{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Primary+Knee+implants&page=2",
    "query": {
      "intervention": "Primary Knee implants",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Primary+Knee+implants&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-27T13:36:14.365Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04301622",
      "title": "Post Market Clinical Follow-Up Study for EVOLUTION® BIOFOAM® Tibia and EVOLUTION® CS/CR Porous Femur",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Knee Osteoarthritis",
        "Traumatic Arthritis of Knee",
        "Avascular Necrosis",
        "Degenerative Joint Disease of Knee",
        "Rheumatoid Arthritis of Knee",
        "Correction of Functional Deformity"
      ],
      "interventions": [
        {
          "name": "Primary Knee implants",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "MicroPort Orthopedics Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2020-02-03",
      "completion_date": "2032-08",
      "has_results": false,
      "last_update_posted_date": "2024-03-20",
      "last_synced_at": "2026-09-27T13:36:14.365Z",
      "location_count": 1,
      "location_summary": "Saginaw, Michigan",
      "locations": [
        {
          "city": "Saginaw",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04301622"
    },
    {
      "nct_id": "NCT06089291",
      "title": "Persona IQ Cohort Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteo Arthritis Knee",
        "Knee Arthritis",
        "Monitoring Orthopedic Devices",
        "Total Knee Arthroplasty",
        "Total Knee Replacement"
      ],
      "interventions": [
        {
          "name": "Persona IQ",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2024-02-20",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-04",
      "last_synced_at": "2026-09-27T13:36:14.365Z",
      "location_count": 4,
      "location_summary": "Granger, Indiana • St Louis, Missouri • Charlotte, North Carolina + 1 more",
      "locations": [
        {
          "city": "Granger",
          "state": "Indiana"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06089291"
    },
    {
      "nct_id": "NCT04821154",
      "title": "Persona Revision Knee System Outcomes",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Arthroplasty Complications",
        "Infection",
        "Knee Disease",
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Persona Revision Knee System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 380,
      "start_date": "2021-06-14",
      "completion_date": "2033-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-10",
      "last_synced_at": "2026-09-27T13:36:14.365Z",
      "location_count": 16,
      "location_summary": "Fayetteville, Arkansas • Little Rock, Arkansas • Fresno, California + 13 more",
      "locations": [
        {
          "city": "Fayetteville",
          "state": "Arkansas"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Superior",
          "state": "Colorado"
        },
        {
          "city": "Evansville",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04821154"
    },
    {
      "nct_id": "NCT04670042",
      "title": "Using Peripheral Nerve Stimulation (PNS) to Treat Chronic Post-surgical Pain (CPSP) After Knee Surgery",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Injury; Nerve, Peripheral, Multiple",
        "Chronic Post-Procedural Pain",
        "Total Knee Arthroplasty",
        "Surgery",
        "Knee Injuries",
        "Knee Pain Chronic",
        "Postoperative Pain",
        "Chronic Postoperative Pain"
      ],
      "interventions": [
        {
          "name": "SPRINT® Peripheral Nerve Stimulation (PNS) System (510k Cleared)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2021-06-25",
      "completion_date": "2024-05",
      "has_results": false,
      "last_update_posted_date": "2022-10-20",
      "last_synced_at": "2026-09-27T13:36:14.365Z",
      "location_count": 1,
      "location_summary": "Redwood City, California",
      "locations": [
        {
          "city": "Redwood City",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04670042"
    },
    {
      "nct_id": "NCT02286739",
      "title": "Prospective Clinical Study Evaluating Tibiofemoral Rotational Alignment Using Intraoperative Sensing During Total Knee Arthroplasty (TKA)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "TKA with \"Verasense\"",
          "type": "DEVICE"
        },
        {
          "name": "TKA without \"Verasense\"",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Orthosensor, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2015-04",
      "completion_date": "2020-05",
      "has_results": true,
      "last_update_posted_date": "2024-08-19",
      "last_synced_at": "2026-09-27T13:36:14.365Z",
      "location_count": 6,
      "location_summary": "Weston, Florida • Atlanta, Georgia • Morton Grove, Illinois + 3 more",
      "locations": [
        {
          "city": "Weston",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Morton Grove",
