{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pre-Screening&page=46",
    "query": {
      "intervention": "Pre-Screening",
      "page": 46
    },
    "page_size": 10
  },
  "pagination": {
    "page": 46,
    "page_size": 10,
    "total_count": 1266,
    "total_pages": 127,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pre-Screening&page=47&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pre-Screening&page=45&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-05T15:49:28.811Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03972527",
      "title": "Photobiomodulation to Demonstrate Safety and Reduce the Incidence of Oral Mucositis in Adult Head & Neck Cancer Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Oral Mucositis (Ulcerative)",
        "Oral Mucositis (Ulcerative) Due to Radiation",
        "Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy",
        "Head and Neck Cancer"
      ],
      "interventions": [
        {
          "name": "Photobiomodulation",
          "type": "DEVICE"
        },
        {
          "name": "Routine Oral Care and Analgesia",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "MuReva Phototherapy Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 85,
      "start_date": "2022-08-05",
      "completion_date": "2024-07-18",
      "has_results": false,
      "last_update_posted_date": "2024-08-21",
      "last_synced_at": "2026-11-05T15:49:28.811Z",
      "location_count": 12,
      "location_summary": "Birmingham, Alabama • Long Beach, California • Miami, Florida + 9 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Edgewood",
          "state": "Kentucky"
        },
        {
          "city": "Shreveport",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03972527"
    },
    {
      "nct_id": "NCT01176474",
      "title": "Vaccine Combining Multiple Class I Peptides and Montanide ISA 51VG With Escalating Doses of Anti-PD-1 Antibody Nivolumab or Ipilimumab With Nivolumab For Patients With Resected Stages IIIC/ IV Melanoma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Melanoma (Skin)"
      ],
      "interventions": [
        {
          "name": "NY-ESO-1 157-165 (165V)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Nivolumab",
          "type": "DRUG"
        },
        {
          "name": "gp100:280-288 (288V)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Montanide ISA 51 vegetable grade (VG)",
          "type": "DRUG"
        },
        {
          "name": "Ipilimumab",
          "type": "DRUG"
        },
        {
          "name": "Apheresis Procedure",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "H. Lee Moffitt Cancer Center and Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 73,
      "start_date": "2010-08-13",
      "completion_date": "2023-01-06",
      "has_results": false,
      "last_update_posted_date": "2023-07-19",
      "last_synced_at": "2026-11-05T15:49:28.811Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01176474"
    },
    {
      "nct_id": "NCT03655223",
      "title": "Early Check: Expanded Screening in Newborns",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Spinal Muscular Atrophy",
        "Fragile X Syndrome",
        "Fragile X - Premutation",
        "Duchenne Muscular Dystrophy",
        "Hyperinsulinemic Hypoglycemia, Familial 1",
        "Diabetes Mellitus",
        "Adrenoleukodystrophy, Neonatal",
        "Medium-chain Acyl-CoA Dehydrogenase Deficiency",
        "Very Long Chain Acyl Coa Dehydrogenase Deficiency",
        "Beta-ketothiolase Deficiency",
        "Severe Combined Immunodeficiency Due to Adenosine Deaminase Deficiency",
        "Primary Hyperoxaluria Type 1",
        "Congenital Bile Acid Synthesis Defect Type 2",
        "Pyridoxine-Dependent Epilepsy",
        "Hereditary Fructose Intolerance",
        "Hypophosphatasia",
        "Hyperargininemia",
        "Mucopolysaccharidosis Type 6",
        "Argininosuccinic Aciduria",
        "Citrullinemia, Type I",
        "Wilson Disease",
        "Maple Syrup Urine Disease, Type 1A",
        "Maple Syrup Urine Disease, Type 1B",
        "Biotinidase Deficiency",
        "Neonatal Severe Primary Hyperparathyroidism",
