{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PrEP+for+participants+without+HIV",
    "query": {
      "intervention": "PrEP for participants without HIV"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-27T07:18:36.472Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05192434",
      "title": "Trauma Intervention to Optimize PrEP Among Women Who Inject Drugs",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV Infections",
        "Opioid Use",
        "Trauma, Psychological"
      ],
      "interventions": [
        {
          "name": "Expressive Writing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Contingency Management",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Drexel University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 219,
      "start_date": "2022-06-17",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-12-23",
      "last_synced_at": "2026-09-27T07:18:36.472Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05192434"
    },
    {
      "nct_id": "NCT05619497",
      "title": "The OPENS Trial: Offering Women PrEP (Aim 2)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Human Immunodeficiency Virus",
        "Human Immunodeficiency Virus Transmission",
        "Sexually Transmitted Diseases"
      ],
      "interventions": [
        {
          "name": "Clinic-wide Trainings",
          "type": "OTHER"
        },
        {
          "name": "Clinic-wide Trainings and HIV Prevention Decision Support Tool (DST)",
          "type": "OTHER"
        },
        {
          "name": "Standard Care with the HIV Prevention Decision Support Tool (DST)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 141,
      "start_date": "2022-12-02",
      "completion_date": "2024-11-01",
      "has_results": false,
      "last_update_posted_date": "2025-11-25",
      "last_synced_at": "2026-09-27T07:18:36.472Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05619497"
    },
    {
      "nct_id": "NCT07136363",
      "title": "RESTORE Study R61 Phase: Recovery and Engagement for Stimulant Users on Re-entry",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV",
        "Stimulant Use Disorder",
        "Justice Involved Populations",
        "HIV Prevention"
      ],
      "interventions": [
        {
          "name": "DynamiCare",
          "type": "DEVICE"
        },
        {
          "name": "Patient Navigation (PN)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2026-06-01",
      "completion_date": "2027-07-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-15",
      "last_synced_at": "2026-09-27T07:18:36.472Z",
      "location_count": 2,
      "location_summary": "New Haven, Connecticut • Dallas, Texas",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07136363"
    },
    {
      "nct_id": "NCT02611362",
      "title": "A Multilevel Gaming Intervention for Persons on PrEP",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "MSM",
        "PrEP",
        "HIV Risk"
      ],
      "interventions": [
        {
          "name": "IMB Gaming Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Rhode Island Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 82,
      "start_date": "2015-04",
      "completion_date": "2019-12",
      "has_results": true,
      "last_update_posted_date": "2021-01-12",
      "last_synced_at": "2026-09-27T07:18:36.472Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02611362"
    },
    {
      "nct_id": "NCT04804072",
      "title": "INTEGRA: A Vanguard Study of Health Service Delivery in a Mobile Health Delivery Unit",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV Infections",
        "Drug Use",
        "Opioid Use",
        "Opioid-use Disorder"
      ],
      "interventions": [
        {
          "name": "Medication for opioid-use disorder (MOUD) for opioid-use disorder (OUD)",
          "type": "DRUG"
        },
        {
          "name": "HIV testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "HIV treatment for participants living with HIV not already in care",
          "type": "DRUG"
        },
        {
          "name": "PrEP for participants without HIV",
          "type": "DRUG"
        },
        {
          "name": "Testing and referral for vaccination or treatment for hepatitis A virus (HAV) and hepatitis B virus (HBV)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Testing and referral for treatment for hepatitis C virus (HCV)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Sexually transmitted infection (STI) testing and treatment",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Primary care",
          "type": "OTHER"
        },
        {
          "name": "Harm reduction services",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Peer navigation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "COVID-19 testing and referral for further evaluation, care and/or treatment",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIAGNOSTIC_TEST",
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "HIV Prevention Trials Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 447,
      "start_date": "2021-06-02",
      "completion_date": "2024-12-17",
      "has_results": true,
      "last_update_posted_date": "2026-06-10",
      "last_synced_at": "2026-09-27T07:18:36.472Z",
      "location_count": 5,
      "location_summary": "Los Angeles, California • Washington D.C., District of Columbia • The Bronx, New York + 2 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04804072"
    },
    {
      "nct_id": "NCT06810973",
      "title": "Substance Use and HIV Action for Reentry and Engagement.",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV"
      ],
      "interventions": [
        {
          "name": "SUCCESS-E",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced Standard of Care",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Key Informant Interviews",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2025-06-09",
      "completion_date": "2026-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-08-11",
      "last_synced_at": "2026-09-27T07:18:36.472Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06810973"
    },
    {
      "nct_id": "NCT04925752",
      "title": "Study of Lenacapavir for HIV Pre-Exposure Prophylaxis in People Who Are at Risk for HIV Infection",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pre-Exposure Prophylaxis of HIV Infection"
      ],
      "interventions": [
        {
          "name": "Oral Lenacapavir (LEN)",
          "type": "DRUG"
        },
        {
          "name": "F/TDF",
          "type": "DRUG"
        },
        {
          "name": "Sub-cutaneous (SC) Lenacapavir (LEN)",
          "type": "DRUG"
        },
        {
          "name": "Placebo SC LEN",
          "type": "DRUG"
        },
        {
          "name": "PTM F/TDF",
          "type": "DRUG"
        },
        {
          "name": "PTM Oral LEN",
          "type": "DRUG"
        },
        {
          "name": "F/TAF (for US participants only)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Gilead Sciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 3292,
      "start_date": "2021-06-28",
      "completion_date": "2028-08",
      "has_results": true,
      "last_update_posted_date": "2025-12-23",
      "last_synced_at": "2026-09-27T07:18:36.472Z",
      "location_count": 60,
      "location_summary": "Birmingham, Alabama • Loma Linda, California • Los Angeles, California + 43 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04925752"
    },
    {
      "nct_id": "NCT05087927",
      "title": "Study for IFE4PrEP Intervention on PrEP Uptake by Southern African American Women",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "HIV Prevention"
      ],
      "interventions": [
        {
          "name": "Gain framing plus demographically targeted photos",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Loss framing plus demographically targeted photos",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Gain framing plus not demographically targeted photos",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Loss framing plus not demographically targeted photos",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 31,
      "start_date": "2023-04-18",
      "completion_date": "2024-03-10",
      "has_results": false,
      "last_update_posted_date": "2024-09-20",
      "last_synced_at": "2026-09-27T07:18:36.472Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05087927"
    }
  ]
}