{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Prospective+%2F+Subjects+Knee+Arthroplasty",
    "query": {
      "intervention": "Prospective / Subjects Knee Arthroplasty"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 44,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Prospective+%2F+Subjects+Knee+Arthroplasty&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-06T17:10:55.139Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00808613",
      "title": "Optetrak Posterior Stabilized Versus Optetrak Hi-Flex",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthropathy of Knee",
        "Arthritis and/or Post-traumatic Degenerative Problems"
      ],
      "interventions": [
        {
          "name": "Optetrak PS",
          "type": "DEVICE"
        },
        {
          "name": "Optetrak Hi-Flex",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Exactech",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "50 Years to 80 Years"
      },
      "enrollment_count": 0,
      "start_date": "2008-12",
      "completion_date": "2012-01",
      "has_results": false,
      "last_update_posted_date": "2022-09-01",
      "last_synced_at": "2026-10-06T17:10:55.139Z",
      "location_count": 1,
      "location_summary": "Newport News, Virginia",
      "locations": [
        {
          "city": "Newport News",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00808613"
    },
    {
      "nct_id": "NCT01551472",
      "title": "Post Market Study of the 3DKnee™ With E-plus Insert",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Degenerative Joint Disease",
        "Osteoarthritis",
        "Traumatic Arthritis"
      ],
      "interventions": [
        {
          "name": "3DKnee™ System with Vitamin E UHMWPE Tibial Inserts",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Encore Medical, L.P.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "40 Years to 75 Years"
      },
      "enrollment_count": 175,
      "start_date": "2012-04",
      "completion_date": "2022-01",
      "has_results": false,
      "last_update_posted_date": "2022-03-31",
      "last_synced_at": "2026-10-06T17:10:55.139Z",
      "location_count": 6,
      "location_summary": "Burbank, California • Oceanside, California • Fort Myers, Florida + 3 more",
      "locations": [
        {
          "city": "Burbank",
          "state": "California"
        },
        {
          "city": "Oceanside",
          "state": "California"
        },
        {
          "city": "Fort Myers",
          "state": "Florida"
        },
        {
          "city": "City of Saint Peters",
          "state": "Missouri"
        },
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01551472"
    },
    {
      "nct_id": "NCT07286513",
      "title": "Persona SoluTion PPS Femur PMCF",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Rhematoid Arthritis",
        "Osteo Arthritis of the Knee",
        "Traumatic Arthritis of Knee (Diagnosis)",
        "Polyarthritis",
        "Collagen Disorders",
        "Avascular Necrosis of Femoral Condyle",
        "Valgus Deformity",
        "Varus Deformity",
        "Flexion Deformity of Knee"
      ],
      "interventions": [
        {
          "name": "Total knee arthroplasty",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2026-02-26",
      "completion_date": "2037-12",
      "has_results": false,
      "last_update_posted_date": "2026-10-06",
      "last_synced_at": "2026-10-06T17:10:55.139Z",
      "location_count": 4,
      "location_summary": "Denver, Colorado • Louisville, Kentucky • Baltimore, Maryland",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07286513"
    },
    {
      "nct_id": "NCT02501733",
      "title": "Medacta GMK Sphere® Multicenter Post-Market Outcomes Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Medacta GMK Sphere® Medial Knee Prosthesis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medacta USA",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 260,
      "start_date": "2015-06",
      "completion_date": "2024-12-05",
      "has_results": false,
      "last_update_posted_date": "2025-09-25",
      "last_synced_at": "2026-10-06T17:10:55.139Z",
      "location_count": 5,
      "location_summary": "Chicago, Illinois • New Orleans, Louisiana • Oklahoma City, Oklahoma + 2 more",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        },
        {
          "city": "Austin",
          "state": "Texas"
        },
        {
          "city": "Spokane",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02501733"
    },
    {
      "nct_id": "NCT02638480",
      "title": "Effectiveness of KneeMD on Flexion Contracture in Total Knee Arthroplasty Patients",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Flexion Contracture"
      ],
      "interventions": [
        {
          "name": "KneeMD",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Anne Arundel Health System Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2015-11",
      "completion_date": "2019-04",
      "has_results": false,
      "last_update_posted_date": "2019-02-08",
      "last_synced_at": "2026-10-06T17:10:55.139Z",