        "Intrinsic Factor Deficiency",
        "Usher Syndrome Type 1D/F Digenic (Diagnosis)",
        "Cystic Fibrosis",
        "Stickler Syndrome Type 2",
        "Stickler Syndrome Type 1",
        "Alport Syndrome, Autosomal Recessive",
        "Alport Syndrome, X-Linked",
        "Carbamoyl Phosphate Synthetase I Deficiency Disease",
        "Carnitine Palmitoyl Transferase 1A Deficiency",
        "Carnitine Palmitoyltransferase II Deficiency",
        "Cystinosis",
        "Chronic Granulomatous Disease",
        "Cerebrotendinous Xanthomatoses",
        "Maple Syrup Urine Disease, Type 2",
        "Severe Combined Immunodeficiency Due to DCLRE1C Deficiency",
        "Thyroid Dyshormonogenesis 6",
        "Thyroid Dyshormonogenesis 5",
        "Supravalvar Aortic Stenosis",
        "Factor X Deficiency",
        "Hemophilia A",
        "Hemophilia B",
        "Tyrosinemia, Type I",
        "Fructose 1,6 Bisphosphatase Deficiency",
        "Glycogen Storage Disease Type I",
        "G6PD Deficiency",
        "Glycogen Storage Disease II",
        "Galactokinase Deficiency",
        "Mucopolysaccharidosis Type IV A",
        "Galactosemias",
        "Guanidinoacetate Methyltransferase Deficiency",
        "Agat Deficiency",
        "Glutaryl-CoA Dehydrogenase Deficiency",
        "Gtp Cyclohydrolase I Deficiency",
        "Hyperinsulinism-Hyperammonemia Syndrome",
        "Primary Hyperoxaluria Type 2",
        "3-Hydroxyacyl-CoA Dehydrogenase Deficiency",
        "Long-chain 3-hydroxyacyl-CoA Dehydrogenase Deficiency",
        "Mitochondrial Trifunctional Protein Deficiency",
        "Sickle Cell Disease",
        "Beta-Thalassemia",
        "Holocarboxylase Synthetase Deficiency",
        "3-Hydroxy-3-Methylglutaric Aciduria",
        "Primary Hyperoxaluria Type 3",
        "Hermansky-Pudlak Syndrome 1",
        "Hermansky-Pudlak Syndrome 4",
        "Apparent Mineralocorticoid Excess",
        "HSDB",
        "CBAS1",
        "Mucopolysaccharidosis Type 2",
        "Mucopolysaccharidosis Type 1",
        "Severe Combined Immunodeficiency, X Linked",
        "Severe Combined Immunodeficiency Due to IL-7Ralpha Deficiency",
        "Diabetes Mellitus, Permanent Neonatal",
        "Isovaleric Acidemia",
        "Severe Combined Immunodeficiency T-Cell Negative B-Cell Positive Due to Janus Kinase-3 Deficiency (Disorder)",
        "Jervell and Lange-Nielsen Syndrome 2",
        "Hyperinsulinemic Hypoglycemia, Familial, 2",
        "Diabetes Mellitus, Permanent Neonatal, With Neurologic Features",
        "Jervell and Lange-Nielsen Syndrome 1",
        "Lysosomal Acid Lipase Deficiency",
        "CblF",
        "3-Methylcrotonyl CoA Carboxylase 1 Deficiency",
        "3-Methylcrotonyl CoA Carboxylase 2 Deficiency",
        "Waardenburg Syndrome Type 2A",
        "Methylmalonic Aciduria cblA Type",
        "Methylmalonic Aciduria cblB Type",
        "Methylmalonic Aciduria and Homocystinuria Type cblC",
        "MAHCD",
        "Methylmalonic Aciduria Due to Methylmalonyl-CoA Mutase Deficiency",
        "Congenital Disorder of Glycosylation Type 1B",
        "Mthfr Deficiency",
        "Methylcobalamin Deficiency Type Cbl G (Disorder)",
        "Methylcobalamin Deficiency Type cblE",
        "Usher Syndrome, Type 1B",
        "N-acetylglutamate Synthase Deficiency",
        "Ornithine Transcarbamylase Deficiency",
        "Phenylketonurias",
        "Waardenburg Syndrome Type 1",
        "Congenital Hypothyroidism",
        "Propionic Acidemia",
        "Usher Syndrome, Type 1F",
        "Pancreatic Agenesis 1",
        "Hereditary Hypophosphatemic Rickets",
        "Glycogen Storage Disease IXB",
        "Glycogen Storage Disease IXC",
        "MOWS",
        "Epilepsy, Early-Onset, Vitamin B6-Dependent",
        "Pyridoxal Phosphate-Responsive Seizures",
        "Pituitary Hormone Deficiency, Combined, 1",
        "Ptsd",
        "Dihydropteridine Reductase Deficiency",
        "Severe Combined Immunodeficiency Due to RAG1 Deficiency",
        "Severe Combined Immunodeficiency Due to RAG2 Deficiency",
        "Retinoblastoma",
        "Multiple Endocrine Neoplasia Type 2B",
        "Pseudohypoaldosteronism, Type I",
        "Liddle Syndrome",
