{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Primary+Local+Therapy",
    "query": {
      "intervention": "Primary Local Therapy"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 224,
    "total_pages": 23,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Primary+Local+Therapy&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T21:38:25.205Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06855732",
      "title": "Pain Self-Management and Treatment Engagement for Patients Taking Opioids",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Pain",
        "Opioid Use Disorder",
        "Opioid Misuse and Addiction"
      ],
      "interventions": [
        {
          "name": "Usual Care",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pain Self-Management",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 204,
      "start_date": "2024-11-25",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-18",
      "last_synced_at": "2026-09-03T21:38:25.205Z",
      "location_count": 17,
      "location_summary": "Baltimore, Maryland • Allison Park, Pennsylvania • Blawnox, Pennsylvania + 9 more",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Allison Park",
          "state": "Pennsylvania"
        },
        {
          "city": "Blawnox",
          "state": "Pennsylvania"
        },
        {
          "city": "Glenshaw",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06855732"
    },
    {
      "nct_id": "NCT00254852",
      "title": "Evaluation of Radiographic and Patient Outcomes Following Lumbar Spine Fusion Using Demineralized Bone Matrix (DBM) Mixed With Autograft",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stenosis",
        "Spondylolisthesis",
        "Degenerative Disc Disease"
      ],
      "interventions": [
        {
          "name": "Posterior Lateral Fusion (PLF)",
          "type": "PROCEDURE"
        },
        {
          "name": "Anterior Lumbar Interbody Fusion (ALIF)",
          "type": "PROCEDURE"
        },
        {
          "name": "Transforaminal lumbar interbody fusion (TLIF)",
          "type": "PROCEDURE"
        },
        {
          "name": "Posterior lumbar interbody fusion (PLIF)",
          "type": "PROCEDURE"
        },
        {
          "name": "Extreme lateral interbody fusion (XLIF)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Exactech",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 94,
      "start_date": "2005-10",
      "completion_date": "2011-08",
      "has_results": false,
      "last_update_posted_date": "2013-11-21",
      "last_synced_at": "2026-09-03T21:38:25.205Z",
      "location_count": 6,
      "location_summary": "Long Beach, California • San Diego, California • New Hartford, New York + 3 more",
      "locations": [
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "New Hartford",
          "state": "New York"
        },
        {
          "city": "Syracuse",
          "state": "New York"
        },
        {
          "city": "Bristol",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00254852"
    },
    {
      "nct_id": "NCT05085886",
      "title": "Implementation Science Approach to Enhancing Depression Treatment in Collaborative Depression Care Settings ( DepCare )",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depressive Symptoms"
      ],
      "interventions": [
        {
          "name": "DepCare",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced Usual Care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 605,
      "start_date": "2021-08-03",
      "completion_date": "2023-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-02-14",
      "last_synced_at": "2026-09-03T21:38:25.205Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05085886"
    },
    {
      "nct_id": "NCT02942979",
      "title": "Maintaining Independence and Sobriety Through Systems Integration, Outreach, and Networking",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Co-Occurring Disorders",
        "Homelessness",
        "Substance Abuse Disorder",
        "Mental Illness"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 108,
      "start_date": "2016-02-12",
      "completion_date": "2020-09-01",
      "has_results": true,
      "last_update_posted_date": "2023-07-21",
      "last_synced_at": "2026-09-03T21:38:25.205Z",
      "location_count": 1,
      "location_summary": "Bedford, Massachusetts",
      "locations": [
        {
          "city": "Bedford",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02942979"
    },
    {
      "nct_id": "NCT01451879",
      "title": "Observational Study for Subjects With Pompe Disease Undergoing Immune Modulation Therapies",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pompe Disease"
      ],
      "interventions": [
        {
          "name": "Rituximab",
          "type": "DRUG"
        },
        {
          "name": "Miglustat",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "Up to 65 Years"
      },
      "enrollment_count": 11,
      "start_date": "2008-10",
      "completion_date": "2017-10",
      "has_results": false,
      "last_update_posted_date": "2017-12-08",
      "last_synced_at": "2026-09-03T21:38:25.205Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01451879"
    },
    {
      "nct_id": "NCT07290361",
      "title": "Stratified Targeted Engagement From Primary Care to Physical Therapy (STEPPT)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain",
        "Neck Pain"
      ],
      "interventions": [
        {