          "state": "Illinois"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02286739"
    },
    {
      "nct_id": "NCT05082831",
      "title": "Human ECM Implanted Within Microfracture Interstices & the Cartilage Defect in the Knee to Regenerate Hyaline Cartilage",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Articular Cartilage Disorder of Knee",
        "Cartilage Damage",
        "Microfractures"
      ],
      "interventions": [
        {
          "name": "microfracture surgery + HST003",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Histogen",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 1,
      "start_date": "2021-11-15",
      "completion_date": "2023-01-16",
      "has_results": false,
      "last_update_posted_date": "2023-01-19",
      "last_synced_at": "2026-09-27T13:36:14.365Z",
      "location_count": 5,
      "location_summary": "Vail, Colorado • Bradenton, Florida • Bethesda, Maryland + 2 more",
      "locations": [
        {
          "city": "Vail",
          "state": "Colorado"
        },
        {
          "city": "Bradenton",
          "state": "Florida"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "State College",
          "state": "Pennsylvania"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05082831"
    },
    {
      "nct_id": "NCT00289107",
      "title": "Randomized Fixed Bearing vs Mobile Bearing Cruciate Substituting TKA",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis",
        "Rheumatoid Arthritis",
        "Other Inflammatory Arthritis",
        "Post-Traumatic Arthritis",
        "Juvenile Rheumatoid Arthritis",
        "Avascular Necrosis"
      ],
      "interventions": [
        {
          "name": "Total Knee Arthroplasty",
          "type": "DEVICE"
        },
        {
          "name": "Total knee replacement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DePuy Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 149,
      "start_date": "2001-04-01",
      "completion_date": "2007-11-01",
      "has_results": true,
      "last_update_posted_date": "2023-05-03",
      "last_synced_at": "2026-09-27T13:36:14.365Z",
      "location_count": 3,
      "location_summary": "Greensboro, North Carolina • Austin, Texas • Lakewood, Washington",
      "locations": [
        {
          "city": "Greensboro",
          "state": "North Carolina"
        },
        {
          "city": "Austin",
          "state": "Texas"
        },
        {
          "city": "Lakewood",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00289107"
    },
    {
      "nct_id": "NCT04145401",
      "title": "Post Market Clinical Follow-Up Study- EVOLUTION® Revision CCK",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Revision Knee implants",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "MicroPort Orthopedics Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2020-09-30",
      "completion_date": "2033-11-01",
      "has_results": false,
      "last_update_posted_date": "2024-03-20",
      "last_synced_at": "2026-09-27T13:36:14.365Z",
      "location_count": 1,
      "location_summary": "Englewood, Colorado",
      "locations": [
        {
          "city": "Englewood",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04145401"
    },
    {
      "nct_id": "NCT04730271",
      "title": "Comparison of Alignment Achieved Using the VELYS Robotic-Assisted Solution Versus Manual Instrumentation in Total Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteo Arthritis Knee",
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Total Knee Replacement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DePuy Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "22 Years to 85 Years"
      },
      "enrollment_count": 200,
      "start_date": "2021-02-23",
      "completion_date": "2023-09-06",
      "has_results": true,
      "last_update_posted_date": "2025-04-27",
      "last_synced_at": "2026-09-27T13:36:14.365Z",
      "location_count": 5,
      "location_summary": "Baltimore, Maryland • Crosby, Minnesota • Charlotte, North Carolina + 2 more",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Crosby",
          "state": "Minnesota"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Germantown",
          "state": "Tennessee"
        },
        {
          "city": "Renton",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04730271"
    },
    {
      "nct_id": "NCT05629715",
      "title": "Conventional Instrumentation, Computer Navigation, and Robotic Assistance Techniques in TKA",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "ROSA Knee System",
          "type": "DEVICE"
        },
        {
          "name": "KneeAlign Computer Assisted Navigation System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2025-06-01",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2024-08-13",
      "last_synced_at": "2026-09-27T13:36:14.365Z",
      "location_count": 1,
      "location_summary": "Santa Monica, California",
      "locations": [
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05629715"
    }
  ]
}