{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Prospective+Midazolam",
    "query": {
      "intervention": "Prospective Midazolam"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 33,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Prospective+Midazolam&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-14T20:28:30.592Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01195103",
      "title": "Lusedra (Fospropofol Disodium) for Minimal to Moderate Sedation for Regional Anesthesia Block Prior to Orthopedic Surgery",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Procedural Sedation",
        "Regional Anesthesia Block",
        "Orthopedic Surgery"
      ],
      "interventions": [
        {
          "name": "Fospropofol disodium",
          "type": "DRUG"
        },
        {
          "name": "Placebo + Midazolam",
          "type": "DRUG"
        },
        {
          "name": "Fentanyl",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 13,
      "start_date": "2011-02",
      "completion_date": "2011-03",
      "has_results": true,
      "last_update_posted_date": "2012-06-29",
      "last_synced_at": "2026-09-14T20:28:30.592Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01195103"
    },
    {
      "nct_id": "NCT00248729",
      "title": "Effectiveness and Safety Study of Etomidate Versus Midazolam to Help Place a Breathing Tube Outside of the Hospital.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "Etomidate (20mg) or Midazolam (7mg)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "St. Luke's Hospital, Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": null,
      "start_date": "2002-10",
      "completion_date": "2005-11",
      "has_results": false,
      "last_update_posted_date": "2025-05-14",
      "last_synced_at": "2026-09-14T20:28:30.592Z",
      "location_count": 1,
      "location_summary": "Bethlehem, Pennsylvania",
      "locations": [
        {
          "city": "Bethlehem",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00248729"
    },
    {
      "nct_id": "NCT04663269",
      "title": "Regional Erector Spinae Analgesic Block vs Standard of Care Undergoing Percutaneous Nephrolithotomy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Kidney Stone",
        "Surgery"
      ],
      "interventions": [
        {
          "name": "4mg PF Dexamethasone",
          "type": "DRUG"
        },
        {
          "name": "Control Test",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2020-02-24",
      "completion_date": "2020-09-24",
      "has_results": false,
      "last_update_posted_date": "2021-04-23",
      "last_synced_at": "2026-09-14T20:28:30.592Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04663269"
    },
    {
      "nct_id": "NCT02290873",
      "title": "A Phase III Study of the Efficacy and Safety of Remimazolam Compared to Placebo and Midazolam in Colonoscopy Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Colonoscopy"
      ],
      "interventions": [
        {
          "name": "Remimazolam",
          "type": "DRUG"
        },
        {
          "name": "Midazolam",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Paion UK Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 461,
      "start_date": "2015-03-30",
      "completion_date": "2016-04-19",
      "has_results": true,
      "last_update_posted_date": "2020-10-20",
      "last_synced_at": "2026-09-14T20:28:30.592Z",
      "location_count": 13,
      "location_summary": "Mobile, Alabama • Anaheim, California • Chula Vista, California + 10 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Chula Vista",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02290873"
    },
    {
      "nct_id": "NCT00413582",
      "title": "Pain Management for Pectus Excavatum Repair",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postoperative Pain"
      ],
      "interventions": [
        {
          "name": "Epidural Analgesia",
          "type": "DRUG"
        },
        {
          "name": "Patient-Controlled IV Analgesia",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Children's Mercy Hospital Kansas City",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "8 Years to 18 Years"
      },
      "enrollment_count": 110,
      "start_date": "2006-10",
      "completion_date": "2010-10",
      "has_results": true,
      "last_update_posted_date": "2012-01-16",
      "last_synced_at": "2026-09-14T20:28:30.592Z",
      "location_count": 1,
      "location_summary": "Kansas City, Missouri",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00413582"
    },
    {
      "nct_id": "NCT02808962",
      "title": "Optimal Performance of RFA of the Nerves Supplying the Posterior Sacroiliac Joint Complex.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis Nos, of Sacroiliac Joint"
