{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pre-Quit+Nicotine+Patch+%2B+Pre-Quit+Nicotine+Gum",
    "query": {
      "intervention": "Pre-Quit Nicotine Patch + Pre-Quit Nicotine Gum"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 22,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pre-Quit+Nicotine+Patch+%2B+Pre-Quit+Nicotine+Gum&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-30T05:19:37.296Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00701896",
      "title": "Smoking Cessation Using Motivational Therapy and Varenicline",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking",
        "HIV Infections"
      ],
      "interventions": [
        {
          "name": "Varenicline tartrate",
          "type": "DRUG"
        },
        {
          "name": "Nicotine Replacement Therapy",
          "type": "DRUG"
        },
        {
          "name": "Biological Control",
          "type": "OTHER"
        },
        {
          "name": "Motivational Interview",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "Philip Diaz",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 294,
      "start_date": "2008-10-03",
      "completion_date": "2013-06-20",
      "has_results": true,
      "last_update_posted_date": "2021-01-15",
      "last_synced_at": "2026-09-30T05:19:37.296Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00701896"
    },
    {
      "nct_id": "NCT01990079",
      "title": "Use of Technological Advances to Prevent Smoking Relapse Among Smokers With PTSD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "PTSD",
        "Smoking"
      ],
      "interventions": [
        {
          "name": "Bupropion",
          "type": "DRUG"
        },
        {
          "name": "nicotine replacement therapy",
          "type": "DRUG"
        },
        {
          "name": "Smoking cessation counseling",
          "type": "OTHER"
        },
        {
          "name": "mobile contingency management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Stay Quit Coach",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 15,
      "start_date": "2013-12",
      "completion_date": "2015-08",
      "has_results": false,
      "last_update_posted_date": "2026-05-18",
      "last_synced_at": "2026-09-30T05:19:37.296Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01990079"
    },
    {
      "nct_id": "NCT01087905",
      "title": "Improving the Population-Wide Effectiveness of U.S. Tobacco Cessation Quitlines",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Smoking",
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Nicotine patch",
          "type": "DRUG"
        },
        {
          "name": "Nicotine gum",
          "type": "DRUG"
        },
        {
          "name": "CMAC",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 987,
      "start_date": "2010-04",
      "completion_date": "2011-11",
      "has_results": true,
      "last_update_posted_date": "2016-12-08",
      "last_synced_at": "2026-09-30T05:19:37.296Z",
      "location_count": 2,
      "location_summary": "Seattle, Washington • Madison, Wisconsin",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        },
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01087905"
    },
    {
      "nct_id": "NCT01120704",
      "title": "Evaluation of Treatments to Improve Smoking Cessation Medication Adherence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Smoking",
        "Smoking Cessation",
        "Adherence",
        "Nicotine Dependence",
        "Motivation"
      ],
      "interventions": [
        {
          "name": "Short Term Combination Nicotine Replacement Therapy (patch + gum)",
          "type": "DRUG"
        },
        {
          "name": "Long Term Combination Nicotine Replacement Therapy (patch + gum)",
          "type": "DRUG"
        },
        {
          "name": "Intensive Maintenance Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitive Medication Adherence Counseling (CAM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Electronic Medication Monitoring Device (the Helping Hand) + Feedback",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Automated Adherence Prompting Phone Calls",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 544,
      "start_date": "2010-06",
      "completion_date": "2014-05",
      "has_results": true,
      "last_update_posted_date": "2015-12-11",
      "last_synced_at": "2026-09-30T05:19:37.296Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01120704"
    },
    {
      "nct_id": "NCT02995915",
      "title": "Mobile Contingency Management for Concurrent Abstinence From Alcohol and Smoking",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Smoking Cessation",
        "Alcohol Drinking"
      ],
      "interventions": [
        {
          "name": "Nicotine Replacement Therapy",
          "type": "OTHER"
        },
        {
          "name": "Bupropion",
          "type": "DRUG"
        },
        {
          "name": "Cognitive Behavioral Treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mobile Contingency Management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mobile Monitoring",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 45,
      "start_date": "2016-11",
      "completion_date": "2020-03-02",
      "has_results": true,
      "last_update_posted_date": "2021-04-28",
      "last_synced_at": "2026-09-30T05:19:37.296Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02995915"
    },
    {
      "nct_id": "NCT01116986",
      "title": "Identifying Optimal Smoking Cessation Intervention Components (Cessation)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Smoking",
