{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pre-Medication%3A+Zofran", "query": { "intervention": "Pre-Medication: Zofran" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 38, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pre-Medication%3A+Zofran&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-15T21:22:40.779Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03448068", "title": "Perioperative Ketamine for Pain With Gastric Bypass", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Laparoscopic Gastric Bypass Surgery", "Ketamine" ], "interventions": [ { "name": "Ketamine", "type": "DRUG" }, { "name": "Standard therapy", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "69 Years", "sex": "ALL", "summary": "18 Years to 69 Years" }, "enrollment_count": 34, "start_date": "2018-04-16", "completion_date": "2020-01-09", "has_results": true, "last_update_posted_date": "2021-04-29", "last_synced_at": "2026-09-15T21:22:40.779Z", "location_count": 1, "location_summary": "Phoenix, Arizona", "locations": [ { "city": "Phoenix", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT03448068" }, { "nct_id": "NCT06938581", "title": "ERAS Protocols in Breast Conserving Surgery", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Breast Cancer", "Postoperative Recovery" ], "interventions": [ { "name": "ERAS Protocol", "type": "OTHER" }, { "name": "Standard Perioperative Care", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Nebraska", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "19 Years", "maximum_age": null, "sex": "ALL", "summary": "19 Years and older" }, "enrollment_count": 260, "start_date": "2025-07-11", "completion_date": "2029-02", "has_results": false, "last_update_posted_date": "2026-05-19", "last_synced_at": "2026-09-15T21:22:40.779Z", "location_count": 1, "location_summary": "Omaha, Nebraska", "locations": [ { "city": "Omaha", "state": "Nebraska" } ], "official_url": "https://clinicaltrials.gov/study/NCT06938581" }, { "nct_id": "NCT05473897", "title": "Cooling Helmets to Decrease Concussion Symptoms", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Concussion, Mild", "TBI (Traumatic Brain Injury)" ], "interventions": [ { "name": "Catalyst Cryohelmet", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Corewell Health South", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "19 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "19 Years to 65 Years" }, "enrollment_count": 18, "start_date": "2022-06-23", "completion_date": "2024-04-01", "has_results": false, "last_update_posted_date": "2024-11-29", "last_synced_at": "2026-09-15T21:22:40.779Z", "location_count": 1, "location_summary": "Saint Joseph, Michigan", "locations": [ { "city": "Saint Joseph", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT05473897" }, { "nct_id": "NCT05021263", "title": "Does IV Magnesium Improve Quality of Recovery With ERAS Protocols in Laparoscopic Colorectal Surgery?", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Colo-rectal Cancer", "Anesthesia" ], "interventions": [ { "name": "IV Medications", "type": "DRUG" }, { "name": "placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Thomas Jefferson University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 90, "start_date": "2022-05-27", "completion_date": "2023-12-29", "has_results": false, "last_update_posted_date": "2024-04-09", "last_synced_at": "2026-09-15T21:22:40.779Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT05021263" }, { "nct_id": "NCT02410460", "title": "Anesthetics in Rhytidoplasty - A Comparison Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Rhytidoplasty" ], "interventions": [ { "name": "clonidine", "type": "DRUG" }, { "name": "glycopyrrolate", "type": "DRUG" }, { "name": "propofol", "type": "DRUG" }, { "name": "ketamine", "type": "DRUG" }, { "name": "marcaine", "type": "DRUG" }, { "name": "scopolamine", "type": "DRUG" }, { "name": "midazolam", "type": "DRUG" }, { "name": "ondansetron", "type": "DEVICE" }, { "name": "metoclopramide", "type": "DRUG" }, { "name": "lidocaine", "type": "DRUG" }, { "name": "famotidine", "type": "DRUG" }, { "name": "desflurane", "type": "DRUG" }, { "name": "sevoflurane", "type": "DRUG" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Mercy Facial Plastic Surgery Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 30, "start_date": "2013-09", "completion_date": "2014-06", "has_results": false, "last_update_posted_date": "2015-04-07", "last_synced_at": "2026-09-15T21:22:40.779Z", "location_count": 1, "location_summary": "Springfield, Missouri", "locations": [ { "city": "Springfield", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT02410460" }, { "nct_id": "NCT02772965", "title": "Low Dose Oral Methotrexate in Pediatric Crohn's Disease Patients Initiating Anti-Tumor Necrosis Factor (Anti-TNF) Therapy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pediatric Crohn's Disease" ], "interventions": [ { "name": "Methotrexate", "type": "DRUG" }, { "name": "Sugar pill (placebo)", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of North Carolina, Chapel Hill", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "20 Years", "sex": "ALL", "summary": "Up to 20 