{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Probe+drugs", "query": { "intervention": "Probe drugs" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 151, "total_pages": 16, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Probe+drugs&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-04T16:23:59.461Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01596647", "title": "Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid Tumors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Advanced Solid Tumors, Excluding Breast Cancer" ], "interventions": [ { "name": "caffeine", "type": "DRUG" }, { "name": "diclofenac", "type": "DRUG" }, { "name": "omeprazole", "type": "DRUG" }, { "name": "midazolam", "type": "DRUG" }, { "name": "TKI258", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 39, "start_date": "2012-05", "completion_date": "2014-07", "has_results": false, "last_update_posted_date": "2020-12-21", "last_synced_at": "2026-09-04T16:23:59.461Z", "location_count": 5, "location_summary": "Kansas City, Kansas • Detroit, Michigan • Minneapolis, Minnesota + 2 more", "locations": [ { "city": "Kansas City", "state": "Kansas" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Minneapolis", "state": "Minnesota" }, { "city": "Las Vegas", "state": "Nevada" }, { "city": "New Brunswick", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT01596647" }, { "nct_id": "NCT04440475", "title": "Tap Block vs Conventional Pain Medication for Patients Undergoing Robotic Sacrocolpopexy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Anesthesia, Local", "Prolapse", "Prolapse; Female", "Prolapse, Vaginal", "Prolapse; Vagina, Posthysterectomy", "Pain, Postoperative" ], "interventions": [ { "name": "TAP block", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "ProMedica Health System", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 40, "start_date": "2020-06-28", "completion_date": "2022-01-30", "has_results": false, "last_update_posted_date": "2024-09-19", "last_synced_at": "2026-09-04T16:23:59.461Z", "location_count": 1, "location_summary": "Toledo, Ohio", "locations": [ { "city": "Toledo", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT04440475" }, { "nct_id": "NCT05307939", "title": "A Study on Using Cell-Free Tumor DNA (ctDNA) Testing to Decide When to StartRoutine Treatment in People With Human Papilloma Virus (HPV)- Associated Oropharynx Cancer (OPC)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "HPV", "Oropharynx Cancer", "HPV-Related Carcinoma", "HPV-Related Malignancy", "HPV Positive Oropharyngeal Squamous Cell Carcinoma" ], "interventions": [ { "name": "HPV ctDNA Assay", "type": "DIAGNOSTIC_TEST" }, { "name": "MRI Studies", "type": "DIAGNOSTIC_TEST" }, { "name": "EORTC QLQ H&N 35 and C30", "type": "BEHAVIORAL" }, { "name": "MDADI-HN", "type": "BEHAVIORAL" }, { "name": "COST-FACIT", "type": "BEHAVIORAL" }, { "name": "Intensity-Modulated Radiation Therapy (Arm A)", "type": "RADIATION" }, { "name": "Chemoradiation (Arm B)", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "DIAGNOSTIC_TEST", "BEHAVIORAL", "RADIATION", "COMBINATION_PRODUCT" ], "sponsor": "Memorial Sloan Kettering Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 30, "start_date": "2022-03-24", "completion_date": "2027-03-24", "has_results": false, "last_update_posted_date": "2026-04-13", "last_synced_at": "2026-09-04T16:23:59.461Z", "location_count": 8, "location_summary": "Miami, Florida • Basking Ridge, New Jersey • Middletown, New Jersey + 5 more", "locations": [ { "city": "Miami", "state": "Florida" }, { "city": "Basking Ridge", "state": "New Jersey" }, { "city": "Middletown", "state": "New Jersey" }, { "city": "Montvale", "state": "New Jersey" }, { "city": "Commack", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT05307939" }, { "nct_id": "NCT04764851", "title": "Drug-Drug Interaction Study to Evaluate the Effects of Ecopipam on the Pharmacokinetics of Multiple Substrates", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Drug-Interactions" ], "interventions": [ { "name": "ecopipam HCl ~2mg/kg/day", "type": "DRUG" }, { "name": "Cohort 1 Probe Cocktail", "type": "COMBINATION_PRODUCT" }, { "name": "Cohort 2 Probe Cocktail", "type": "COMBINATION_PRODUCT" }, { "name": "Cohort 3 Probe Cocktail", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "DRUG", "COMBINATION_PRODUCT" ], "sponsor": "Emalex Biosciences Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 30, "start_date": "2021-02-18", "completion_date": "2021-05-07", "has_results": false, "last_update_posted_date": "2021-05-24", "last_synced_at": "2026-09-04T16:23:59.461Z", "location_count": 1, "location_summary": "Miami, Florida", "locations": [ { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04764851" }, { "nct_id": "NCT06466655", "title": "Daily Stress and Vascular Function in Midlife as a Risk Factor for Cognitive Decline", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Middle-aged Adults", "Major Depressive Disorder" ], "interventions": [ { "name": "MitoTempol", "type": "DRUG" }, { "name": "Lactated Ringer's (control)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Delaware", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "40 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "40 Years to 55 