{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Prophylactic+antibiotics&page=2",
    "query": {
      "intervention": "Prophylactic antibiotics",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 115,
    "total_pages": 12,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Prophylactic+antibiotics&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Prophylactic+antibiotics&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-07T08:11:52.577Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01098448",
      "title": "Control of Periodontal Infections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Periodontitis"
      ],
      "interventions": [
        {
          "name": "scaling and root planing",
          "type": "OTHER"
        },
        {
          "name": "local tetracycline",
          "type": "DRUG"
        },
        {
          "name": "systemic metronidazole and amoxicillin",
          "type": "DRUG"
        },
        {
          "name": "surgery",
          "type": "OTHER"
        },
        {
          "name": "local antibiotics and systemic metronidazole and amoxicillin",
          "type": "DRUG"
        },
        {
          "name": "local tetracycline and periodontal surgery",
          "type": "OTHER"
        },
        {
          "name": "periodontal surgery and systemic metronidazole and amoxicillin",
          "type": "OTHER"
        },
        {
          "name": "surgery, local tetracycline, systemic metronidazole and amoxicillin",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "The Forsyth Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "20 Years and older"
      },
      "enrollment_count": 187,
      "start_date": "1999-09",
      "completion_date": "2004-12",
      "has_results": false,
      "last_update_posted_date": "2010-04-02",
      "last_synced_at": "2026-10-07T08:11:52.577Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01098448"
    },
    {
      "nct_id": "NCT06396078",
      "title": "Improvement of PPROM Management With Prophylactic Antimicrobial Therapy (iPROMPT)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Preterm Premature Rupture of Membrane",
        "Pregnancy, High Risk",
        "Preterm Birth"
      ],
      "interventions": [
        {
          "name": "Ceftriaxone 1000 MG",
          "type": "DRUG"
        },
        {
          "name": "Clarithromycin 500mg",
          "type": "DRUG"
        },
        {
          "name": "Metronidazole 500 mg",
          "type": "DRUG"
        },
        {
          "name": "Ampicillin 2 GM Injection",
          "type": "DRUG"
        },
        {
          "name": "Amoxicillin 250 MG",
          "type": "DRUG"
        },
        {
          "name": "Azithromycin",
          "type": "DRUG"
        },
        {
          "name": "Erythromycin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 56,
      "start_date": "2024-07-18",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-01-27",
      "last_synced_at": "2026-10-07T08:11:52.577Z",
      "location_count": 2,
      "location_summary": "Columbus, Ohio • Galveston, Texas",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Galveston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06396078"
    },
    {
      "nct_id": "NCT00000933",
      "title": "Effects of MAC Preventive Therapy on Disease-Causing Bacteria in HIV-Infected Patients: A Substudy of CPCRA 048",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mycobacterium Avium-intracellulare Infection",
        "HIV Infections",
        "Pneumococcal Infections"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 326,
      "start_date": null,
      "completion_date": "2000-07",
      "has_results": false,
      "last_update_posted_date": "2021-10-29",
      "last_synced_at": "2026-10-07T08:11:52.577Z",
      "location_count": 15,
      "location_summary": "San Francisco, California • Denver, Colorado • Washington D.C., District of Columbia + 11 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00000933"
    },
    {
      "nct_id": "NCT00016835",
      "title": "Treating Periodontal Infection: Effects on Glycemic",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Periodontal Disease",
        "Diabetes Mellitus, Type 2"
      ],
      "interventions": [
        {
          "name": "Supra-gingival scaling and placebo",
          "type": "PROCEDURE"
        },
        {
          "name": "Subgingival scaling and metronidazole",
          "type": "PROCEDURE"
        },
        {
          "name": "Subgingival scaling and doxycycline",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 46,
      "start_date": "2001-10-17",
      "completion_date": "2004-09-03",
      "has_results": false,
      "last_update_posted_date": "2017-07-19",
      "last_synced_at": "2026-10-07T08:11:52.577Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00016835"
    },
    {
      "nct_id": "NCT03380273",
      "title": "AO Multicenter Intervention Trial for Prevention of Surgical Site Infection",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Surgical Site Infection"
      ],
      "interventions": [
        {