          "name": "Engagement of clinic leadership (System Intervention - Usual Care)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Engagement of clinic leadership (System Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Registry (System Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Delivery of Patient Education Materials (System Intervention - Usual Care)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Delivery of Patient Education Materials (System Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Referral Specialist Training (System Intervention - Usual Care)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Health Navigator Training (System Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Care Navigation (System Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Care navigation audit and feedback (System Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Primary Care Provider training (Provider Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nurse/Medical Assistant Training (Provider Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Provider feedback on PT referral and adherence (Provider Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient education on spine pain condition (Patient Intervention - Usual Care)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient education on spine pain condition (Patient Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Education on Physical Referral by Providers (Patient Intervention - Usual Care)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Education on Physical Referral by Providers (Patient Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Electronic Patient Education on Physical Therapy Referral (Patient Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient education on physical therapy referral by Referral Specialist (Patient Intervention - Usual Care)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient education on physical therapy referral by Patient Health Navigator (Patient Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Care Navigation (System Intervention - Usual Care)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Monitoring of PT referral and adherence rates (System Intervention - STEPPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Monitoring of PT referral and adherence rates (System intervention - Usual Care)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "San Diego State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 17587,
      "start_date": "2025-12-01",
      "completion_date": "2029-02-28",
      "has_results": false,
      "last_update_posted_date": "2026-08-14",
      "last_synced_at": "2026-09-03T21:38:25.205Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07290361"
    },
    {
      "nct_id": "NCT04798521",
      "title": "TeleHepC Treatment Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hepatitis C"
      ],
      "interventions": [
        {
          "name": "Tele-HCV",
          "type": "OTHER"
        },
        {
          "name": "Community Linkage to Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 203,
      "start_date": "2020-06-30",
      "completion_date": "2024-01-10",
      "has_results": true,
      "last_update_posted_date": "2024-10-08",
      "last_synced_at": "2026-09-03T21:38:25.205Z",
      "location_count": 3,
      "location_summary": "Portland, Oregon • Roseburg, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Roseburg",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04798521"
    },
    {
      "nct_id": "NCT03808675",
      "title": "Aerobic Exercise in Parkinson's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson's Disease"
      ],
      "interventions": [
        {
          "name": "Aerobic walking",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual care with PD specific health education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 57,
      "start_date": "2019-07-01",
      "completion_date": "2024-09-30",
      "has_results": true,
      "last_update_posted_date": "2026-03-12",
      "last_synced_at": "2026-09-03T21:38:25.205Z",
      "location_count": 2,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03808675"
    },
    {
      "nct_id": "NCT01650844",
      "title": "School-Based Telemedicine Enhanced Asthma Management",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pediatric Asthma"
      ],
      "interventions": [
        {
          "name": "School-Based Telemedicine Enhanced Asthma Management",
          "type": "OTHER"
        },
        {
          "name": "Enhanced Usual Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "10 Years",
        "sex": "ALL",
        "summary": "3 Years to 10 Years"
      },
      "enrollment_count": 400,
      "start_date": "2012-08",
      "completion_date": "2018-07",
      "has_results": true,
      "last_update_posted_date": "2018-09-28",
      "last_synced_at": "2026-09-03T21:38:25.205Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01650844"
    },
    {
      "nct_id": "NCT06044831",
      "title": "Expanded Population Health Model Evaluation",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Disease",
        "Quality of Life"
      ],
      "interventions": [
        {
          "name": "Expanded Population Health Model",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Baylor Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2023-08-28",
      "completion_date": "2026-10",
      "has_results": false,
      "last_update_posted_date": "2026-04-09",
      "last_synced_at": "2026-09-03T21:38:25.205Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06044831"
    }
  ]
}