Years" }, "enrollment_count": 17, "start_date": "2024-05-30", "completion_date": "2025-05-29", "has_results": true, "last_update_posted_date": "2025-10-02", "last_synced_at": "2026-09-04T16:23:59.461Z", "location_count": 1, "location_summary": "Newark, Delaware", "locations": [ { "city": "Newark", "state": "Delaware" } ], "official_url": "https://clinicaltrials.gov/study/NCT06466655" }, { "nct_id": "NCT05334108", "title": "Drug-Drug Interaction Study to Evaluate the Effects of Ecopipam on the Pharmacokinetics of Multiple Substrates for Drug Metabolism and Transport", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Drug Interaction" ], "interventions": [ { "name": "Ecopipam", "type": "DRUG" }, { "name": "Cohort 1 Probe Substrate Cocktail", "type": "COMBINATION_PRODUCT" }, { "name": "Cohort 2 Probe Substrate", "type": "DRUG" }, { "name": "Cohort 3 Probe Substrate Cocktail", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "DRUG", "COMBINATION_PRODUCT" ], "sponsor": "Emalex Biosciences Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 56, "start_date": "2022-04-26", "completion_date": "2022-08-26", "has_results": false, "last_update_posted_date": "2022-12-12", "last_synced_at": "2026-09-04T16:23:59.461Z", "location_count": 1, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05334108" }, { "nct_id": "NCT01017939", "title": "A Drug-Drug Interaction Study of Abiraterone Acetate Plus Prednisone With Dextromethorphan and Theophylline in Patients With Metastatic Castration-Resistant Prostate Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Prostate Neoplasms" ], "interventions": [ { "name": "Abiraterone acetate", "type": "DRUG" }, { "name": "Prednisone", "type": "DRUG" }, { "name": "Dextromethorphan hydrobromide", "type": "DRUG" }, { "name": "Theophylline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 34, "start_date": "2010-01", "completion_date": "2012-04", "has_results": false, "last_update_posted_date": "2013-04-12", "last_synced_at": "2026-09-04T16:23:59.461Z", "location_count": 4, "location_summary": "Beverly Hills, California • San Antonio, Texas", "locations": [ { "city": "Beverly Hills", "state": "California" }, { "city": "Beverly Hills", "state": "California" }, { "city": "San Antonio", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01017939" }, { "nct_id": "NCT04425902", "title": "Evaluation of Pharmacokinetic Interaction Between GSK3640254 and Caffeine, Metoprolol, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin in Healthy Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "HIV Infections" ], "interventions": [ { "name": "GSK3640254 200 mg", "type": "DRUG" }, { "name": "Caffeine 200 mg", "type": "DRUG" }, { "name": "Metoprolol 100 mg", "type": "DRUG" }, { "name": "Montelukast 10 mg", "type": "DRUG" }, { "name": "Flurbiprofen 100 mg", "type": "DRUG" }, { "name": "Omeprazole 40 mg", "type": "DRUG" }, { "name": "Midazolam 5 mg (2.5 mL)", "type": "DRUG" }, { "name": "Digoxin 0.25 mg", "type": "DRUG" }, { "name": "Pravastatin 40 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "ViiV Healthcare", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 20, "start_date": "2020-12-16", "completion_date": "2021-03-10", "has_results": true, "last_update_posted_date": "2024-01-05", "last_synced_at": "2026-09-04T16:23:59.461Z", "location_count": 1, "location_summary": "Las Vegas, Nevada", "locations": [ { "city": "Las Vegas", "state": "Nevada" } ], "official_url": "https://clinicaltrials.gov/study/NCT04425902" }, { "nct_id": "NCT07620548", "title": "Laser Interstitial Thermal Therapy (LiTT) With Cemiplimab or Other Chemotherapy in Recurrent Glioblastomas", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Glioblastoma", "Glioblastoma, IDH-wildtype", "Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype" ], "interventions": [ { "name": "NeuroBlate® Laser Ablation Laser Interstitial Thermal Therapy", "type": "DEVICE" }, { "name": "Cemiplimab", "type": "DRUG" }, { "name": "Chemotherapy", "type": "DRUG" } ], "intervention_types": [ "DEVICE", "DRUG" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 99, "start_date": "2026-08-31", "completion_date": "2032-08-31", "has_results": false, "last_update_posted_date": "2026-06-02", "last_synced_at": "2026-09-04T16:23:59.461Z", "location_count": 2, "location_summary": "Rochester, Minnesota • St Louis, Missouri", "locations": [ { "city": "Rochester", "state": "Minnesota" }, { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT07620548" }, { "nct_id": "NCT02620774", "title": "Tissue Penetration of Ceftolozane/Tazobactam in Diabetic Patients With Lower Limb Infections", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Diabetes", "Wound Infection", "Healthy Volunteers" ], "interventions": [ { "name": "Ceftolozane/tazobactam", "type": "DRUG" }, { "name": "Microdialysis Catheter Insertion", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Hartford Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 16, "start_date": "2016-02-19", "completion_date": "2017-04", "has_results": true, "last_update_posted_date": "2019-01-15", "last_synced_at": "2026-09-04T16:23:59.461Z", "location_count": 1, "location_summary": "Hartford, Connecticut", "locations": [ { "city": "Hartford", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT02620774" } ] }