{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Propofol+or+Sevoflurane", "query": { "intervention": "Propofol or Sevoflurane" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 37, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Propofol+or+Sevoflurane&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-26T19:26:08.013Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02726620", "title": "Decision Support for Intraoperative Low Blood Pressure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hypotension" ], "interventions": [ { "name": "Attending real-time decision support", "type": "PROCEDURE" }, { "name": "In-room real-time decision support", "type": "PROCEDURE" }, { "name": "Attending feedback emails", "type": "PROCEDURE" }, { "name": "In-room provider feedback emails", "type": "PROCEDURE" }, { "name": "Anesthesia Information Management System (AIMS)", "type": "DEVICE" }, { "name": "Perioperative Data Warehouse (PDW)", "type": "DEVICE" }, { "name": "General anesthesia", "type": "PROCEDURE" }, { "name": "Pager system", "type": "DEVICE" }, { "name": "Central neuraxial anesthesia", "type": "PROCEDURE" }, { "name": "Non-cardiac surgery", "type": "PROCEDURE" }, { "name": "Propofol", "type": "DRUG" }, { "name": "Sevoflurane", "type": "DRUG" }, { "name": "Desflurane", "type": "DRUG" }, { "name": "Isoflurane", "type": "DRUG" }, { "name": "Ephedrine", "type": "DRUG" }, { "name": "Phenylephrine", "type": "DRUG" }, { "name": "Norepinephrine", "type": "DRUG" }, { "name": "Epinephrine", "type": "DRUG" }, { "name": "Dobutamine", "type": "DRUG" }, { "name": "Dopamine", "type": "DRUG" }, { "name": "Isoproterenol", "type": "DRUG" }, { "name": "Milrinone", "type": "DRUG" }, { "name": "Atropine", "type": "DRUG" }, { "name": "Glycopyrrolate", "type": "DRUG" }, { "name": "Vasopressin", "type": "DRUG" }, { "name": "Terlipressin", "type": "DRUG" }, { "name": "Sodium Chloride 0.9%", "type": "DRUG" }, { "name": "Ringer's lactate", "type": "DRUG" }, { "name": "Hydroxyethyl starch solutions", "type": "DRUG" }, { "name": "Fresh Frozen Plasma", "type": "DRUG" }, { "name": "Packed Red Blood Cells", "type": "DRUG" }, { "name": "Albumin solutions", "type": "DRUG" }, { "name": "Plasma-Lyte", "type": "DRUG" }, { "name": "Lidocaine", "type": "DRUG" }, { "name": "Bupivacaine", "type": "DRUG" }, { "name": "Levobupivacaine", "type": "DRUG" }, { "name": "Ropivacaine", "type": "DRUG" }, { "name": "Mepivacaine", "type": "DRUG" }, { "name": "Tetracaine", "type": "DRUG" }, { "name": "Prilocaine", "type": "DRUG" }, { "name": "Procaine", "type": "DRUG" }, { "name": "Chloroprocaine", "type": "DRUG" }, { "name": "Benzocaine", "type": "DRUG" }, { "name": "Articaine", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "DEVICE", "DRUG" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "60 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "60 Years to 100 Years" }, "enrollment_count": 22435, "start_date": "2017-01-05", "completion_date": "2018-12-29", "has_results": true, "last_update_posted_date": "2019-05-16", "last_synced_at": "2026-09-26T19:26:08.013Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT02726620" }, { "nct_id": "NCT05279898", "title": "Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERies", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Postoperative Delirium", "Hemodynamic Instability", "Pain", "Neurocognitive Dysfunction" ], "interventions": [ { "name": "EEG Monitoring", "type": "DEVICE" }, { "name": "Ropivacaine", "type": "DRUG" }, { "name": "Ketamine", "type": "DRUG" }, { "name": "Remifentanil", "type": "DRUG" }, { "name": "Dexmedetomidine", "type": "DRUG" }, { "name": "Rocuronium", "type": "DRUG" }, { "name": "Propofol", "type": "DRUG" } ], "intervention_types": [ "DEVICE", "DRUG" ], "sponsor": "Beth Israel Deaconess Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "60 Years", "maximum_age": null, "sex": "ALL", "summary": "60 Years and older" }, "enrollment_count": 70, "start_date": "2023-02-28", "completion_date": "2024-12-31", "has_results": true, "last_update_posted_date": "2025-11-26", "last_synced_at": "2026-09-26T19:26:08.013Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT05279898" }, { "nct_id": "NCT05025397", "title": "A Study of Danavorexton in Anesthetized Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy Volunteers" ], "interventions": [ { "name": "Danavorexton", "type": "DRUG" }, { "name": "Danavorexton Placebo", "type": "DRUG" }, { "name": "Propofol", "type": "DRUG" }, { "name": "Sevoflurane", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 28, "start_date": "2021-09-28", "completion_date": "2022-03-08", "has_results": false, "last_update_posted_date": "2022-05-10", "last_synced_at": "2026-09-26T19:26:08.013Z", "location_count": 1, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05025397" }, { "nct_id": "NCT00418457", "title": "Regional Anesthesia and Breast Cancer Recurrence", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Breast Neoplasms" ], "interventions": [ { "name": "General anesthesia and opioids", "type": "DRUG" }, { "name": "Regional analgesia and propofol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The Cleveland Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "FEMALE", "summary": "18 Years to 85 Years · Female only" }, "enrollment_count": 2108, "start_date": "2007-01", "completion_date": "2019-12", "has_results": true, "last_update_posted_date": "2020-06-16", "last_synced_at": "2026-09-26T19:26:08.013Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00418457" }, { "nct_id": "NCT03034096", "title": "General Anesthetics in CAncer