{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Propofol+1+mg%2Fkg", "query": { "intervention": "Propofol 1 mg/kg" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 68, "total_pages": 7, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Propofol+1+mg%2Fkg&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-24T07:05:58.473Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02410707", "title": "Adjunctive Nitrous Oxide During Emergency Department Propofol Sedation in Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Joint Dislocation", "Perianal Abscess", "Abscess" ], "interventions": [ { "name": "Nitrous Oxide arm", "type": "DRUG" }, { "name": "Propofol", "type": "DRUG" }, { "name": "Oxygen", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Albert Einstein Healthcare Network", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 43, "start_date": "2015-02", "completion_date": "2018-02", "has_results": true, "last_update_posted_date": "2020-04-08", "last_synced_at": "2026-09-24T07:05:58.473Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02410707" }, { "nct_id": "NCT07369128", "title": "Propofol-Only Versus Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance Imaging", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "MRI Sedation", "Pediatric Sedation", "Propofol Dosage", "Emergence Delirium, Anesthesia", "Recovery Time", "Dexmedetomidine" ], "interventions": [ { "name": "Dexmedetomidine (IV) 0.5 mcg/kg", "type": "DRUG" }, { "name": "Propofol (IV) 2-4 mg/kg", "type": "DRUG" }, { "name": "Dexmedetomidine (IV) 1 mcg/kg", "type": "DRUG" }, { "name": "Propofol (IV) 1-2 mg/kg", "type": "DRUG" }, { "name": "Propofol (IV) Infusion 250 mcg/kg/min", "type": "DRUG" }, { "name": "Propofol (IV) Infusion 150 mcg/kg/min", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boston Children's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "12 Years", "sex": "ALL", "summary": "1 Year to 12 Years" }, "enrollment_count": 105, "start_date": "2026-06-30", "completion_date": "2028-03", "has_results": false, "last_update_posted_date": "2026-09-21", "last_synced_at": "2026-09-24T07:05:58.473Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT07369128" }, { "nct_id": "NCT03513757", "title": "Dexmedetomidine and Propofol for Pediatric MRI Sedation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Headache", "Tumor", "Seizure Disorder", "Neurofibromatoses", "Hydrocephalus", "Abdominal Neoplasm", "Spine Deformity" ], "interventions": [ { "name": "propofol", "type": "DRUG" }, { "name": "Dexmedetomidine", "type": "DRUG" }, { "name": "Glycopyrrolate", "type": "DRUG" }, { "name": "Lidocaine 1% Injectable Solution", "type": "DRUG" }, { "name": "Nitrous Oxide", "type": "DRUG" }, { "name": "Sevoflurane", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Medical College of Wisconsin", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Months", "maximum_age": "60 Months", "sex": "ALL", "summary": "12 Months to 60 Months" }, "enrollment_count": 40, "start_date": "2018-03-04", "completion_date": "2018-10-21", "has_results": true, "last_update_posted_date": "2020-02-21", "last_synced_at": "2026-09-24T07:05:58.473Z", "location_count": 1, "location_summary": "Milwaukee, Wisconsin", "locations": [ { "city": "Milwaukee", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT03513757" }, { "nct_id": "NCT02430389", "title": "Effect of Remifentanil on Hemodynamic Stability During Placement of a Mayfield Head Fixation Device for Craniotomy", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Surgery" ], "interventions": [ { "name": "Remifentanil", "type": "DRUG" }, { "name": "Normal Saline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Northwestern University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2012-07", "completion_date": "2014-12", "has_results": true, "last_update_posted_date": "2015-06-30", "last_synced_at": "2026-09-24T07:05:58.473Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT02430389" }, { "nct_id": "NCT01739933", "title": "The MENDS2 Study, Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients With Acute Respiratory Failure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Sepsis", "Delirium", "Impaired Cognition" ], "interventions": [ { "name": "Dexmedetomidine", "type": "DRUG" }, { "name": "Propofol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 