        "Biotin-Responsive Basal Ganglia Disease",
        "SCD",
        "DIAR1",
        "GSD1C",
        "Acrodermatitis Enteropathica",
        "Thyroid Dyshormonogenesis 1",
        "Riboflavin Transporter Deficiency",
        "Waardenburg Syndrome, Type 2E",
        "SRD",
        "Congenital Lipoid Adrenal Hyperplasia Due to STAR Deficiency",
        "Barth Syndrome",
        "Adrenocorticotropic Hormone Deficiency",
        "Transcobalamin II Deficiency",
        "Thyroid Dyshormonogenesis 3",
        "Segawa Syndrome, Autosomal Recessive",
        "Autosomal Recessive Nonsyndromic Hearing Loss",
        "Thyroid Dyshormonogenesis 2A",
        "Congenital Isolated Thyroid Stimulating Hormone Deficiency",
        "Hypothyroidism Due to TSH Receptor Mutations",
        "Usher Syndrome Type 1C",
        "Usher Syndrome Type 1G (Diagnosis)",
        "Von Willebrand Disease, Type 3",
        "Combined Immunodeficiency Due to ZAP70 Deficiency",
        "Adenine Phosphoribosyltransferase Deficiency",
        "Metachromatic Leukodystrophy",
        "Canavan Disease",
        "Menkes Disease",
        "Carbonic Anhydrase VA Deficiency",
        "Developmental and Epileptic Encephalopathy 2",
        "17 Alpha-Hydroxylase Deficiency",
        "Smith-Lemli-Opitz Syndrome",
        "Krabbe Disease",
        "Glutathione Synthetase Deficiency",
        "Mucopolysaccharidosis Type 7",
        "Rett Syndrome",
        "Molybdenum Cofactor Deficiency, Type A",
        "Niemann-Pick Disease, Type C1",
        "Niemann-Pick Disease Type C2",
        "Ornithine Aminotransferase Deficiency",
        "3-Phosphoglycerate Dehydrogenase Deficiency",
        "Leber Congenital Amaurosis 2",
        "Dravet Syndrome",
        "Mucopolysaccharidosis Type 3 A",
        "Ornithine Translocase Deficiency",
        "Carnitine-acylcarnitine Translocase Deficiency",
        "Glucose Transporter Type 1 Deficiency Syndrome",
        "Creatine Transporter Deficiency",
        "Niemann-Pick Disease Type A",
        "Pitt Hopkins Syndrome",
        "Tuberous Sclerosis 1",
        "Tuberous Sclerosis 2",
        "Ataxia With Isolated Vitamin E Deficiency",
        "Angelman Syndrome",
        "Prader-Willi Syndrome",
        "Homocystinuria",
        "Permanent Neonatal Diabetes Mellitus",
        "Transient Neonatal Diabetes Mellitus",
        "Factor VII Deficiency",
        "Glycogen Storage Disease Type IXA1",
        "Glycogen Storage Disease, Type IXA2",
        "Glycogen Storage Disease IC",
        "Glycogen Storage Disease Type IB",
        "Central Hypoventilation Syndrome With or Without Hirschsprung Disease"
      ],
      "interventions": [
        {
          "name": "Confirmatory Testing",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "RTI International",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "31 Days",
        "sex": "ALL",
        "summary": "1 Day to 31 Days"
      },
      "enrollment_count": 30000,
      "start_date": "2018-10-15",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-01",
      "last_synced_at": "2026-11-05T15:49:28.811Z",
      "location_count": 1,
      "location_summary": "Research Triangle Park, North Carolina",
      "locations": [
        {
          "city": "Research Triangle Park",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03655223"
    },
    {
      "nct_id": "NCT06864260",
      "title": "Cancer PRevention Through Enhanced EnvironMenT",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cancer Risk"
      ],
      "interventions": [
        {
          "name": "Built Environment",
          "type": "OTHER"
        },
        {
          "name": "Social Environment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2024-05-01",
      "completion_date": "2028-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-11",
      "last_synced_at": "2026-11-05T15:49:28.811Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06864260"
    },
    {
      "nct_id": "NCT02524197",
      "title": "A Study of the Safety and Effectiveness of Orally Administered CR845 in Patients With Osteoarthritis of the Hip or Knee",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "CR845 0.25 mg",
