{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Premenstrual+Syndrome+Supplement",
    "query": {
      "intervention": "Premenstrual Syndrome Supplement"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 9,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-27T16:51:07.277Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06136104",
      "title": "The Effects of Mixhers HERTIME Supplements on Menstrual Symptoms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy",
        "Premenstrual Dysphoric Disorder",
        "Premenstrual Syndrome"
      ],
      "interventions": [
        {
          "name": "Mixhers HERTIME",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Midwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 100,
      "start_date": "2023-08-30",
      "completion_date": "2023-12-20",
      "has_results": false,
      "last_update_posted_date": "2024-05-08",
      "last_synced_at": "2026-09-27T16:51:07.277Z",
      "location_count": 1,
      "location_summary": "Glendale, Arizona",
      "locations": [
        {
          "city": "Glendale",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06136104"
    },
    {
      "nct_id": "NCT07018479",
      "title": "Effects of a Female Hormone Balance Supplement on Premenstrual Syndrome Symptoms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premenstrual Syndrome"
      ],
      "interventions": [
        {
          "name": "FemmeBalance Supplement Group",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "VINABAS FORMULATIONS SL",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 38,
      "start_date": "2024-07-30",
      "completion_date": "2025-01-20",
      "has_results": false,
      "last_update_posted_date": "2025-06-12",
      "last_synced_at": "2026-09-27T16:51:07.277Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07018479"
    },
    {
      "nct_id": "NCT04005456",
      "title": "Personalized Lifestyle Intervention for Improving Functional Health Outcomes Using N-of-1 Tent-Umbrella-Bucket Design",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Health, Subjective",
        "Gastrointestinal Dysfunction",
        "Cardiovascular Risk Factor",
        "Autoimmune Diseases",
        "Dental Diseases",
        "Hormone Disturbance",
        "Neurocognitive Dysfunction"
      ],
      "interventions": [
        {
          "name": "Supplements and/or medical foods",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Behavioral change support program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Food plan",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Metagenics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 400,
      "start_date": "2018-09-01",
      "completion_date": "2022-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-10-30",
      "last_synced_at": "2026-09-27T16:51:07.277Z",
      "location_count": 1,
      "location_summary": "Gig Harbor, Washington",
      "locations": [
        {
          "city": "Gig Harbor",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04005456"
    },
    {
      "nct_id": "NCT07441096",
      "title": "Efficacy and Safety of Shatavari Root Extract for Premenstrual Syndrome in Women",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premenstrual Syndrome",
        "Women Health"
      ],
      "interventions": [
        {
          "name": "Shatavari Root Extract",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo Capsule",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "SF Research Institute, Inc.",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2026-03-20",
      "completion_date": "2026-07-08",
      "has_results": false,
      "last_update_posted_date": "2026-03-03",
      "last_synced_at": "2026-09-27T16:51:07.277Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07441096"
    },
    {
      "nct_id": "NCT06763809",
      "title": "A Randomized Placebo-Controlled Study to Evaluate the Effects of a Gummy and Capsule Supplement on Symptoms of Premenstrual Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "PMS",
        "Menstrual Cramp",
        "Mood Change"
      ],
      "interventions": [
        {
          "name": "PMS Capsule",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Capsule Placebo",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "PMS Gummy",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Gummy Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Semaine Health",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 176,
      "start_date": "2024-09-04",
      "completion_date": "2024-12-12",
      "has_results": false,
      "last_update_posted_date": "2025-01-08",
      "last_synced_at": "2026-09-27T16:51:07.277Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06763809"
    },
    {
      "nct_id": "NCT06124326",
      "title": "A Single Group Study to Evaluate the Effects of a Supplement on Premenstrual Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premenstrual Syndrome"
      ],
      "interventions": [
        {
          "name": "Premenstrual Syndrome Supplement",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Rael",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 40,
      "start_date": "2023-08-31",
      "completion_date": "2024-01-20",
      "has_results": false,
      "last_update_posted_date": "2024-08-23",
      "last_synced_at": "2026-09-27T16:51:07.277Z",
      "location_count": 1,
      "location_summary": "Santa Monica, California",
      "locations": [
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06124326"
    },
    {
      "nct_id": "NCT05237661",
      "title": "Study to Evaluate Your Super's Moon Balance and Its Impact on Premenstrual Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "PMS",
        "Menstrual Discomfort",
        "Menstrual Pain"
      ],
      "interventions": [
        {
          "name": "Moon Balance",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Your Super, INC.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 38,
      "start_date": "2022-02-15",
      "completion_date": "2022-05-31",
      "has_results": false,
      "last_update_posted_date": "2022-06-21",
      "last_synced_at": "2026-09-27T16:51:07.277Z",
      "location_count": 1,
      "location_summary": "Santa Monica, California",
      "locations": [
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05237661"
    },
    {
      "nct_id": "NCT04123483",
      "title": "EnBrace HR for PMS With Prominent Mood Symptoms or Menstrual Related Mood Disorders",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Premenstrual Syndrome",
        "Premenstrual Dysphoric Disorder",
        "Premenstrual Tension",
        "Menstrual Related Mood Disorder"
      ],
      "interventions": [
        {
          "name": "EnBrace HR Softgel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "52 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 52 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2019-11",
      "completion_date": "2022-11",
      "has_results": false,
      "last_update_posted_date": "2020-01-02",
      "last_synced_at": "2026-09-27T16:51:07.277Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04123483"
    },
    {
      "nct_id": "NCT06124300",
      "title": "Effects of a Female Hormone Balance Supplement on Symptoms of Polycystic Ovary Syndrome and Severe Premenstrual Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Polycystic Ovary Syndrome",
        "Premenstrual Syndrome"
      ],
      "interventions": [
        {
          "name": "Female Hormone Balance Supplement",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Rael",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 55 Years · Female only"
      },
      "enrollment_count": 40,
      "start_date": "2023-08-30",
      "completion_date": "2024-01-19",
      "has_results": false,
      "last_update_posted_date": "2024-08-23",
      "last_synced_at": "2026-09-27T16:51:07.277Z",
      "location_count": 1,
      "location_summary": "Santa Monica, California",
      "locations": [
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06124300"
    }
  ]
}