438, "start_date": "2013-05-15", "completion_date": "2019-07", "has_results": true, "last_update_posted_date": "2021-06-07", "last_synced_at": "2026-09-24T07:05:58.473Z", "location_count": 11, "location_summary": "San Francisco, California • Baton Rouge, Louisiana • Boston, Massachusetts + 7 more", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Baton Rouge", "state": "Louisiana" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Springfield", "state": "Massachusetts" }, { "city": "Asheville", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT01739933" }, { "nct_id": "NCT00997321", "title": "Propofol Versus Ketamine for Moderate Procedural Sedation in the Emergency Department (ED)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Sedation" ], "interventions": [ { "name": "propofol", "type": "DRUG" }, { "name": "Ketamine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Hennepin Healthcare Research Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 100, "start_date": "2007-07", "completion_date": "2009-10", "has_results": true, "last_update_posted_date": "2012-04-02", "last_synced_at": "2026-09-24T07:05:58.473Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00997321" }, { "nct_id": "NCT01214057", "title": "Total Intravenous Anesthesia (TIVA) vs. Inhaled Anesthesia for Endoscopic Sinus Surgery.", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Chronic Rhinosinusitis" ], "interventions": [ { "name": "Propofol and Remifentanyl", "type": "DRUG" }, { "name": "Sevoflurane and Remifentanyl", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The University of Texas Health Science Center, Houston", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 23, "start_date": "2010-05", "completion_date": "2012-10", "has_results": true, "last_update_posted_date": "2021-11-01", "last_synced_at": "2026-09-24T07:05:58.473Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01214057" }, { "nct_id": "NCT07835295", "title": "REMIfentanil (2 vs. 4 mcg/kg) Facilitated Intubation Without Neuromuscular Blockade Versus Succinylcholine and Rocuronium With Sugammadex for Endotracheal Intubation in Spine Surgery Requiring Motor Evoked Potential Monitoring", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Airway Management", "Endotracheal Intubation" ], "interventions": [ { "name": "Low-Dose Remifentanil", "type": "DRUG" }, { "name": "High-Dose Remifentanil", "type": "DRUG" }, { "name": "Succinylcholine", "type": "DRUG" }, { "name": "Rocuronium", "type": "DRUG" }, { "name": "Sugammadex", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 316, "start_date": "2026-09", "completion_date": "2029-01", "has_results": false, "last_update_posted_date": "2026-09-22", "last_synced_at": "2026-09-24T07:05:58.473Z", "location_count": 1, "location_summary": "Jacksonville, Florida", "locations": [ { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07835295" }, { "nct_id": "NCT06029049", "title": "Comparison of Intubation Conditions During Rapid Sequence Induction Obtained With Modified Time Principal Induction With a Standard Intubation Dose of Rocuronium Versus Succinylcholine", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Anesthesia" ], "interventions": [ { "name": "Modified Time Principle Induction (MTPI) with rocuronium", "type": "DRUG" }, { "name": "RSI succinylcholine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The University of Texas Health Science Center, Houston", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 152, "start_date": "2023-09-13", "completion_date": "2025-07-01", "has_results": false, "last_update_posted_date": "2024-12-10", "last_synced_at": "2026-09-24T07:05:58.473Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06029049" }, { "nct_id": "NCT04197570", "title": "Opioid-free Anesthesia for Open Cardiac Surgery: A Prospective Randomized Controlled Trial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Opioid Use", "Heart; Surgery, Heart, Functional Disturbance as Result", "Anesthesia" ], "interventions": [ { "name": "Opioid Anesthetics", "type": "DRUG" }, { "name": "Non Opioid Analgesics", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Benaroya Research Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 9, "start_date": "2020-02-04", "completion_date": "2020-03-14", "has_results": false, "last_update_posted_date": "2020-07-28", "last_synced_at": "2026-09-24T07:05:58.473Z", "location_count": 1, "location_summary": "Seattle, Washington", "locations": [ { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT04197570" } ] }