        "Smoking Cessation",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Counseling before quit attempt",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Minimal In-person counseling during quit attempt",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Intensive in-person counseling during the quit attempt",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Minimal phone counseling during the quit attempt",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Intensive phone counseling during the quit attempt",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Long Term Nicotine Patch+ Nicotine Gum During Quit Attempt",
          "type": "DRUG"
        },
        {
          "name": "Short Term Nicotine Patch + Nicotine Gum during the quit attempt",
          "type": "DRUG"
        },
        {
          "name": "Pre-Quit Nicotine Gum",
          "type": "DRUG"
        },
        {
          "name": "Pre-Quit Nicotine Patch",
          "type": "DRUG"
        },
        {
          "name": "Pre-Quit Nicotine Patch + Pre-Quit Nicotine Gum",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 637,
      "start_date": "2010-06",
      "completion_date": "2014-05",
      "has_results": true,
      "last_update_posted_date": "2015-12-11",
      "last_synced_at": "2026-09-30T05:19:37.296Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01116986"
    },
    {
      "nct_id": "NCT02869451",
      "title": "Mobile Contingency Management for Marijuana and Tobacco Cessation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cigarette Smoking",
        "Marijuana Abuse"
      ],
      "interventions": [
        {
          "name": "bupropion",
          "type": "DRUG"
        },
        {
          "name": "transdermal nicotine patch",
          "type": "DRUG"
        },
        {
          "name": "Nicotine polacrilex",
          "type": "DRUG"
        },
        {
          "name": "nicotine lozenge",
          "type": "DRUG"
        },
        {
          "name": "counseling for marijuana and smoking cessation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "mobile contingency management",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 7,
      "start_date": "2016-08",
      "completion_date": "2017-05-17",
      "has_results": true,
      "last_update_posted_date": "2020-02-07",
      "last_synced_at": "2026-09-30T05:19:37.296Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02869451"
    },
    {
      "nct_id": "NCT04994444",
      "title": "Preloading With Nicotine Replacement Therapy in HIV-positive Smokers to Improve Self-Efficacy and Quit Attempts",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Tobacco Use Cessation"
      ],
      "interventions": [
        {
          "name": "Nicoderm CQ 21Mg/24Hr Transdermal System",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Brown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 49,
      "start_date": "2021-09-01",
      "completion_date": "2024-04-30",
      "has_results": true,
      "last_update_posted_date": "2025-04-06",
      "last_synced_at": "2026-09-30T05:19:37.296Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04994444"
    },
    {
      "nct_id": "NCT02994082",
      "title": "Treating Smokeless Tobacco Use in Rural Veterans",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smokeless Tobacco",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Tailored behavioral intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Behavioral activation for elevated depressive symptoms",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Post-cessation weight gain management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Alcohol use risk reduction",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nicotine replacement therapy - transdermal nicotine patch",
          "type": "DRUG"
        },
        {
          "name": "Nicotine replacement therapy - nicotine lozenge",
          "type": "DRUG"
        },
        {
          "name": "Nicotine replacement therapy - nicotine gum",
          "type": "DRUG"
        },
        {
          "name": "Bupropion sustained release",
          "type": "DRUG"
        },
        {
          "name": "Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Combination nicotine replacement therapy",
          "type": "DRUG"
        },
        {
          "name": "Combination nicotine replacement therapy + bupropion",
          "type": "DRUG"
        },
        {
          "name": "Tobacco quit line",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Educational materials",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "Mark Vander Weg",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 123,
      "start_date": "2016-12",
      "completion_date": "2020-05",
      "has_results": false,
      "last_update_posted_date": "2019-07-24",
      "last_synced_at": "2026-09-30T05:19:37.296Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02994082"
    },
    {
      "nct_id": "NCT07694492",
      "title": "Feasibility of a Medical-Legal Partnership Model to Connect Coal Miners QuitAid",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use Cessation",
        "Tobacco Use Disorder",
        "Nicotine Dependence",
        "Smokeless Tobacco Use"
      ],
      "interventions": [
        {
          "name": "QuitAid (pharmacist-delivered MTM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nicotine Replacement Therapy (NRT)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2026-09-01",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-10",
      "last_synced_at": "2026-09-30T05:19:37.296Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07694492"
    }
  ]
}