{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pressure+Controlled+Mode&page=2",
    "query": {
      "intervention": "Pressure Controlled Mode",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pressure+Controlled+Mode&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-16T02:33:16.825Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02680704",
      "title": "Mechanical Ventilation in Severe Brain Injury: The Effect of Positive End Expiratory Pressure on Intracranial Pressure",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intracranial Hypertension",
        "Critical Illness",
        "Brain Injuries",
        "Lung Injury",
        "Respiratory Failure",
        "Positive-Pressure Respiration, Intrinsic"
      ],
      "interventions": [
        {
          "name": "PEEP titrated mechanical ventilation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Beth Israel Deaconess Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "2016-02",
      "completion_date": "2018-08-02",
      "has_results": false,
      "last_update_posted_date": "2019-02-22",
      "last_synced_at": "2026-09-16T02:33:16.825Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02680704"
    },
    {
      "nct_id": "NCT02158923",
      "title": "Individualized Perioperative Open Lung Ventilatory Strategy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Moderated-high Risk of Postoperative Pulmonary Complication",
        "Abdominal Surgery Expected More Than Two Hours"
      ],
      "interventions": [
        {
          "name": "Alveolar recruitment maneuver",
          "type": "PROCEDURE"
        },
        {
          "name": "Calculation of optimal PEEP",
          "type": "PROCEDURE"
        },
        {
          "name": "Postoperative CPAP",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Fundación para la Investigación del Hospital Clínico de Valencia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 920,
      "start_date": "2014-09",
      "completion_date": "2016-04",
      "has_results": false,
      "last_update_posted_date": "2016-05-17",
      "last_synced_at": "2026-09-16T02:33:16.825Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02158923"
    },
    {
      "nct_id": "NCT01368614",
      "title": "AVAPS-AE Efficacy Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity Hypoventilation Syndrome"
      ],
      "interventions": [
        {
          "name": "AVAPS-AE Mode of Therapy",
          "type": "DEVICE"
        },
        {
          "name": "Respironics OnmiLab BiPAP S mode",
          "type": "DEVICE"
        },
        {
          "name": "Respironics OmniLab Advanced CPAP mode",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Philips Respironics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 90,
      "start_date": "2011-09-12",
      "completion_date": "2013-05-30",
      "has_results": true,
      "last_update_posted_date": "2019-04-26",
      "last_synced_at": "2026-09-16T02:33:16.825Z",
      "location_count": 2,
      "location_summary": "Tucson, Arizona • Chicago, Illinois",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01368614"
    },
    {
      "nct_id": "NCT06624254",
      "title": "Ventilator Mode and Respiratory Physiology",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pulmonary Disease",
        "Respiratory Failure",
        "Respiratory Effort",
        "Breathing Mechanics"
      ],
      "interventions": [
        {
          "name": "lung mechanics, respiratory drive and effort",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2024-09-21",
      "completion_date": "2029-09",
      "has_results": false,
      "last_update_posted_date": "2024-10-02",
      "last_synced_at": "2026-09-16T02:33:16.825Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06624254"
    },
    {
      "nct_id": "NCT07656259",
      "title": "COMPARE-VENT Feasibility Pilot Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiration Failure",
        "Cardio Vascular Disease",
        "Cardiogenic Pulmonary Oedema",
        "Critical Illness",
        "Mechanical Ventilation",
        "Cardiogenic Shock",
        "Cardiopulmonary"
      ],
      "interventions": [
        {
          "name": "Volume Controlled Mode",
          "type": "OTHER"
        },
        {
          "name": "Pressure Controlled Mode",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 75,
      "start_date": "2026-07-01",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-10",
      "last_synced_at": "2026-09-16T02:33:16.825Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07656259"
    },
    {
      "nct_id": "NCT07123961",
      "title": "Pediatric Acute Respiratory Distress Syndrome (ARDS) Management Trial",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Respiratory Distress Syndrome (ARDS)",
