{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Proton+beam+therapy&page=2", "query": { "intervention": "Proton beam therapy", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 854, "total_pages": 86, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Proton+beam+therapy&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Proton+beam+therapy&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-30T11:53:21.356Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03921008", "title": "Induction Paclitaxel Followed by Concurrent Paclitaxel and Radiation Therapy for Cutaneous Angiosarcoma", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Cutaneous Angiosarcoma" ], "interventions": [ { "name": "Paclitaxel", "type": "DRUG" }, { "name": "Radiation therapy", "type": "RADIATION" }, { "name": "Research blood draw", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "RADIATION", "PROCEDURE" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2019-05-21", "completion_date": "2028-01-16", "has_results": false, "last_update_posted_date": "2026-01-21", "last_synced_at": "2026-09-30T11:53:21.356Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT03921008" }, { "nct_id": "NCT05665725", "title": "Siltuximab for the Prevention of CAR T Cell Related Cytokine Release Syndrome in Patients With CD19 Positive Non-Hodgkin Lymphoma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Non-Hodgkin Lymphoma" ], "interventions": [ { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "Computed Tomography", "type": "PROCEDURE" }, { "name": "Positron Emission Tomography", "type": "PROCEDURE" }, { "name": "Siltuximab", "type": "BIOLOGICAL" } ], "intervention_types": [ "PROCEDURE", "BIOLOGICAL" ], "sponsor": "Timothy Voorhees", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 11, "start_date": "2023-01-31", "completion_date": "2024-09-06", "has_results": false, "last_update_posted_date": "2025-01-31", "last_synced_at": "2026-09-30T11:53:21.356Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT05665725" }, { "nct_id": "NCT03094416", "title": "Levothyroxine Sodium in Thyroidectomized Patients Taking Proton Pump Inhibitors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Hypothyroidism;Postablative" ], "interventions": [ { "name": "levothyroxine sodium capsule", "type": "DRUG" }, { "name": "Proton pump inhibitor (PPI)", "type": "DRUG" }, { "name": "Levothyroxine Sodium (LT4) Tablets", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "IBSA Institut Biochimique SA", "sponsor_class": "INDUSTRY", 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"INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Adult Giant Cell Glioblastoma", "Adult Glioblastoma", "Adult Gliosarcoma" ], "interventions": [ { "name": "Cediranib Maleate", "type": "DRUG" }, { "name": "Diffusion Tensor Imaging", "type": "PROCEDURE" }, { "name": "Diffusion Weighted Imaging", "type": "PROCEDURE" }, { "name": "Dynamic Contrast-Enhanced Magnetic Resonance Imaging", "type": "PROCEDURE" }, { "name": "Fludeoxyglucose F-18", "type": "RADIATION" }, { "name": "Intensity-Modulated Radiation Therapy", "type": "RADIATION" }, { "name": "Laboratory Biomarker Analysis", "type": "OTHER" }, { "name": "Perfusion Magnetic Resonance Imaging", "type": "PROCEDURE" }, { "name": "Positron Emission Tomography", "type": "PROCEDURE" }, { "name": "Temozolomide", "type": "DRUG" } ], "intervention_types": [ "DRUG", "PROCEDURE", "RADIATION", "OTHER" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 46, "start_date": "2008-04", "completion_date": "2014-04", "has_results": false, "last_update_posted_date": "2023-06-06", "last_synced_at": "2026-09-30T11:53:21.356Z", "location_count": 2, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00662506" }, { "nct_id": "NCT01449149", "title": "Proton Radiation for Chordomas and Chondrosarcomas", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Chordomas", "Chondrosarcomas" ], "interventions": [ { "name": "Proton Therapy", "type": "RADIATION" } ], "intervention_types": [ "RADIATION" ], "sponsor": "Abramson Cancer Center at Penn Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 