{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Prosthetic+Knee",
    "query": {
      "intervention": "Prosthetic Knee"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 67,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Prosthetic+Knee&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-08T00:01:36.824Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07159490",
      "title": "Lower Limb Prostheses for Individuals Who Carry Infants, Toddlers, and Other Loads",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation",
        "Prosthesis User"
      ],
      "interventions": [
        {
          "name": "Standard-of-care prosthetic foot",
          "type": "DEVICE"
        },
        {
          "name": "Standard-of-care prosthetic foot with heel-stiffening wedge",
          "type": "DEVICE"
        },
        {
          "name": "Standard-of-care prosthetic foot of one category greater stiffness",
          "type": "DEVICE"
        },
        {
          "name": "Dual keel prosthetic foot",
          "type": "DEVICE"
        },
        {
          "name": "Powered ankle-foot",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "VA Puget Sound Health Care System",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 13,
      "start_date": "2020-12-03",
      "completion_date": "2025-10-01",
      "has_results": true,
      "last_update_posted_date": "2026-02-12",
      "last_synced_at": "2026-09-08T00:01:36.824Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07159490"
    },
    {
      "nct_id": "NCT04784429",
      "title": "Assessing Outcomes With Microprocessor Knee Utilization in a K2 Population",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lower Limb Amputation Above Knee (Injury)",
        "Congenital Amputation of Lower Limb",
        "Lower Limb Amputation Knee"
      ],
      "interventions": [
        {
          "name": "Kenevo or C-Leg 4",
          "type": "DEVICE"
        },
        {
          "name": "Non microprocessor controlled knee (NMPK)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Otto Bock Healthcare Products GmbH",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 107,
      "start_date": "2021-06-11",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-02-09",
      "last_synced_at": "2026-09-08T00:01:36.824Z",
      "location_count": 90,
      "location_summary": "Dothan, Alabama • Gilbert, Arizona • Phoenix, Arizona + 85 more",
      "locations": [
        {
          "city": "Dothan",
          "state": "Alabama"
        },
        {
          "city": "Gilbert",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Sun City West",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04784429"
    },
    {
      "nct_id": "NCT02240186",
      "title": "Comparative Effectiveness Between Microprocessor Knees and Non-Microprocessor Knees",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lower Limb Amputation Above Knee (Injury)"
      ],
      "interventions": [
        {
          "name": "Microprocessor Knee (MPK)",
          "type": "DEVICE"
        },
        {
          "name": "Non-Microprocessor Knee (NMPK)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2014-06",
      "completion_date": "2017-12",
      "has_results": true,
      "last_update_posted_date": "2018-12-12",
      "last_synced_at": "2026-09-08T00:01:36.824Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02240186"
    },
    {
      "nct_id": "NCT06733597",
      "title": "Femoral BMD Change Following Cemented or Cementless Total Knee Arthroplasty",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Arthropathy"
      ],
      "interventions": [
        {
          "name": "Cement",
          "type": "PROCEDURE"
        },
        {
          "name": "Cementless",
          "type": "OTHER"
        },
        {
          "name": "Manual Surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "Robotic Surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2025-03-06",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2026-02-19",
      "last_synced_at": "2026-09-08T00:01:36.824Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06733597"
    },
    {
      "nct_id": "NCT05267639",
      "title": "Clinical Outcomes With Passive MPKs vs. Powered Prosthetic Knees",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation",
        "Amputation; Traumatic, Leg, Lower",
        "Limb; Absence, Congenital, Lower",
        "Prosthesis User",
        "Lower Limb Amputation Above Knee (Injury)",
        "Amputation; Traumatic, Leg: Thigh, Between Hip and Knee"
      ],
      "interventions": [
        {
          "name": "Power Knee",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Liberating Technologies, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 13,
      "start_date": "2022-05-01",
      "completion_date": "2024-08-28",
      "has_results": true,
      "last_update_posted_date": "2025-06-26",
      "last_synced_at": "2026-09-08T00:01:36.824Z",
      "location_count": 2,
      "location_summary": "Holliston, Massachusetts • Austin, Texas",
      "locations": [
        {
          "city": "Holliston",
          "state": "Massachusetts"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05267639"
    },
    {
      "nct_id": "NCT04763759",
      "title": "Study to Evaluate Safety and Activity of TRL1068 in Prosthetic Joint Infections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Prosthetic Joint Infection"
      ],
      "interventions": [
        {
          "name": "TRL1068, a human monoclonal antibody",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Trellis Bioscience LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 15,
      "start_date": "2021-02-08",
      "completion_date": "2024-03-13",
      "has_results": false,
      "last_update_posted_date": "2024-11-21",
      "last_synced_at": "2026-09-08T00:01:36.824Z",
      "location_count": 9,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • Santa Monica, California + 6 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04763759"
    },
    {
      "nct_id": "NCT05884203",
      "title": "Improving Prosthetic Provision in Rural Communities: Limb Scanning With Caregiver Assistance",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lower Extremity Amputation"
      ],
      "interventions": [
        {
          "name": "Caregiver socket",
          "type": "DEVICE"
        },
        {
          "name": "Prosthetist socket",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 17,
      "start_date": "2023-07-01",
      "completion_date": "2027-04-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-22",
      "last_synced_at": "2026-09-08T00:01:36.824Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05884203"
    },
    {
      "nct_id": "NCT04038151",
      "title": "Intuitive Control of a Hybrid Prosthetic Leg During Ambulation",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Hybrid Leg",
          "type": "DEVICE"
        },
        {
          "name": "Prescribed Passive Prosthesis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Shirley Ryan AbilityLab",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "18 Years to 95 Years"
      },
      "enrollment_count": 20,
      "start_date": "2018-12-01",
      "completion_date": "2025-06-30",
      "has_results": false,
      "last_update_posted_date": "2024-05-17",
      "last_synced_at": "2026-09-08T00:01:36.824Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04038151"
    },
    {
      "nct_id": "NCT07613502",
      "title": "Bio Leg: Advancing Mobility (BAM)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation of Lower Limb Above Knee",
        "Amputee",
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Bio Leg",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 12,
      "start_date": "2026-06-01",
      "completion_date": "2028-07",
      "has_results": false,
      "last_update_posted_date": "2026-07-06",
      "last_synced_at": "2026-09-08T00:01:36.824Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07613502"
    },
    {
      "nct_id": "NCT06138977",
      "title": "Controlling Locomotion Over Continuously Varying Activities for Agile Powered Prosthetic Legs",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Powered prosthesis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2023-12-06",
      "completion_date": "2028-01-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-13",
      "last_synced_at": "2026-09-08T00:01:36.824Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06138977"
    }
  ]
}