        "Ventilator Management",
        "Lung-protective Ventilation",
        "Pediatric Acute Respiratory Distress Syndrome (PARDS)"
      ],
      "interventions": [
        {
          "name": "High Driving Pressure Mechanical Ventilation",
          "type": "OTHER"
        },
        {
          "name": "Low Driving Pressure Mechanical Ventilation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Weeks",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "2 Weeks to 17 Years"
      },
      "enrollment_count": 160,
      "start_date": "2025-11-07",
      "completion_date": "2030-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-14",
      "last_synced_at": "2026-09-16T02:33:16.825Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07123961"
    },
    {
      "nct_id": "NCT07313956",
      "title": "Mode of Ventilation During Critical Illness at Multiple Centers",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Failure",
        "Mechanical Ventilation",
        "Critical Illness"
      ],
      "interventions": [
        {
          "name": "Volume control",
          "type": "OTHER"
        },
        {
          "name": "Pressure control",
          "type": "OTHER"
        },
        {
          "name": "Adaptive pressure control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4785,
      "start_date": "2026-05-01",
      "completion_date": "2030-03",
      "has_results": false,
      "last_update_posted_date": "2026-08-28",
      "last_synced_at": "2026-09-16T02:33:16.825Z",
      "location_count": 4,
      "location_summary": "Chicago, Illinois • Baltimore, Maryland • Winston-Salem, North Carolina + 1 more",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07313956"
    },
    {
      "nct_id": "NCT06063122",
      "title": "Development of a Therapeutic Device to Improve Speech Sound Differentiation in Preterm Infants",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premature Birth"
      ],
      "interventions": [
        {
          "name": "smallTalk NICU Active",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Thrive Neuromedical, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "32 Weeks",
        "maximum_age": "35 Weeks",
        "sex": "ALL",
        "summary": "32 Weeks to 35 Weeks"
      },
      "enrollment_count": 203,
      "start_date": "2024-03-08",
      "completion_date": "2026-02-01",
      "has_results": false,
      "last_update_posted_date": "2025-09-10",
      "last_synced_at": "2026-09-16T02:33:16.825Z",
      "location_count": 2,
      "location_summary": "Atlanta, Georgia • Chagrin Falls, Ohio",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chagrin Falls",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06063122"
    },
    {
      "nct_id": "NCT04584762",
      "title": "Automated Variable Pattern Insufflator Device (AVPI) for the Acute Treatment of Migraine",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Migraine Headache"
      ],
      "interventions": [
        {
          "name": "Automated Variable Pressure Insufflation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Nocira, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2020-03-09",
      "completion_date": "2022-10-31",
      "has_results": false,
      "last_update_posted_date": "2022-09-10",
      "last_synced_at": "2026-09-16T02:33:16.825Z",
      "location_count": 3,
      "location_summary": "Scottsdale, Arizona • St. Petersburg, Florida • Saint Charles, Missouri",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "St. Petersburg",
          "state": "Florida"
        },
        {
          "city": "Saint Charles",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04584762"
    },
    {
      "nct_id": "NCT06849596",
      "title": "Manual T-piece Versus Ventilator Positive Pressure Ventilation During Resuscitation of Extremely Premature Neonates",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neonatal Resuscitation",
        "Apnea Neonatal"
      ],
      "interventions": [
        {
          "name": "Ventilator derived positive pressure ventilation - V-PPV",
          "type": "DEVICE"
        },
        {
          "name": "T-piece resuscitator (TPR)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Michelle Baczynski",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Weeks",
        "maximum_age": "29 Weeks",
        "sex": "ALL",
        "summary": "25 Weeks to 29 Weeks"
      },
      "enrollment_count": 780,
      "start_date": "2025-12-01",
      "completion_date": "2029-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-06-11",
      "last_synced_at": "2026-09-16T02:33:16.825Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06849596"
    }
  ]
}