{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Prolonged+exposure+therapy",
    "query": {
      "intervention": "Prolonged exposure therapy"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 151,
    "total_pages": 16,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Prolonged+exposure+therapy&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T12:53:32.052Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04523922",
      "title": "Oxytocin to Enhance Integrated Treatment for AUD and PTSD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "PTSD",
        "Alcohol Use Disorder"
      ],
      "interventions": [
        {
          "name": "40 IU Intranasal Oxytocin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Concurrent Treatment of PTSD and Substance Use Disorders using Prolonged Exposure",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 175,
      "start_date": "2021-03-29",
      "completion_date": "2026-04-13",
      "has_results": false,
      "last_update_posted_date": "2026-07-27",
      "last_synced_at": "2026-09-03T12:53:32.052Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04523922"
    },
    {
      "nct_id": "NCT01574118",
      "title": "Enhancing Exposure Therapy for Post-traumatic Stress Disorder",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Chronic Posttraumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Revisiting the Trauma memories",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Processing the trauma memories",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Psychoeducation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Trauma Memory Retrieval Trial",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Exposure to video clips related to the patient's trauma",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Breathing retraining",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Exposure Homework",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Compound extinction",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Texas at Austin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 27,
      "start_date": "2012-04",
      "completion_date": "2020-03",
      "has_results": false,
      "last_update_posted_date": "2022-08-29",
      "last_synced_at": "2026-09-03T12:53:32.052Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01574118"
    },
    {
      "nct_id": "NCT03343028",
      "title": "Biomarker Establishment for Superior Treatment of PTSD",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "PTSD"
      ],
      "interventions": [
        {
          "name": "Psychotherapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 292,
      "start_date": "2016-09",
      "completion_date": "2019-09-30",
      "has_results": false,
      "last_update_posted_date": "2020-02-12",
      "last_synced_at": "2026-09-03T12:53:32.052Z",
      "location_count": 2,
      "location_summary": "Palo Alto, California • Albuquerque, New Mexico",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03343028"
    },
    {
      "nct_id": "NCT02586064",
      "title": "Comparative Effectiveness of Two Treatments for Veterans With PTSD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Posttraumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Interpersonal Therapy for PTSD",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Prolonged Exposure",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 115,
      "start_date": "2016-09-01",
      "completion_date": "2020-03-31",
      "has_results": true,
      "last_update_posted_date": "2021-07-07",
      "last_synced_at": "2026-09-03T12:53:32.052Z",
      "location_count": 2,
      "location_summary": "New Orleans, Louisiana • Providence, Rhode Island",
      "locations": [
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02586064"
    },
    {
      "nct_id": "NCT00475241",
      "title": "Exposure Therapy for Chronic PTSD: Efficacy and Mechanisms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Combat Disorders",
        "Posttraumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Prolonged Exposure therapy for PTSD",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Present centered therapy for PTSD",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2008-01",
      "completion_date": "2010-07",
      "has_results": true,
      "last_update_posted_date": "2019-02-15",
      "last_synced_at": "2026-09-03T12:53:32.052Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00475241"
    },
    {
      "nct_id": "NCT02290639",
      "title": "Brief Cognitive Behavioral Treatment of Deployment-Related PTSD Symptoms in Primary Care Settings",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-Traumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Brief Cognitive Behavioral Treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Minimal Contact",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 74,
      "start_date": "2012-12",
      "completion_date": "2015-11",
      "has_results": false,
      "last_update_posted_date": "2016-01-12",
      "last_synced_at": "2026-09-03T12:53:32.052Z",
      "location_count": 2,
      "location_summary": "Lackland Air Force Base, Texas • Randolph Air Force Base, Texas",
      "locations": [
        {
          "city": "Lackland Air Force Base",
          "state": "Texas"
        },
        {
          "city": "Randolph Air Force Base",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02290639"
    },
    {
      "nct_id": "NCT06968832",
      "title": "Project COMET: Massed Prolonged Exposure for PTSD and SUD",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Posttraumatic Stress Disorder (PTSD)",
        "Substance Use Disorders (SUD)",
        "Comorbidity",
        "Trauma and Stressor Related Disorders"
      ],
      "interventions": [
        {
          "name": "Massed Prolonged Exposure Therapy (M-PE)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard outpatient SUD care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 168,
      "start_date": "2025-09-02",
      "completion_date": "2029-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-10-27",
      "last_synced_at": "2026-09-03T12:53:32.052Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06968832"
    },
    {
      "nct_id": "NCT05974631",
      "title": "Evaluating Treatments for Suicidal Veterans With PTSD",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Self-directed Violence",
        "Post-traumatic Stress Disorder (PTSD)"
      ],
      "interventions": [
        {
          "name": "Dialectical Behavior Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Dialectical Behavior Therapy Prolonged Exposure protocol",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Prolonged Exposure therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Suicide risk management",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 125,
      "start_date": "2024-07-08",
      "completion_date": "2028-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-16",
      "last_synced_at": "2026-09-03T12:53:32.052Z",
      "location_count": 4,
      "location_summary": "Minneapolis, Minnesota • Durham, North Carolina • San Antonio, Texas + 1 more",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05974631"
    },
    {
      "nct_id": "NCT00632632",
      "title": "Virtual Reality & D-cycloserine (DCS) for Posttraumatic Stress Disorder (PTSD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Posttraumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "D-Cycloserine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 25,
      "start_date": "2005-01",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2015-08-27",
      "last_synced_at": "2026-09-03T12:53:32.052Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00632632"
    },
    {
      "nct_id": "NCT02522741",
      "title": "Safe Mothers, Safe Children Initiative",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Child Maltreatment"
      ],
      "interventions": [
        {
          "name": "Parenting STAIR",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2010-11",
      "completion_date": "2016-04",
      "has_results": false,
      "last_update_posted_date": "2016-12-22",
      "last_synced_at": "2026-09-03T12:53:32.052Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02522741"
    }
  ]
}