{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pre-Exposure+Prophylaxis+and+Post-Exposure+Prophylaxis&page=2",
    "query": {
      "intervention": "Pre-Exposure Prophylaxis and Post-Exposure Prophylaxis",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pre-Exposure+Prophylaxis+and+Post-Exposure+Prophylaxis&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-27T05:42:46.934Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01874860",
      "title": "Skin Rash Study Before Chemotherapy in Colorectal & Head and Neck Cancer Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Colorectal Cancer",
        "Head and Neck Cancer"
      ],
      "interventions": [
        {
          "name": "Doxycycline",
          "type": "DRUG"
        },
        {
          "name": "Hydrocortisone 1% cream",
          "type": "DRUG"
        },
        {
          "name": "Sunscreen",
          "type": "OTHER"
        },
        {
          "name": "Moisturizer",
          "type": "OTHER"
        },
        {
          "name": "Clindamycin",
          "type": "DRUG"
        },
        {
          "name": "Medrol-dose pack (Steroid)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Louisville",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2013-08",
      "completion_date": "2018-07",
      "has_results": false,
      "last_update_posted_date": "2022-12-01",
      "last_synced_at": "2026-09-27T05:42:46.934Z",
      "location_count": 1,
      "location_summary": "Louisville, Kentucky",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01874860"
    },
    {
      "nct_id": "NCT06500884",
      "title": "A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Events",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Multiple Myeloma"
      ],
      "interventions": [
        {
          "name": "Talquetamab",
          "type": "DRUG"
        },
        {
          "name": "Prophylaxis A",
          "type": "DRUG"
        },
        {
          "name": "Prophylaxis B",
          "type": "DRUG"
        },
        {
          "name": "Prophylaxis C",
          "type": "DRUG"
        },
        {
          "name": "Prophylaxis D",
          "type": "DRUG"
        },
        {
          "name": "Ramantamig",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Janssen Research & Development, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 210,
      "start_date": "2024-08-26",
      "completion_date": "2030-05-30",
      "has_results": false,
      "last_update_posted_date": "2026-09-25",
      "last_synced_at": "2026-09-27T05:42:46.934Z",
      "location_count": 9,
      "location_summary": "San Francisco, California • Denver, Colorado • New Haven, Connecticut + 6 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06500884"
    },
    {
      "nct_id": "NCT02467374",
      "title": "Fear Extinction and Mechanisms of Change in Obsessive Compulsive Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obsessive Compulsive Disorder"
      ],
      "interventions": [
        {
          "name": "Behavior Therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 54,
      "start_date": "2014-12",
      "completion_date": "2019-07-22",
      "has_results": false,
      "last_update_posted_date": "2022-03-31",
      "last_synced_at": "2026-09-27T05:42:46.934Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02467374"
    },
    {
      "nct_id": "NCT04109118",
      "title": "Benzodiazepine Discontinuation in Opioid Agonist Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Substance Use Disorders"
      ],
      "interventions": [
        {
          "name": "Distress Tolerance - Benzodiazepine Discontinuation (DT-BD)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "BZD discontinuation protocol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "Boston Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "2021-03-18",
      "completion_date": "2021-07-08",
      "has_results": true,
      "last_update_posted_date": "2022-02-11",
      "last_synced_at": "2026-09-27T05:42:46.934Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04109118"
    },
    {
      "nct_id": "NCT05520905",
      "title": "TelePrEP for At-risk Youth in Colorado",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hiv"
      ],
      "interventions": [
        {
          "name": "TelePrEP",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "24 Years",
        "sex": "MALE",
        "summary": "14 Years to 24 Years · Male only"
      },
      "enrollment_count": 100,
      "start_date": "2023-04-18",
      "completion_date": "2025-04",
      "has_results": false,
      "last_update_posted_date": "2024-05-08",
      "last_synced_at": "2026-09-27T05:42:46.934Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05520905"
    },
    {
