{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Prazosin+medication&page=2",
    "query": {
      "intervention": "Prazosin medication",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Prazosin+medication&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-26T16:18:31.782Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01062945",
      "title": "The Effects of Doxazosin on the Cardiovascular and Subjective Effects of Cocaine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Cocaine Addiction",
        "Cocaine Abuse",
        "Cocaine Dependence",
        "Substance Abuse"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Doxazosin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 13,
      "start_date": "2010-01",
      "completion_date": "2011-01",
      "has_results": false,
      "last_update_posted_date": "2012-07-27",
      "last_synced_at": "2026-09-26T16:18:31.782Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01062945"
    },
    {
      "nct_id": "NCT00223717",
      "title": "Treatment of Supine Hypertension in Autonomic Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Clonidine",
          "type": "DRUG"
        },
        {
          "name": "Nitroglycerin transdermal",
          "type": "DRUG"
        },
        {
          "name": "Dipyridamole/ Aspirin (Aggrenox)",
          "type": "DRUG"
        },
        {
          "name": "Desmopressin (DDAVP)",
          "type": "DRUG"
        },
        {
          "name": "Sildenafil",
          "type": "DRUG"
        },
        {
          "name": "Nifedipine",
          "type": "DRUG"
        },
        {
          "name": "Hydralazine",
          "type": "DRUG"
        },
        {
          "name": "Hydrochlorothiazide",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Bosentan",
          "type": "DRUG"
        },
        {
          "name": "Diltiazem",
          "type": "DRUG"
        },
        {
          "name": "Eplerenone",
          "type": "DRUG"
        },
        {
          "name": "guanfacine",
          "type": "DRUG"
        },
        {
          "name": "L-arginine",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "captopril",
          "type": "DRUG"
        },
        {
          "name": "carbidopa",
          "type": "DRUG"
        },
        {
          "name": "losartan",
          "type": "DRUG"
        },
        {
          "name": "metoprolol tartrate",
          "type": "DRUG"
        },
        {
          "name": "nebivolol hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "prazosin hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "tamsulosin hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "Head-up tilt.",
          "type": "OTHER"
        },
        {
          "name": "aliskiren",
          "type": "DRUG"
        },
        {
          "name": "Local heat stress",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 152,
      "start_date": "2001-01",
      "completion_date": "2017-01",
      "has_results": false,
      "last_update_posted_date": "2017-10-13",
      "last_synced_at": "2026-09-26T16:18:31.782Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00223717"
    },
    {
      "nct_id": "NCT03339258",
      "title": "A Randomized Controlled Trial of Doxazosin for Nightmares, Sleep Disturbance, and Non-Nightmare Clinical Symptoms in PTSD",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Stress Disorders, Post-Traumatic"
      ],
      "interventions": [
        {
          "name": "Doxazosin Mesylate, Extended Release",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "San Francisco Veterans Affairs Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 80,
      "start_date": "2018-04-15",
      "completion_date": "2024-06",
      "has_results": false,
      "last_update_posted_date": "2024-05-01",
      "last_synced_at": "2026-09-26T16:18:31.782Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03339258"
    },
    {
      "nct_id": "NCT03710642",
      "title": "Prazosin for Agitation in Alzheimer's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Alzheimer's Disease",
        "Disruptive Behavior"
      ],
      "interventions": [
        {
          "name": "Prazosin",
          "type": "DRUG"
        },
        {
          "name": "Placebo oral capsule",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alzheimer's Disease Cooperative Study (ADCS)",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 35,
      "start_date": "2018-10-23",
      "completion_date": "2022-01-05",
      "has_results": true,
      "last_update_posted_date": "2023-02-06",
      "last_synced_at": "2026-09-26T16:18:31.782Z",
      "location_count": 14,
      "location_summary": "Sun City, Arizona • Los Angeles, California • San Diego, California + 10 more",
      "locations": [
        {
          "city": "Sun City",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Simi Valley",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03710642"
    },
    {
      "nct_id": "NCT00006294",
      "title": "Genetics of Hypertension Associated Treatments (GenHAT)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cardiovascular Diseases",
        "Heart Diseases",
        "Hypertension",
        "Coronary Disease",
        "Myocardial Infarction"
      ],
      "interventions": [
        {
          "name": "Chlorthalidone",
          "type": "DRUG"
        },
        {
          "name": "Lisinopril",
          "type": "DRUG"
        },
        {
          "name": "Amlodipine",
          "type": "DRUG"
        },
        {
          "name": "Doxazosin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Donna Arnett, 257-5678",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 37939,
      "start_date": "1999-09",
      "completion_date": "2005-08",
      "has_results": false,
      "last_update_posted_date": "2024-04-26",
      "last_synced_at": "2026-09-26T16:18:31.782Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00006294"
    },
    {
      "nct_id": "NCT03221751",
      "title": "Prazosin and Cerebrospinal Fluid (CSF) Biomarkers in Mild Traumatic Brain Injury (mTBI)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Dementia"
      ],
      "interventions": [
        {
          "name": "prazosin hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 9,
      "start_date": "2016-12-01",
      "completion_date": "2023-12-05",
      "has_results": true,
      "last_update_posted_date": "2024-02-26",
      "last_synced_at": "2026-09-26T16:18:31.782Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03221751"
    },
    {
      "nct_id": "NCT00713739",
      "title": "Alfuzosin for Medical Expulsion Therapy of Ureteral Stones",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Kidney Stones"
      ],
      "interventions": [
        {
          "name": "Alfuzosin",
          "type": "DRUG"
        },
        {
          "name": "nifedipine",
          "type": "DRUG"
        },
        {
          "name": "doxazosin",
          "type": "DRUG"
        },
        {
          "name": "prazosin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "United States Naval Medical Center, San Diego",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 240,
      "start_date": "2008-01",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2012-04-27",
      "last_synced_at": "2026-09-26T16:18:31.782Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00713739"
    },
    {
      "nct_id": "NCT01637584",
      "title": "Neurobiology of Sleep and Sleep Treatment Response in Returning Veterans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Non PTSD",
        "PTSD"
      ],
      "interventions": [
        {
          "name": "Prazosin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 40,
      "start_date": "2010-04",
      "completion_date": "2012-11",
      "has_results": true,
      "last_update_posted_date": "2017-05-23",
      "last_synced_at": "2026-09-26T16:18:31.782Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01637584"
    },
    {
      "nct_id": "NCT01542372",
      "title": "Two Stepped Care Models for Posttraumatic Stress Disorder (PTSD) Among Cambodian Refugees With PTSD",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Posttraumatic Stress Disorder (PTSD)"
      ],
      "interventions": [
        {
          "name": "Medication augmentation",
          "type": "DRUG"
        },
        {
          "name": "CBT",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "43 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "43 Years and older"
      },
      "enrollment_count": 114,
      "start_date": "2012-04",
      "completion_date": "2014-03",
      "has_results": true,
      "last_update_posted_date": "2017-05-17",
      "last_synced_at": "2026-09-26T16:18:31.782Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01542372"
    },
    {
      "nct_id": "NCT01953432",
      "title": "Pharmacogenetic Trial of Doxazosin for Treatment of Cocaine Abuse",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cocaine Dependence"
      ],
      "interventions": [
        {
          "name": "Doxazosin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 43,
      "start_date": "2014-04-01",
      "completion_date": "2017-10-01",
      "has_results": true,
      "last_update_posted_date": "2020-02-20",
      "last_synced_at": "2026-09-26T16:18:31.782Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01953432"
    }
  ]
}