      ],
      "interventions": [
        {
          "name": "Cooled RFA of sacral lateral branches",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2016-02-17",
      "completion_date": "2022-06-01",
      "has_results": false,
      "last_update_posted_date": "2022-07-11",
      "last_synced_at": "2026-09-14T20:28:30.592Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02808962"
    },
    {
      "nct_id": "NCT07443254",
      "title": "Prospective IR-led Sedation Feasibility",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Anesthesia",
        "Sedation and Analgesia",
        "Interventional Radiology"
      ],
      "interventions": [
        {
          "name": "ketamine",
          "type": "DRUG"
        },
        {
          "name": "Fentanyl (IV)",
          "type": "DRUG"
        },
        {
          "name": "Midazolam",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "CAMC Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2026-03-02",
      "completion_date": "2027-04-03",
      "has_results": false,
      "last_update_posted_date": "2026-03-09",
      "last_synced_at": "2026-09-14T20:28:30.592Z",
      "location_count": 1,
      "location_summary": "Charleston, West Virginia",
      "locations": [
        {
          "city": "Charleston",
          "state": "West Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07443254"
    },
    {
      "nct_id": "NCT00462644",
      "title": "Evaluation of Etomidate on Adrenal Function in Trauma Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Adrenal Insufficiency"
      ],
      "interventions": [
        {
          "name": "RSI sedation with etomidate/succinylcholine",
          "type": "DRUG"
        },
        {
          "name": "RSI sedation with fentanyl/midazolam/succinylcholine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Tennessee",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2006-02",
      "completion_date": "2006-09",
      "has_results": true,
      "last_update_posted_date": "2010-02-23",
      "last_synced_at": "2026-09-14T20:28:30.592Z",
      "location_count": 1,
      "location_summary": "Chattanooga, Tennessee",
      "locations": [
        {
          "city": "Chattanooga",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00462644"
    },
    {
      "nct_id": "NCT02937506",
      "title": "Patient Satisfaction With Propofol for Out Patient Colonoscopy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Colon Cancer",
        "IBS",
        "Polyps"
      ],
      "interventions": [
        {
          "name": "Propofol",
          "type": "DRUG"
        },
        {
          "name": "Fentanyl Plus Midazolam",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mount Carmel Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 600,
      "start_date": "2013-11",
      "completion_date": "2016-08",
      "has_results": true,
      "last_update_posted_date": "2017-12-26",
      "last_synced_at": "2026-09-14T20:28:30.592Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02937506"
    },
    {
      "nct_id": "NCT02410460",
      "title": "Anesthetics in Rhytidoplasty - A Comparison Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rhytidoplasty"
      ],
      "interventions": [
        {
          "name": "clonidine",
          "type": "DRUG"
        },
        {
          "name": "glycopyrrolate",
          "type": "DRUG"
        },
        {
          "name": "propofol",
          "type": "DRUG"
        },
        {
          "name": "ketamine",
          "type": "DRUG"
        },
        {
          "name": "marcaine",
          "type": "DRUG"
        },
        {
          "name": "scopolamine",
          "type": "DRUG"
        },
        {
          "name": "midazolam",
          "type": "DRUG"
        },
        {
          "name": "ondansetron",
          "type": "DEVICE"
        },
        {
          "name": "metoclopramide",
          "type": "DRUG"
        },
        {
          "name": "lidocaine",
          "type": "DRUG"
        },
        {
          "name": "famotidine",
          "type": "DRUG"
        },
        {
          "name": "desflurane",
          "type": "DRUG"
        },
        {
          "name": "sevoflurane",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Mercy Facial Plastic Surgery Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2013-09",
      "completion_date": "2014-06",
      "has_results": false,
      "last_update_posted_date": "2015-04-07",
      "last_synced_at": "2026-09-14T20:28:30.592Z",
      "location_count": 1,
      "location_summary": "Springfield, Missouri",
      "locations": [
        {
          "city": "Springfield",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02410460"
    }
  ]
}