54, "start_date": "2010-03", "completion_date": "2025-09-04", "has_results": true, "last_update_posted_date": "2025-12-05", "last_synced_at": "2026-09-30T11:53:21.356Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01449149" }, { "nct_id": "NCT03168737", "title": "18F-Fluoroazomycin Arabinoside PET-CT in Diagnosing Solid Tumors in Patients", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Malignant Breast Neoplasm", "Malignant Colorectal Neoplasm", "Malignant Pancreatic Neoplasm", "Malignant Solid Neoplasm" ], "interventions": [ { "name": "Computed Tomography", "type": "PROCEDURE" }, { "name": "Fluorine F 18-fluoroazomycin Arabinoside", "type": "RADIATION" }, { "name": "Positron Emission Tomography", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE", "RADIATION" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 25, "start_date": "2017-09-22", "completion_date": "2027-04-30", "has_results": false, "last_update_posted_date": "2026-07-30", "last_synced_at": "2026-09-30T11:53:21.356Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03168737" }, { "nct_id": "NCT01180881", "title": "Neurobehavioral Functioning in Pediatric Brain Tumor Patients After Proton Beam Radiation Treatment", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Brain Tumor", "Central Nervous System Neoplasms" ], "interventions": [], "intervention_types": [], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "25 Years", "sex": "ALL", "summary": "1 Year to 25 Years" }, "enrollment_count": 155, "start_date": "2009-10", "completion_date": "2018-01-01", "has_results": false, "last_update_posted_date": "2025-11-10", "last_synced_at": "2026-09-30T11:53:21.356Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01180881" }, { "nct_id": "NCT03539198", "title": "Study of Proton SBRT and Immunotherapy for Recurrent/Progressive Locoregional or Metastatic Head and Neck Cancer", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Head and Neck Cancer" ], "interventions": [ { "name": "Proton Stereotactic Body Radiation Therapy (SBRT) (5 fractions; 3500-4500 cGy)", "type": "RADIATION" }, { "name": "Proton Stereotactic Body Radiation Therapy (SBRT) (3-5 fractions; various dose and fractionation regimens depending on treatment site).", "type": "RADIATION" }, { "name": "Nivolumab 3 mg/kg IV q2 weeks", "type": "DRUG" }, { "name": "Proton or Photon SBRT (3-5 fractions; various dose and fractionation regimens depending on treatment site).", "type": "RADIATION" } ], "intervention_types": [ "RADIATION", "DRUG" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 19, "start_date": "2018-07-03", "completion_date": "2020-01-06", "has_results": false, "last_update_posted_date": "2024-11-14", "last_synced_at": "2026-09-30T11:53:21.356Z", "location_count": 2, "location_summary": "Scottsdale, Arizona • Rochester, Minnesota", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT03539198" }, { "nct_id": "NCT02039778", "title": "Stem Cell Radiotherapy and Temozolomide for Newly Diagnosed High-grade Glioma", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Glioblastoma", "Malignant Glioma", "Brain Tumors", "Anaplastic Astrocytoma" ], "interventions": [ { "name": "Stem Cell Radiotherapy (ScRT) and Temozolomide", "type": "RADIATION" } ], "intervention_types": [ "RADIATION" ], "sponsor": "Beth Israel Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 4, "start_date": "2013-12", "completion_date": "2015-12", "has_results": true, "last_update_posted_date": "2017-06-05", "last_synced_at": "2026-09-30T11:53:21.356Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02039778" }, { "nct_id": "NCT06793943", "title": "A Study of Interaction of Zasocitinib (TAK-279) With Other Medicines in Healthy Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy Volunteers" ], "interventions": [ { "name": "Zasocitinib", "type": "DRUG" }, { "name": "COC", "type": "DRUG" }, { "name": "Metformin", "type": "DRUG" }, { "name": "Digoxin", "type": "DRUG" }, { "name": "Esomeprazole", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 78, "start_date": "2025-01-23", "completion_date": "2025-03-30", "has_results": false, "last_update_posted_date": "2025-04-04", "last_synced_at": "2026-09-30T11:53:21.356Z", "location_count": 1, "location_summary": "Tempe, Arizona", "locations": [ { "city": "Tempe", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT06793943" } ] }