          "type": "DRUG"
        },
        {
          "name": "CR845 0.50 mg",
          "type": "DRUG"
        },
        {
          "name": "CR845 1 mg",
          "type": "DRUG"
        },
        {
          "name": "CR845 5 mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cara Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "25 Years and older"
      },
      "enrollment_count": 81,
      "start_date": "2015-08",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2017-01-31",
      "last_synced_at": "2026-11-05T15:49:28.811Z",
      "location_count": 5,
      "location_summary": "Omaha, Nebraska • Las Vegas, Nevada • Greensboro, North Carolina + 2 more",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        },
        {
          "city": "Las Vegas",
          "state": "Nevada"
        },
        {
          "city": "Greensboro",
          "state": "North Carolina"
        },
        {
          "city": "Duncansville",
          "state": "Pennsylvania"
        },
        {
          "city": "Plano",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02524197"
    },
    {
      "nct_id": "NCT04188873",
      "title": "Cessation Screening Project",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Preparation Varenicline and Standard Duration Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Preparation Varenicline and Extended Duration Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Standard Duration Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Extended Duration Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Preparation Combination NRT and Standard Duration Combination NRT",
          "type": "DRUG"
        },
        {
          "name": "Preparation Combination NRT and Extended Duration Combination NRT",
          "type": "DRUG"
        },
        {
          "name": "Standard Duration Combination NRT",
          "type": "DRUG"
        },
        {
          "name": "Extended Duration Combination NRT",
          "type": "DRUG"
        },
        {
          "name": "Intensive Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Minimal Counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 538,
      "start_date": "2020-12-10",
      "completion_date": "2025-05-08",
      "has_results": true,
      "last_update_posted_date": "2026-06-17",
      "last_synced_at": "2026-11-05T15:49:28.811Z",
      "location_count": 2,
      "location_summary": "Madison, Wisconsin • Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04188873"
    },
    {
      "nct_id": "NCT01897896",
      "title": "Alternatives for Reducing Chorea in Huntington Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Chorea Associated With Huntington Disease"
      ],
      "interventions": [
        {
          "name": "SD-809",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Auspex Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 119,
      "start_date": "2013-11-12",
      "completion_date": "2017-08-21",
      "has_results": true,
      "last_update_posted_date": "2021-11-09",
      "last_synced_at": "2026-11-05T15:49:28.811Z",
      "location_count": 34,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Fayetteville, Arkansas + 30 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Fayetteville",
          "state": "Arkansas"
        },
        {
          "city": "Englewood",
          "state": "Colorado"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01897896"
    },
    {
      "nct_id": "NCT04259762",
      "title": "Enhancing Cancer Prevention and Control Pathways-Native Health Initiative",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cancer, Breast",
        "Cancer, Colon",
        "Cancer, Cervix"
      ],
      "interventions": [
        {
          "name": "Aim 8 (INT, Pilot Test): Breast, Colorectal, and Cervical Cancer Screening Cognitive-Behavioral Interventions",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "New Mexico Cancer Research Alliance",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 508,
      "start_date": "2021-06-01",
      "completion_date": "2023-10-31",
      "has_results": true,
      "last_update_posted_date": "2025-09-24",
      "last_synced_at": "2026-11-05T15:49:28.811Z",