Years" }, "enrollment_count": 306, "start_date": "2016-10", "completion_date": "2022-04-07", "has_results": true, "last_update_posted_date": "2023-04-12", "last_synced_at": "2026-09-15T21:22:40.779Z", "location_count": 32, "location_summary": "Birmingham, Alabama • Alto, California • New Haven, Connecticut + 27 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Alto", "state": "California" }, { "city": "New Haven", "state": "Connecticut" }, { "city": "Wilmington", "state": "Delaware" }, { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02772965" }, { "nct_id": "NCT04743661", "title": "131I-Omburtamab, in Recurrent Medulloblastoma and Ependymoma", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Recurrent Medulloblastoma", "Recurrent Ependymoma" ], "interventions": [ { "name": "Irinotecan", "type": "DRUG" }, { "name": "Temozolomide", "type": "DRUG" }, { "name": "Bevacizumab", "type": "DRUG" }, { "name": "Omburtamab I-131", "type": "DRUG" }, { "name": "Liothyronine", "type": "DRUG" }, { "name": "SSKI", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" }, { "name": "Antipyretic", "type": "DRUG" }, { "name": "Antihistamine", "type": "DRUG" }, { "name": "anti-emetics", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pediatric Brain Tumor Consortium", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "21 Years", "sex": "ALL", "summary": "Up to 21 Years" }, "enrollment_count": 62, "start_date": "2022-04-04", "completion_date": "2027-09-30", "has_results": false, "last_update_posted_date": "2026-07-28", "last_synced_at": "2026-09-15T21:22:40.779Z", "location_count": 3, "location_summary": "Los Angeles, California • New York, New York • Cincinnati, Ohio", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "New York", "state": "New York" }, { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT04743661" }, { "nct_id": "NCT01566838", "title": "Continuous Subpleural Infusion of Bupivacaine", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Postoperative Pain" ], "interventions": [ { "name": "Subpleural pain catheter with infusion of 0.125% bupivacaine", "type": "DRUG" }, { "name": "Standard acute pain management", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Inova Health Care Services", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 83, "start_date": "2012-10", "completion_date": "2015-12", "has_results": true, "last_update_posted_date": "2017-12-20", "last_synced_at": "2026-09-15T21:22:40.779Z", "location_count": 1, "location_summary": "Falls Church, Virginia", "locations": [ { "city": "Falls Church", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT01566838" }, { "nct_id": "NCT02542384", "title": "A Study Evaluating the Overall Pain Relief and Safety of Intravenous (IV) CR845 in Patients Undergoing Abdominal Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Post Abdominal Surgery Pain" ], "interventions": [ { "name": "CR845 IV 1 mcg/kg", "type": "DRUG" }, { "name": "CR845 IV 0.5 mcg/kg", "type": "DRUG" }, { "name": "Placebo IV", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Cara Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 451, "start_date": "2015-09", "completion_date": "2018-06", "has_results": false, "last_update_posted_date": "2019-05-31", "last_synced_at": "2026-09-15T21:22:40.779Z", "location_count": 23, "location_summary": "Sheffield, Alabama • New Haven, Connecticut • Bradenton, Florida + 20 more", "locations": [ { "city": "Sheffield", "state": "Alabama" }, { "city": "New Haven", "state": "Connecticut" }, { "city": "Bradenton", "state": "Florida" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Maitland", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02542384" }, { "nct_id": "NCT04766996", "title": "PROUD Study - Preventing Opioid Use Disorders", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Anesthesia", "Opioid Use" ], "interventions": [ { "name": "Guided mindfulness exercises", "type": "BEHAVIORAL" }, { "name": "Self-administered aromatherapy", "type": "OTHER" }, { "name": "Baby aspirin", "type": "DRUG" }, { "name": "Tylenol/Acetaminophen", "type": "DRUG" }, { "name": "Pregabalin", "type": "DRUG" }, { "name": "Prednisone", "type": "DRUG" }, { "name": "Meloxicam", "type": "DRUG" }, { "name": "Prilosec", "type": "DRUG" }, { "name": "Tramadol", "type": "DRUG" }, { "name": "Voltaren", "type": "DRUG" }, { "name": "Zofran", "type": "DRUG" }, { "name": "Pepcid", "type": "DRUG" }, { "name": "Reglan", "type": "DRUG" }, { "name": "Versed", "type": "DRUG" }, { "name": "Lidocaine", "type": "DRUG" }, { "name": "Propofol", "type": "DRUG" }, { "name": "Ancef", "type": "DRUG" }, { "name": "Tranexamic Acid (TXA)", "type": "DRUG" }, { "name": "Decadron", "type": "DRUG" }, { "name": "Bupivacaine hydrochloride", "type": "DRUG" }, { "name": "Toradol", "type": "DRUG" } ], "intervention_types": [ "BEHAVIORAL", "OTHER", "DRUG" ], "sponsor": "Emory University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 57, "start_date": "2021-05-17", "completion_date": "2021-12-27", "has_results": true, "last_update_posted_date": "2023-06-22", "last_synced_at": "2026-09-15T21:22:40.779Z", "location_count": 1, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT04766996" } ] }