          "name": "Implementation of the AO Trauma SSI Prevention Bundle",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "AO Clinical Investigation and Publishing Documentation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 222,
      "start_date": "2019-12-06",
      "completion_date": "2021-12-31",
      "has_results": false,
      "last_update_posted_date": "2022-01-18",
      "last_synced_at": "2026-10-07T08:11:52.577Z",
      "location_count": 8,
      "location_summary": "Los Angeles, California • Lexington, Kentucky • Worcester, Massachusetts + 5 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Worcester",
          "state": "Massachusetts"
        },
        {
          "city": "Columbia",
          "state": "Missouri"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03380273"
    },
    {
      "nct_id": "NCT04411199",
      "title": "D-PLEX 312 - Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection (SHIELD II)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Surgical Site Infection",
        "Colon Surgery",
        "Abdominal Surgery",
        "Post-Op Infection"
      ],
      "interventions": [
        {
          "name": "D-PLEX",
          "type": "DRUG"
        },
        {
          "name": "Standard of Care (SoC)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "PolyPid Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 975,
      "start_date": "2020-12-15",
      "completion_date": "2025-05-10",
      "has_results": true,
      "last_update_posted_date": "2026-07-13",
      "last_synced_at": "2026-10-07T08:11:52.577Z",
      "location_count": 5,
      "location_summary": "Augusta, Georgia • New Orleans, Louisiana • St Louis, Missouri + 2 more",
      "locations": [
        {
          "city": "Augusta",
          "state": "Georgia"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04411199"
    },
    {
      "nct_id": "NCT01105767",
      "title": "Methicillin-resistant Staphylococcus Aureus (MRSA) Skin and Soft Tissue Infection (SSTI) Prevention in Military Trainees",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Staphylococcus Aureus",
        "MRSA Skin Infections",
        "Staphylococcal Skin Infections"
      ],
      "interventions": [
        {
          "name": "Chlorhexidine gluconate",
          "type": "DRUG"
        },
        {
          "name": "Supplemental training, education and hygiene",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Henry M. Jackson Foundation for the Advancement of Military Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "42 Years",
        "sex": "MALE",
        "summary": "18 Years to 42 Years · Male only"
      },
      "enrollment_count": 30209,
      "start_date": "2010-05",
      "completion_date": "2012-01",
      "has_results": true,
      "last_update_posted_date": "2023-02-03",
      "last_synced_at": "2026-10-07T08:11:52.577Z",
      "location_count": 1,
      "location_summary": "Columbus, Georgia",
      "locations": [
        {
          "city": "Columbus",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01105767"
    },
    {
      "nct_id": "NCT03050515",
      "title": "Fecal Microbiota Transplantation for the Treatment of Recurrent Urinary Tract Infections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Recurrent Urinary Tract Infection"
      ],
      "interventions": [
        {
          "name": "Fecal Microbiota Transplantation",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 100 Years · Female only"
      },
      "enrollment_count": 12,
      "start_date": "2018-02-05",
      "completion_date": "2020-02-23",
      "has_results": false,
      "last_update_posted_date": "2020-06-18",
      "last_synced_at": "2026-10-07T08:11:52.577Z",
      "location_count": 1,
      "location_summary": "Orange, California",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03050515"
    },
    {
      "nct_id": "NCT00185939",
      "title": "The Use of Prophylactic Antibiotics In the Management of Dog Bites",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Bite",
        "Wound",
        "Infection"
      ],
      "interventions": [
        {
          "name": "Augmentin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 125,
      "start_date": "2003-08",
      "completion_date": "2005-11",
      "has_results": false,
      "last_update_posted_date": "2006-12-05",
      "last_synced_at": "2026-10-07T08:11:52.577Z",
      "location_count": 3,
      "location_summary": "Burlingame, California • San Francisco, California • Stanford, California",
      "locations": [
        {
          "city": "Burlingame",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00185939"
    },
    {
      "nct_id": "NCT06190197",
      "title": "Prophylactic Antibiotics in Cystectomy With Diversion",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Muscle-Invasive Bladder Carcinoma",
        "Radical Cystectomy",
        "Ileal Conduit",
        "Neobladder Diversion"
      ],
      "interventions": [
        {
          "name": "Prophylactic antibiotics postoperatively.",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2024-05-13",
      "completion_date": "2027-10-15",
      "has_results": false,
      "last_update_posted_date": "2025-11-17",
      "last_synced_at": "2026-10-07T08:11:52.577Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06190197"
    }
  ]
}