      "nct_id": "NCT05406583",
      "title": "A Study of the Safety, Tolerability, and Pharmacokinetics of Dolutegravir in Neonates Exposed to HIV-1",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "HIV"
      ],
      "interventions": [
        {
          "name": "Dolutegravir 0.5 mg/kg liquid suspension (starts at 0-5 days of life)",
          "type": "DRUG"
        },
        {
          "name": "Dolutegravir 5 mg Dispersible Tablets (single doses)",
          "type": "DRUG"
        },
        {
          "name": "Dolutegravir 5 mg Dispersible Tablets (chronic dose)",
          "type": "DRUG"
        },
        {
          "name": "Dolutegravir 0.5 mg/kg liquid suspension (starts at 2-5 days of life)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 96,
      "start_date": "2022-10-05",
      "completion_date": "2025-05-22",
      "has_results": true,
      "last_update_posted_date": "2026-05-22",
      "last_synced_at": "2026-09-27T05:42:46.934Z",
      "location_count": 8,
      "location_summary": "Los Angeles, California • Aurora, Colorado • Atlanta, Georgia + 4 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05406583"
    },
    {
      "nct_id": "NCT05619497",
      "title": "The OPENS Trial: Offering Women PrEP (Aim 2)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Human Immunodeficiency Virus",
        "Human Immunodeficiency Virus Transmission",
        "Sexually Transmitted Diseases"
      ],
      "interventions": [
        {
          "name": "Clinic-wide Trainings",
          "type": "OTHER"
        },
        {
          "name": "Clinic-wide Trainings and HIV Prevention Decision Support Tool (DST)",
          "type": "OTHER"
        },
        {
          "name": "Standard Care with the HIV Prevention Decision Support Tool (DST)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 141,
      "start_date": "2022-12-02",
      "completion_date": "2024-11-01",
      "has_results": false,
      "last_update_posted_date": "2025-11-25",
      "last_synced_at": "2026-09-27T05:42:46.934Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05619497"
    },
    {
      "nct_id": "NCT01327651",
      "title": "The ADAPT Study: Use of Emtricitabine and Tenofovir Disoproxil Fumarate for Pre-Exposure Prophylaxis (PrEP)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "HIV Infections"
      ],
      "interventions": [
        {
          "name": "Daily dosing",
          "type": "DRUG"
        },
        {
          "name": "Time-driven dosing",
          "type": "DRUG"
        },
        {
          "name": "Event-driven dosing",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "HIV Prevention Trials Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 622,
      "start_date": "2011-08",
      "completion_date": "2014-12",
      "has_results": true,
      "last_update_posted_date": "2025-03-27",
      "last_synced_at": "2026-09-27T05:42:46.934Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01327651"
    },
    {
      "nct_id": "NCT05072093",
      "title": "Parrying the Pitfalls of PrEP: Project PEACH",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "HIV",
        "STI"
      ],
      "interventions": [
        {
          "name": "PrEP discontinuation intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Offering of on-demand oral PrEP",
          "type": "DRUG"
        },
        {
          "name": "Offering of STI PEP",
          "type": "DRUG"
        },
        {
          "name": "Injectable PrEP",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "MALE",
        "summary": "18 Years to 45 Years · Male only"
      },
      "enrollment_count": 240,
      "start_date": "2021-11-20",
      "completion_date": "2025-03-31",
      "has_results": true,
      "last_update_posted_date": "2026-04-01",
      "last_synced_at": "2026-09-27T05:42:46.934Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05072093"
    },
    {
      "nct_id": "NCT04417946",
      "title": "Peer-led Social Media Intervention to Prevent HIV Among Young Men Who Have Sex With Men (YMSM)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pre-Exposure Prophylaxis",
        "Hiv",
        "Men"
      ],
      "interventions": [
        {
          "name": "PrEP messages",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Heath messages",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "29 Years",
        "sex": "MALE",
        "summary": "18 Years to 29 Years · Male only"
      },
      "enrollment_count": 227,
      "start_date": "2018-06-05",
      "completion_date": "2023-04-01",
      "has_results": false,
      "last_update_posted_date": "2023-10-23",
      "last_synced_at": "2026-09-27T05:42:46.934Z",
      "location_count": 2,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04417946"
    }
  ]
}