REsection Surgery (GA-CARES) Trial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Anesthesia, General", "Surgical Oncology" ], "interventions": [ { "name": "Propofol", "type": "DRUG" }, { "name": "Volatile Agent", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Stony Brook University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1826, "start_date": "2017-01-31", "completion_date": "2024-09-30", "has_results": false, "last_update_posted_date": "2025-05-04", "last_synced_at": "2026-09-26T19:26:08.013Z", "location_count": 5, "location_summary": "Buffalo, New York • New Hyde Park, New York • New York, New York + 2 more", "locations": [ { "city": "Buffalo", "state": "New York" }, { "city": "New Hyde Park", "state": "New York" }, { "city": "New York", "state": "New York" }, { "city": "Rochester", "state": "New York" }, { "city": "Stony Brook", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT03034096" }, { "nct_id": "NCT01566838", "title": "Continuous Subpleural Infusion of Bupivacaine", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Postoperative Pain" ], "interventions": [ { "name": "Subpleural pain catheter with infusion of 0.125% bupivacaine", "type": "DRUG" }, { "name": "Standard acute pain management", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Inova Health Care Services", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 83, "start_date": "2012-10", "completion_date": "2015-12", "has_results": true, "last_update_posted_date": "2017-12-20", "last_synced_at": "2026-09-26T19:26:08.013Z", "location_count": 1, "location_summary": "Falls Church, Virginia", "locations": [ { "city": "Falls Church", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT01566838" }, { "nct_id": "NCT04602546", "title": "Evaluation of Bispectral Index (BIS™) and Levels of Sedation With Common Inhalational Anesthetics in Healthy Volunteers (OLIVER)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Anesthesia" ], "interventions": [ { "name": "BIS Complete Monitoring System", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Medtronic - MITG", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 211, "start_date": "2021-02-09", "completion_date": "2022-08-26", "has_results": true, "last_update_posted_date": "2023-04-18", "last_synced_at": "2026-09-26T19:26:08.013Z", "location_count": 3, "location_summary": "San Francisco, California • Durham, North Carolina • Salt Lake City, Utah", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Durham", "state": "North Carolina" }, { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT04602546" }, { "nct_id": "NCT05639686", "title": "TIVA vs TXA in Sinus Surgery to Evaluate Operative Blood Loss and Surgical Field Quality", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Rhinosinusitis Chronic", "Sinus Cancer", "Sinus Polyp", "Encephalocele" ], "interventions": [ { "name": "Tranexamic acid injection", "type": "DRUG" }, { "name": "Total Intravenous Anesthesia", "type": "DRUG" }, { "name": "Inhalational isoflurane", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Our Lady of the Lake Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 100, "start_date": "2023-01-01", "completion_date": "2025-07-01", "has_results": false, "last_update_posted_date": "2023-03-23", "last_synced_at": "2026-09-26T19:26:08.013Z", "location_count": 1, "location_summary": "Baton Rouge, Louisiana", "locations": [ { "city": "Baton Rouge", "state": "Louisiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT05639686" }, { "nct_id": "NCT03435003", "title": "Designing Optimal Prevention and Management of Postoperative Nausea and Emesis for Patients Undergoing Laparoscopic Sleeve Gastrectomy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Post-operative Nausea and Vomiting", "Laparoscopic Sleeve Gastrectomy" ], "interventions": [ { "name": "Aprepitant 80 mg Oral Capsule", "type": "DRUG" }, { "name": "scopolamine transdermal", "type": "DRUG" }, { "name": "Total intravenous anesthesia", "type": "PROCEDURE" }, { "name": "Dexamethasone", "type": "DRUG" }, { "name": "Ondansetron", "type": "DRUG" }, { "name": "Reglan", "type": "DRUG" }, { "name": "Compazine", "type": "DRUG" }, { "name": "Sugammadex", "type": "DRUG" }, { "name": "Propofol", "type": "DRUG" }, { "name": "dexmedetomidine", "type": "DRUG" }, { "name": "Fentanyl", "type": "DRUG" }, { "name": "Sevoflurane", "type": "DRUG" }, { "name": "Desflurane", "type": "DRUG" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Stony Brook University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 83, "start_date": "2017-08-28", "completion_date": "2019-04-01", "has_results": true, "last_update_posted_date": "2024-02-14", "last_synced_at": "2026-09-26T19:26:08.013Z", "location_count": 1, "location_summary": "Stony Brook, New York", "locations": [ { "city": "Stony Brook", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT03435003" }, { "nct_id": "NCT01755234", "title": "Propofol Versus Sevoflurane Recovery After Gynecological Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Surgery", "Anesthesia" ], "interventions": [ { "name": "Sevoflurane", "type": "DRUG" }, { "name": "Propofol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Northwestern University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "64 Years", "sex": "FEMALE", "summary": "18 Years to 64 Years · Female only" }, "enrollment_count": 90, "start_date": "2012-11", "completion_date": "2014-04", "has_results": true, "last_update_posted_date": "2016-03-14", "last_synced_at": "2026-09-26T19:26:08.013Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT01755234" } ] }