      "location_count": 1,
      "location_summary": "Annapolis, Maryland",
      "locations": [
        {
          "city": "Annapolis",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02638480"
    },
    {
      "nct_id": "NCT00966979",
      "title": "Triathlon® Partial Knee Replacement (PKR) Outcomes Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthroplasty, Replacement, Knee"
      ],
      "interventions": [
        {
          "name": "Triathlon PKR",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stryker Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 111,
      "start_date": "2010-01",
      "completion_date": "2023-05",
      "has_results": true,
      "last_update_posted_date": "2023-09-13",
      "last_synced_at": "2026-10-06T17:10:55.139Z",
      "location_count": 6,
      "location_summary": "Jacksonville, Florida • Egg Harbor, New Jersey • Buffalo, New York + 3 more",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Egg Harbor",
          "state": "New Jersey"
        },
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "Syracuse",
          "state": "New York"
        },
        {
          "city": "Media",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00966979"
    },
    {
      "nct_id": "NCT04730271",
      "title": "Comparison of Alignment Achieved Using the VELYS Robotic-Assisted Solution Versus Manual Instrumentation in Total Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteo Arthritis Knee",
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Total Knee Replacement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DePuy Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "22 Years to 85 Years"
      },
      "enrollment_count": 200,
      "start_date": "2021-02-23",
      "completion_date": "2023-09-06",
      "has_results": true,
      "last_update_posted_date": "2025-04-27",
      "last_synced_at": "2026-10-06T17:10:55.139Z",
      "location_count": 5,
      "location_summary": "Baltimore, Maryland • Crosby, Minnesota • Charlotte, North Carolina + 2 more",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Crosby",
          "state": "Minnesota"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Germantown",
          "state": "Tennessee"
        },
        {
          "city": "Renton",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04730271"
    },
    {
      "nct_id": "NCT05653102",
      "title": "A Post-Market Domestic (US) and International Data Collection to Assess the Truliant Knee System",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Knee Arthroplasty, Total"
      ],
      "interventions": [
        {
          "name": "Truliant Total Knee System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Exactech",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2019-01-23",
      "completion_date": "2035-07-31",
      "has_results": false,
      "last_update_posted_date": "2024-06-18",
      "last_synced_at": "2026-10-06T17:10:55.139Z",
      "location_count": 5,
      "location_summary": "Aurora, Colorado • DeLand, Florida • Las Vegas, Nevada + 2 more",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "DeLand",
          "state": "Florida"
        },
        {
          "city": "Las Vegas",
          "state": "Nevada"
        },
        {
          "city": "Akron",
          "state": "Ohio"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05653102"
    },
    {
      "nct_id": "NCT00616850",
      "title": "Treatment of Postoperative Pain After Total Knee Arthroplasy Using Intravenous Lidocaine Infusion",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Total Knee Arthroplasty"
      ],
      "interventions": [
        {
          "name": "Continuous femoral catheter block",
          "type": "PROCEDURE"
        },
        {
          "name": "Lidocaine",
          "type": "DRUG"
        },
        {
          "name": "Preservative free normal saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 0,
      "start_date": "2007-10",
      "completion_date": "2009-07",
      "has_results": false,
      "last_update_posted_date": "2014-05-22",
      "last_synced_at": "2026-10-06T17:10:55.139Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00616850"
    },
    {
      "nct_id": "NCT01746524",
      "title": "Prospective, Multiconfiguration Study to Assess Functional Performance of Primary Total Knee Arthroplasty System",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "ATTUNE Primary Total Knee Arthroplasty",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DePuy Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "22 Years to 80 Years"
      },
      "enrollment_count": 1138,
      "start_date": "2012-11-01",
      "completion_date": "2018-03-05",
      "has_results": false,
      "last_update_posted_date": "2019-04-11",
      "last_synced_at": "2026-10-06T17:10:55.139Z",
      "location_count": 9,
      "location_summary": "Orange, California • San Diego, California • Fort Collins, Colorado + 6 more",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Fort Collins",
          "state": "Colorado"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01746524"
    }
  ]
}