{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Prophylactic+antibiotic&page=2",
    "query": {
      "intervention": "Prophylactic antibiotic",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Prophylactic+antibiotic&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-26T00:13:39.830Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03578965",
      "title": "Does Antibiotic Prophylaxis Reduce Wound Complications After Vulvar Excision of Premalignant Lesions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Premalignant Vulvar Lesion",
        "Benign Vulvar Lesion"
      ],
      "interventions": [
        {
          "name": "Cefazolin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 50,
      "start_date": "2018-07-13",
      "completion_date": "2021-11-23",
      "has_results": true,
      "last_update_posted_date": "2022-11-21",
      "last_synced_at": "2026-09-26T00:13:39.830Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03578965"
    },
    {
      "nct_id": "NCT00016835",
      "title": "Treating Periodontal Infection: Effects on Glycemic",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Periodontal Disease",
        "Diabetes Mellitus, Type 2"
      ],
      "interventions": [
        {
          "name": "Supra-gingival scaling and placebo",
          "type": "PROCEDURE"
        },
        {
          "name": "Subgingival scaling and metronidazole",
          "type": "PROCEDURE"
        },
        {
          "name": "Subgingival scaling and doxycycline",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 46,
      "start_date": "2001-10-17",
      "completion_date": "2004-09-03",
      "has_results": false,
      "last_update_posted_date": "2017-07-19",
      "last_synced_at": "2026-09-26T00:13:39.830Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00016835"
    },
    {
      "nct_id": "NCT03275519",
      "title": "Antibiotic Use in Distal Hypospadias Repair",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypospadias"
      ],
      "interventions": [
        {
          "name": "Randomization to not receive prophylactic antibiotics after surgery.",
          "type": "OTHER"
        },
        {
          "name": "Randomization to receive prophylactic antibiotics after surgery",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Arkansas Children's Hospital Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": "6 Years",
        "sex": "MALE",
        "summary": "3 Months to 6 Years · Male only"
      },
      "enrollment_count": 48,
      "start_date": "2015-01-19",
      "completion_date": "2017-04-19",
      "has_results": false,
      "last_update_posted_date": "2017-09-07",
      "last_synced_at": "2026-09-26T00:13:39.830Z",
      "location_count": 1,
      "location_summary": "Little Rock, Arkansas",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03275519"
    },
    {
      "nct_id": "NCT02511054",
      "title": "Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Trial to Determine Safety and Protective Efficacy of Sanaria PfSPZ Challenge With Concurrent Pyrimethamine Treatment That Inhibits Development of Asexual B...",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Malaria"
      ],
      "interventions": [
        {
          "name": "Chloroquine (CQ)",
          "type": "DRUG"
        },
        {
          "name": "Pyrimethamine (PYR)",
          "type": "DRUG"
        },
        {
          "name": "Sanaria PfSPZ Challenge (NF54)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BIOLOGICAL"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 57,
      "start_date": "2015-07-21",
      "completion_date": "2017-06-01",
      "has_results": false,
      "last_update_posted_date": "2017-07-02",
      "last_synced_at": "2026-09-26T00:13:39.830Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02511054"
    },
    {
      "nct_id": "NCT01608854",
      "title": "Comparison of Antibiotic Protocols in Spine Patients With Postoperative Drains",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Surgical Wound Infection",
        "Spinal Deformity",
        "Spinal Degeneration"
      ],
      "interventions": [
        {
          "name": "Antibiotic Protocol",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 539,
      "start_date": "2008-11",
      "completion_date": "2012-04",
      "has_results": false,
      "last_update_posted_date": "2016-06-10",
      "last_synced_at": "2026-09-26T00:13:39.830Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01608854"
    },
    {
      "nct_id": "NCT03087656",
      "title": "Antibiotics to Decrease Post ERCP Cholangitis",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cholangitis"
      ],
      "interventions": [
        {
          "name": "Ceftriaxone",
          "type": "DRUG"
        },
        {
          "name": "Levofloxacin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 200,
      "start_date": "2017-03-29",
      "completion_date": "2024-02-23",
      "has_results": false,
      "last_update_posted_date": "2023-03-06",
      "last_synced_at": "2026-09-26T00:13:39.830Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03087656"
    },
    {
      "nct_id": "NCT05519579",
      "title": "Intrathecal Chemoprophylaxis to Prevent Neurotoxicity Associated With Blinatumomab Therapy for Acute Lymphoblastic Leukemia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Lymphoblastic Leukemia"
      ],
      "interventions": [
        {
          "name": "Methotrexate",
          "type": "DRUG"
        },
        {
          "name": "Blinatumomab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Northside Hospital, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2023-06-30",
      "completion_date": "2026-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-20",
      "last_synced_at": "2026-09-26T00:13:39.830Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05519579"
    },
    {
      "nct_id": "NCT01296542",
      "title": "A Comparison of Prophylactic Antibacterial Efficacy of Besivance vs. VIGAMOX Prior to Cataract Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cataracts"
      ],
      "interventions": [
        {
          "name": "Moxifloxacin Ophthalmic",
          "type": "DRUG"
        },
        {
          "name": "Besifloxacin Ophthalmic",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bucci Laser Vision Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2011-05",
      "completion_date": "2013-01",
      "has_results": true,
      "last_update_posted_date": "2020-12-08",
      "last_synced_at": "2026-09-26T00:13:39.830Z",
      "location_count": 1,
      "location_summary": "Wilkes-Barre, Pennsylvania",
      "locations": [
        {
          "city": "Wilkes-Barre",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01296542"
    },
    {
      "nct_id": "NCT00634166",
      "title": "Effects of Therapy With Sulfamylon® 5% Topical Solution Compared to a Historical Control Group",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Burns"
      ],
      "interventions": [
        {
          "name": "Sulfamylon® For 5 % Topical Solution",
          "type": "DRUG"
        },
        {
          "name": "Topical Antimicrobial/Antifungal Medications",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mylan Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "3 Months and older"
      },
      "enrollment_count": 220,
      "start_date": "2007-09",
      "completion_date": "2014-04",
      "has_results": true,
      "last_update_posted_date": "2022-09-29",
      "last_synced_at": "2026-09-26T00:13:39.830Z",
      "location_count": 9,
      "location_summary": "Mobile, Alabama • Redlands, California • Gainesville, Florida + 6 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Redlands",
          "state": "California"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Maywood",
          "state": "Illinois"
        },
        {
          "city": "Springfield",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00634166"
    },
    {
      "nct_id": "NCT04754737",
      "title": "Antibiotic Usage Prior to OnabotulinumtoxinA Injection",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Antibiotic Stewardship",
        "Overactive Bladder",
        "Onabotulinumtoxin A",
        "UTI"
      ],
      "interventions": [
        {
          "name": "No antibiotic",
          "type": "OTHER"
        },
        {
          "name": "Prophylactic antibiotic",
          "type": "OTHER"
        },
        {
          "name": "cystoscopic injection of onabotulinumtoxinA",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Benaroya Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2021-03-23",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2024-05-24",
      "last_synced_at": "2026-09-26T00:13:39.830Z",
      "location_count": 1,
      "location_summary": "Stony Brook, New York",
      "locations": [
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04754737"
    }
  ]
}