      "location_count": 1,
      "location_summary": "Albuquerque, New Mexico",
      "locations": [
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04259762"
    },
    {
      "nct_id": "NCT03375320",
      "title": "Testing Cabozantinib in Patients With Advanced Pancreatic Neuroendocrine and Carcinoid Tumors",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Functioning Pancreatic Neuroendocrine Tumor",
        "Intermediate Grade Lung Neuroendocrine Neoplasm",
        "Locally Advanced Digestive System Neuroendocrine Neoplasm",
        "Locally Advanced Digestive System Neuroendocrine Tumor G1",
        "Locally Advanced Lung Neuroendocrine Neoplasm",
        "Locally Advanced Pancreatic Neuroendocrine Tumor",
        "Locally Advanced Unresectable Digestive System Neuroendocrine Neoplasm",
        "Low Grade Lung Neuroendocrine Neoplasm",
        "Lung Neuroendocrine Tumor",
        "Lung Neuroendocrine Tumor G2",
        "Metastatic Digestive System Neuroendocrine Neoplasm",
        "Metastatic Digestive System Neuroendocrine Tumor G1",
        "Metastatic Lung Neuroendocrine Neoplasm",
        "Metastatic Lung Neuroendocrine Tumor",
        "Metastatic Pancreatic Neuroendocrine Neoplasm",
        "Metastatic Pancreatic Neuroendocrine Tumor",
        "Metastatic Thymus Neuroendocrine Neoplasm",
        "Neuroendocrine Neoplasm",
        "Neuroendocrine Tumor",
        "Neuroendocrine Tumor G2",
        "Non-Functioning Pancreatic Neuroendocrine Tumor",
        "Pancreatic Serotonin-Producing Neuroendocrine Tumor",
        "Thymus Neuroendocrine Tumor",
        "Unresectable Digestive System Neuroendocrine Neoplasm",
        "Unresectable Digestive System Neuroendocrine Tumor G1",
        "Unresectable Lung Neuroendocrine Neoplasm",
        "Unresectable Pancreatic Neuroendocrine Neoplasm",
        "Unresectable Thymus Neuroendocrine Neoplasm"
      ],
      "interventions": [
        {
          "name": "Biospecimen Collection",
          "type": "PROCEDURE"
        },
        {
          "name": "Cabozantinib S-malate",
          "type": "DRUG"
        },
        {
          "name": "Computed Tomography",
          "type": "PROCEDURE"
        },
        {
          "name": "Magnetic Resonance Imaging",
          "type": "PROCEDURE"
        },
        {
          "name": "Placebo Administration",
          "type": "OTHER"
        },
        {
          "name": "Quality-of-Life Assessment",
          "type": "OTHER"
        },
        {
          "name": "X-Ray Imaging",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 298,
      "start_date": "2018-10-26",
      "completion_date": "2027-09-01",
      "has_results": true,
      "last_update_posted_date": "2026-10-26",
      "last_synced_at": "2026-11-05T15:49:28.811Z",
      "location_count": 432,
      "location_summary": "Anchorage, Alaska • Kingman, Arizona • Phoenix, Arizona + 289 more",
      "locations": [
        {
          "city": "Anchorage",
          "state": "Alaska"
        },
        {
          "city": "Kingman",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03375320"
    },
    {
      "nct_id": "NCT02100189",
      "title": "Esophageal Cytology With FISH in Detecting Esophageal Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dysphagia",
        "Dysplasia",
        "Esophageal Adenocarcinoma",
        "Esophageal Squamous Cell Carcinoma",
        "Esophagitis",
        "Gastroesophageal Reflux Disease",
        "High Grade Dysplasia in Barrett Esophagus",
        "Weight Loss"
      ],
      "interventions": [
        {
          "name": "Cytology Specimen Collection Procedure",
          "type": "OTHER"
        },
        {
          "name": "Esophagogastroduodenoscopy",
          "type": "PROCEDURE"
        },
        {
          "name": "Laboratory Biomarker Analysis",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "OHSU Knight Cancer Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2014-02",
      "completion_date": "2015-12",
      "has_results": true,
      "last_update_posted_date": "2017-05-11",
      "last_synced_at": "2026-11-05T15:49:28.811Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02100189"
    }
  ]
}