25:56.801Z", "location_count": 1, "location_summary": "Miami, Florida", "locations": [ { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07400718" }, { "nct_id": "NCT02388880", "title": "Effect of Intrathoracic Pressure Regulation on Decreased Cerebral Perfusion (4hour)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Head Injury", "Intracranial Pathology", "Compromised Cerebral Perfusion" ], "interventions": [ { "name": "ITPR", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Advanced Circulatory Systems", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 3, "start_date": "2015-02", "completion_date": "2016-11", "has_results": true, "last_update_posted_date": "2019-04-22", "last_synced_at": "2026-09-24T05:25:56.801Z", "location_count": 1, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02388880" }, { "nct_id": "NCT01974726", "title": "Gas Supply, Demand and Middle Ear Gas Balance -- Diagnosis of Eustachian Tube Dysfunction", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Eustachian Tube Dysfunction" ], "interventions": [ { "name": "ET Stress test", "type": "OTHER" }, { "name": "Sonotubometry", "type": "OTHER" }, { "name": "Forced Response Test (FRT)", "type": "OTHER" }, { "name": "Inflation Deflation Test (IDT)", "type": "OTHER" }, { "name": "Maneuver Sequence", "type": "OTHER" }, { "name": "9-Step Test", "type": "OTHER" }, { "name": "Tubomanometry", "type": "OTHER" }, { "name": "Videoendoscopic assessment of ETF", "type": "OTHER" }, { "name": "Pressure chamber ET test", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Pittsburgh", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "3 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "3 Years to 70 Years" }, "enrollment_count": 95, "start_date": "2013-10", "completion_date": "2019-06-27", "has_results": false, "last_update_posted_date": "2020-10-08", "last_synced_at": "2026-09-24T05:25:56.801Z", "location_count": 1, "location_summary": "Pittsburgh, Pennsylvania", "locations": [ { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01974726" } ] }